Acp6 - acid phosphatase 6, lysophosphatidic (house mouse)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2024-12-23
Description
Predicted to enable lysophosphatidic acid phosphatase activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in mitochondrion. Is expressed in 2-cell stage embryo and 4-cell stage embryo. Orthologous to human ACP6 (acid phosphatase 6, lysophosphatidic).
- 5730559A09Rik
- ACPL1
- mPACPL1
- lysophosphatidic acid phosphatase type 6
- PACPL1
- acid phosphatase like 1
- acid phosphatase-like protein 1
Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid.
Isoform
UniProt ID
RefSeq Accession
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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