cobS - cobalamin 5'-phosphate synthase (Escherichia coli str. K-12 substr. MG1655)
Gene
Symbol
Dates
- Create:2016-09-14
- Modify:2025-01-13
Description
Escherichia coli K-12, as well as natural isolates, can synthesize cobalamin only when supplied with the intermediate cobinamide . cobS encodes a predicted cobalamin synthase . [More information is available at EcoCyc: EG12150].
ECK1987
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate (By similarity).
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- PubChem
- NCBI Gene Expression Omnibus (GEO)
- STRING: functional protein association networks
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- Wikidatacobalamin 5'-phosphate synthase b1992https://www.wikidata.org/wiki/Q23089068
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