ilvC - acetohydroxy-acid isomeroreductase (NADP-dependent) (Bacillus subtilis subsp. subtilis str. 168)
Gene
Symbol
Dates
- Create:2016-09-14
- Modify:2025-01-20
Description
Please note that currently there is no data available in PubChem associated with ilvC - acetohydroxy-acid isomeroreductase (NADP-dependent) (Bacillus subtilis subsp. subtilis str. 168). However, annotations from external sources are available.
BSU28290
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
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- PubChem
- NCBI Gene Expression Omnibus (GEO)
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- Wikidataketol-acid reductoisomerase BSU28290https://www.wikidata.org/wiki/Q23350180
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