GPRC5C - G protein-coupled receptor class C group 5 member C (human)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-02-02
Description
The protein encoded by the GPRC5C gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Predicted to enable protein kinase activator activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in extracellular exosome. Part of receptor complex.
- RAIG-3
- RAIG3
- G-protein coupled receptor family C group 5 member C
- orphan G-protein coupled receptor
- retinoic acid responsive gene protein
- retinoic acid-induced gene 3 protein
This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
Isoform
UniProt ID
RefSeq Accession
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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