sls - sallimus (fruit fly)
Gene
Symbol
Dates
- Create:2016-09-14
- Modify:2025-01-18
Description
Enables actin binding activity. A structural constituent of muscle. Involved in several processes, including chromosome organization; muscle attachment; and striated muscle cell differentiation. Located in Z disc; condensed nuclear chromosome; and striated muscle myosin thick filament. Is expressed in several structures, including adult head; embryonic myoblast; embryonic/larval midgut primordium; ganglia; and muscle cell. Used to study myopathy.
- 0020/01
- CG18242
- CG18245
- CG18857
- CG1915
- CT41299
- D-Titin
- D-titin
- Dmel\CG1915
- KZ
- Ket
- Kettin
- MCP
- SLS
- Sls
- TITIN
- Titin
- anon-CREST
- d-titin
- ket
- kettin
- l(3)62Ca
- l(3)Ca
- l(3)S002001
- l(3)dre8
- l(3)j1D7
- l(3)rL182
- sal
- sam
- sls/kettin
- titin
- CG1915-PA
- CG1915-PD
- CG1915-PP
- CG1915-PQ
- CG1915-PR
- CG1915-PS
- CG1915-PT
- CG1915-PU
- CG1915-PV
- CG1915-PW
- CG1915-PX
- CG1915-PY
- CG1915-PZ
- D-Titin/Kettin
- D-titan
- D-titin
- D-titin-KZ
- dtitin
- kettin
- lethal (3) S002001
- lethal(3)62Ca
- mitotic chromosomal protein
- salimus
- sls-PA
- sls-PD
- sls-PP
- sls-PQ
- sls-PR
- sls-PS
- sls-PT
- sls-PU
- sls-PV
- sls-PW
- sls-PX
- sls-PY
- sls-PZ
- titin
- M-Protein (muscle)
- M-Line 185 kDa Protein
- M-Band Proteins
- Muscle M-Line Protein
- Myomesin
- Skelemins
- Titin
- Titin 1
- Titin Kinase
- Titin 2
- alpha-Connectin
- beta-Connectin
Key component in the assembly and functioning of adult and embryonic striated muscles and muscle tendons. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.
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