Pli - Pellino (fruit fly)
Gene
Symbol
Dates
- Create:2016-09-14
- Modify:2025-01-27
Description
Enables kinase regulator activity and ubiquitin-protein transferase activity. Involved in several processes, including protein K48-linked ubiquitination; regulation of Toll signaling pathway; and regulation of defense response. Located in cytoplasmic side of plasma membrane and cytosol. Is expressed in adult fat body and organism. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to several human genes including PELI2 (pellino E3 ubiquitin protein ligase family member 2).
- CG5212
- Dmel\CG5212
- PAP
- PELLINO
- pellino
- pli
- pellino
- CG5212-PA
- CG5212-PB
- Pli-PA
- Pli-PB
- pelle associated protein
Scaffold protein involved in the Toll signaling pathway via its interaction with pelle/pll kinase.
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
- NCBI GeneLICENSENCBI Website and Data Usage Policies and Disclaimershttps://www.ncbi.nlm.nih.gov/home/about/policies/
- PubChem
- Alliance of Genome ResourcesLICENSEAll annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).https://www.alliancegenome.org/privacy-warranty-licensing
- BioGRIDLICENSEThe MIT License (MIT); Copyright Mike Tyers Labhttps://wiki.thebiogrid.org/doku.php/terms_and_conditions
- Database of Interacting Proteins (DIP)LICENSEAll DIP database records available under the terms set by the Creative Commons Attribution-NoDerivs License.https://dip.doe-mbi.ucla.edu/dip/termsofuse.html
- STRING: functional protein association networks
- Comparative Toxicogenomics Database (CTD)LICENSEIt is to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of NC State University.http://ctdbase.org/about/legal.jsp
- FlyBaseLICENSEAll annotations and data produced by FlyBase that are accessible from flybase.org are distributed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).https://wiki.flybase.org/wiki/FlyBase:About#FlyBase_Licenses_and_Availability
- NCBI Gene Expression Omnibus (GEO)
- Swiss Institute of Bioinformatics Bgee
- UniProtLICENSEWe have chosen to apply the Creative Commons Attribution (CC BY 4.0, http://creativecommons.org/licenses/by/4.0/) License to all copyrightable parts of our databases.https://www.uniprot.org/help/license
- VEuPathDB: The Eukaryotic Pathogen, Vector and Host Informatics ResourceLICENSEAll data on VEuPathDB websites are provided freely for public use.https://veupathdb.org/veupathdb/app/static-content/about.html
- Wikidata
- Gene Ontology (GO)LICENSEGene Ontology Consortium data and data products are licensed under the Creative Commons Attribution 4.0 Unported License (https://creativecommons.org/licenses/by/4.0/legalcode)http://geneontology.org/docs/go-citation-policy/Biological Processhttp://www.geneontology.org/
- AlphaFold DBLICENSEAll of the data provided is freely available for both academic and commercial use under Creative Commons Attribution 4.0 (CC-BY 4.0) licence terms.https://alphafold.ebi.ac.uk/faq
CONTENTS