Sdhd - succinate dehydrogenase complex subunit D (Norway rat)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-18
Description
Predicted to enable heme binding activity; succinate dehydrogenase (quinone) activity; and ubiquinone binding activity. Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone and tricarboxylic acid cycle. Predicted to act upstream of or within cellular response to hypoxia and regulation of catecholamine secretion. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex II (succinate dehydrogenase). Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; mitochondrial complex II deficiency; and paraganglioma. Orthologous to human SDHD (succinate dehydrogenase complex subunit D).
- CII-4
- QPs3
- cybS
- succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
- malate dehydrogenase [quinone] cytochrome b small subunit
- succinate dehydrogenase complex, subunit D, integral membrane protein
- succinate-ubiquinone oxidoreductase cytochrome b small subunit
- succinate-ubiquinone reductase membrane anchor subunit
- SDHD (human)
- SDHD (black-footed ferret)
- SDHD (European mink)
- SDHD (Ahaetulla prasina)
- SDHD (red-backed fairy wren)
- SDHD (Oenanthe melanoleuca)
- SDHD (Chinese forest musk deer)
- SDHD (raccoon dog)
- SDHD (Leopard gecko)
- SDHD (Pteronotus mesoamericanus)
- SDHD (lesser prairie-chicken)
- SDHD (takin)
- SDHD (yellow-footed antechinus)
- SDHD (California condor)
- SDHD (Macaca thibetana thibetana)
- SDHD (Northern goshawk)
- SDHD (snow leopard)
- SDHD (rock ptarmigan)
- SDHD (Eurasian river otter)
- SDHD (bobcat)
- SDHD (greater spear-nosed bat)
- SDHD (Ring-tailed lemur)
- SDHD (Agile Gracile Mouse Opossum)
- SDHD (Komodo dragon)
- SDHD (Asiatic toad)
- SDHD (American mink)
- SDHD (leopard cat)
- SDHD (wapiti)
- SDHD (Arctic fox)
- SDHD (rufous-necked snowfinch)
- SDHD (white-rumped snowfinch)
- SDHD (jaguarundi)
- SDHD (common toad)
- SDHD (common frog)
- SDHD (scimitar-horned oryx)
- SDHD (Barn swallow)
- SDHD (large flying fox)
- SDHD (Tiger rattlesnake)
- SDHD (striped hyena)
- SDHD (Iberian mole)
- SDHD (Jamaican fruit-eating bat)
- SDHD (Sturnira hondurensis)
- SDHD (Kuhl's pipistrelle)
- SDHD (Myotis myotis)
- SDHD (Pallas's mastiff bat)
- SDHD (Southern elephant seal)
- SDHD (giant panda)
- SDHD (Pantherophis guttatus)
- SDHD (Gaboon caecilian)
- SDHD (Francois's langur)
- SDHD (greater horseshoe bat)
- SDHD (sea lamprey)
- SDHD (Abingdon island giant tortoise)
- SDHD (vaquita)
- SDHD (silvery gibbon)
- SDHD (ring-necked pheasant)
- SDHD (Kakapo)
- SDHD (Microcaecilia unicolor)
- SDHD (Aquila chrysaetos chrysaetos)
- SDHD (platypus)
- SDHD (pale spear-nosed bat)
- SDHD (Steller sea lion)
- SDHD (willow flycatcher)
- SDHD (California sea lion)
- SDHD (burrowing owl)
- SDHD (eastern brown snake)
- SDHD (Okarito brown kiwi)
- SDHD (Nothoprocta perdicaria)
- SDHD (red fox)
- SDHD (puma)
- SDHD (dingo)
- SDHD (gelada)
- SDHD (Yangtze finless porpoise)
- SDHD (common vampire bat)
- SDHD (blue tit)
- SDHD (Ugandan red Colobus)
- SDHD (beluga whale)
- SDHD (Hawaiian monk seal)
- SDHD (white-rumped munia)
- SDHD (helmeted guineafowl)
- SDHD (koala)
- SDHD (central bearded dragon)
- SDHD (great roundleaf bat)
- SDHD (Australian saltwater crocodile)
- SDHD (Gharial)
- SDHD (leopard)
- SDHD (western lowland gorilla)
- SDHD (Nanorana parkeri)
- SDHD (black snub-nosed monkey)
- SDHD (Malayan pangolin)
- SDHD (Panamanian white-faced capuchin)
- SDHD (rabbit)
- SDHD (Collared flycatcher)
- SDHD (Miniopterus natalensis)
- SDHD (Egyptian rousette)
- SDHD (Japanese quail)
- SDHD (Taiwan habu)
- SDHD (Great Tit)
- SDHD (Gekko japonicus)
- SDHD (Rhesus monkey)
- SDHD (cheetah)
- SDHD (Common starling)
- SDHD (ass)
- SDHD (Swan goose)
- SDHD (gray mouse lemur)
- SDHD (Coquerel's sifaka)
- SDHD (sooty mangabey)
- SDHD (drill)
- SDHD (Colobus angolensis palliatus)
- SDHD (pig-tailed macaque)
- SDHD (large flying fox)
- SDHD (Arabian camel)
- SDHD (Bactrian camel)
- SDHD (Bison bison bison)
- SDHD (turkey)
- SDHD (bald eagle)
- SDHD (Corvus cornix cornix)
- SDHD (golden snub-nosed monkey)
- SDHD (East African grey crowned-crane)
- SDHD (White-tailed tropicbird)
- SDHD (white-throated tinamou)
- SDHD (speckled mousebird)
- SDHD (brown roatelo)
- SDHD (chuck-will's-widow)
- SDHD (sunbittern)
- SDHD (Buceros rhinoceros silvestris)
- SDHD (Macqueen's bustard)
- SDHD (yellow-throated sandgrouse)
- SDHD (Kea)
- SDHD (chimney swift)
- SDHD (red-crested turaco)
- SDHD (common barn owl)
- SDHD (cuckoo roller)
- SDHD (hoatzin)
- SDHD (white-tailed eagle)
- SDHD (Downy woodpecker)
- SDHD (killdeer)
- SDHD (bar-tailed trogon)
- SDHD (red-throated loon)
- SDHD (Red-legged seriema)
- SDHD (African ostrich)
- SDHD (little egret)
- SDHD (Northern fulmar)
- SDHD (common cuckoo)
- SDHD (Dalmatian pelican)
- SDHD (crested ibis)
- SDHD (Adelie penguin)
- SDHD (emperor penguin)
- SDHD (Common canary)
- SDHD (rifleman)
- SDHD (carmine bee-eater)
- SDHD (polar bear)
- SDHD (American crow)
- SDHD (Sunda flying lemur)
- SDHD (Przewalski's horse)
- SDHD (big brown bat)
- SDHD (Philippine tarsier)
- SDHD (green monkey)
- SDHD (Yangtze River dolphin)
- SDHD (Burmese python)
- SDHD (minke whale)
- SDHD (sperm whale)
- SDHD (tiger)
- SDHD (black flying fox)
- SDHD (Myotis davidii)
- SDHD (Weddell seal)
- SDHD (American alligator)
- SDHD (alpaca)
- SDHD (Wild Bactrian camel)
- SDHD (Chinese soft-shelled turtle)
- SDHD (little brown bat)
- SDHD (water buffalo)
- SDHD (Chinese alligator)
- SDHDB (coelacanth)
- SDHD (wild yak)
- SDHD (Brandt's bat)
- SDHD (crab-eating macaque)
- SDHD (Tibetan ground-tit)
- SDHD (rock pigeon)
- SDHD (white-throated sparrow)
- SDHD (Saker falcon)
- SDHD (medium ground-finch)
- Sdhd (long-tailed chinchilla)
- SDHD (peregrine falcon)
- SDHD (mallard)
- SDHD (domestic ferret)
- SDHD (small Madagascar hedgehog)
- SDHD (European shrew)
- SDHD (American pika)
- SDHD (nine-banded armadillo)
- SDHD (Pacific walrus)
- SDHD (killer whale)
- SDHD (sheep)
- SDHD (domestic cat)
- SDHD (Bolivian squirrel monkey)
- SDHD (olive baboon)
- SDHD (small-eared galago)
- SDHD (Tasmanian devil)
- SDHD (goat)
- SDHD (African savanna elephant)
- SDHD (horse)
- SDHD (northern white-cheeked gibbon)
- SDHD (white-tufted-ear marmoset)
- SDHD (zebra finch)
- SDHD (Sumatran orangutan)
- SDHD (pig)
- SDHD (gray short-tailed opossum)
- SDHD (dog)
- SDHD (chimpanzee)
- sdhdb (zebrafish)
- SDHD (chicken)
- sdhd (tropical clawed frog)
- SDHD (domestic cattle)
- Sdhd (house mouse)
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity).
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- PubChem
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- STRING: functional protein association networks
- Swiss Institute of Bioinformatics Bgee
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