Semp1 - Seminal metalloprotease-1 (fruit fly)
Gene
Symbol
Dates
- Create:2016-09-14
- Modify:2025-01-17
Description
Enables endopeptidase activity. Involved in cell migration and protein processing. Located in extracellular space. Is expressed in egg; female reproductive system; oviduct; and uterus. Used to study prostate cancer. Orthologous to human MEP1A (meprin A subunit alpha) and MEP1B (meprin A subunit beta).
- AST
- BACR44L22.8
- BG:BACR44L22.8
- CG11864
- Dmel\CG11864
- semp1
- seminal metalloprotease-1
- CG11864-PA
- Semp1-PA
Seminal fluid metalloprotease which is transferred to females during mating and is required for processing of two other seminal fluid proteins Acp26Aa and Acp36DE in mated females.
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- STRING: functional protein association networks
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