CG6724 - uncharacterized protein (fruit fly)
Gene
Symbol
Dates
- Create:2016-09-14
- Modify:2025-01-17
Description
Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in cytosol and plasma membrane. Is expressed in several structures, including adult brain cell body rind; adult gnathal ganglion; adult neuromere; larval muscle cell; and mesoderm. Orthologous to human WDR12 (WD repeat domain 12).
- Dmel\CG6724
- CG6724-PA
- CG6724-PB
- ribosome biogenesis protein WDR12 homolog
- LOC6731883 (Drosophila simulans)
- LOC6641752 (Drosophila willistoni)
- LOC6629233 (Drosophila virilis)
- LOC6612061 (Drosophila sechellia)
- LOC6596580 (Drosophila persimilis)
- LOC6577286 (Drosophila mojavensis)
- LOC6566798 (Drosophila grimshawi)
- LOC6542886 (Drosophila erecta)
- LOC6527185 (Drosophila yakuba)
- LOC6496895 (Drosophila ananassae)
- LOC6033337 (southern house mosquito)
- LOC5565845 (yellow fever mosquito)
- LOC4816649 (Drosophila pseudoobscura)
- LOC1269902 (African malaria mosquito)
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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