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x16 - x16 splicing factor (fruit fly)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-18
Description
Enables mRNA binding activity. Involved in RNA splicing and regulation of RNA metabolic process. Located in nucleus. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in several structures, including CNS glial cell; embryonic/larval midgut primordium; ganglia; head epidermis primordium; and imaginal disc. Orthologous to several human genes including SRSF7 (serine and arginine rich splicing factor 7).

1 Names and Identifiers

1.1 Synonyms

  • 2/30
  • 9G8
  • CG10203
  • Dmel\CG10203
  • Dx16
  • Dxl6
  • RBP1-like
  • TN166
  • X16
  • X16/9G8
  • XL6
  • Xl6
  • anon-WO0118547.78
  • d9G8
  • dx16
  • dxl6
  • l(2)k00230
  • xl6
  • CG10203-PA
  • CG10203-PB
  • x16-PA
  • x16-PB
  • xl6

1.2 Other Identifiers

1.2.1 Ensembl ID

1.2.2 Alliance Gene ID

1.2.3 Bgee Gene ID

1.2.4 FlyBase ID

1.2.5 VEuPathDB ID

1.2.6 Wikidata

3 Proteins

3.1 Protein Function

Serine/arginine-rich splicing factor (SR protein) involved in differential exon usage during RNA transcript processing, probably by binding exonic splicing enhancer elements and recruiting components of the splicing machinery (PMID: 17345156, PMID: 35780586). Binds RNA stem-loop structures with consensus sequence 5'-CCGUNUNKNW-3' (PMID: 17345156). Regulator of genes involved in lipid and carbohydrate metabolism, the immune response and the response to xenobiotics (PMID: 35780586).

3.2 Protein Isoforms

Isoform
Isoform A
UniProt ID
RefSeq Accession
Isoform
Isoform B
UniProt ID
RefSeq Accession

3.3 Protein Targets

4 BioAssays

4.1 RNAi BioAssays

5 Interactions and Pathways

5.1 Pathways

6 Biochemical Reactions

7 Expression

8 Literature

8.1 Consolidated References

8.2 Gene-Chemical Co-Occurrences in Literature

8.3 Gene-Gene Co-Occurrences in Literature

8.4 Gene-Disease Co-Occurrences in Literature

9 Classification

9.1 Gene Ontology: Biological Process

9.2 Gene Ontology: Cellular Component

9.3 Gene Ontology: Molecular Function

10 Information Sources

  1. NCBI Gene
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Alliance of Genome Resources
    LICENSE
    All annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
    https://www.alliancegenome.org/privacy-warranty-licensing
  4. FlyBase
    LICENSE
    All annotations and data produced by FlyBase that are accessible from flybase.org are distributed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
    https://wiki.flybase.org/wiki/FlyBase:About#FlyBase_Licenses_and_Availability
  5. NCBI Gene Expression Omnibus (GEO)
  6. Swiss Institute of Bioinformatics Bgee
    LICENSE
    Creative Commons Zero license (CC0)
    https://www.bgee.org/about/
  7. UniProt
    LICENSE
    We have chosen to apply the Creative Commons Attribution (CC BY 4.0, http://creativecommons.org/licenses/by/4.0/) License to all copyrightable parts of our databases.
    https://www.uniprot.org/help/license
  8. VEuPathDB: The Eukaryotic Pathogen, Vector and Host Informatics Resource
    LICENSE
    All data on VEuPathDB websites are provided freely for public use.
    https://veupathdb.org/veupathdb/app/static-content/about.html
  9. Wikidata
  10. Gene Ontology (GO)
    LICENSE
    Gene Ontology Consortium data and data products are licensed under the Creative Commons Attribution 4.0 Unported License (https://creativecommons.org/licenses/by/4.0/legalcode)
    http://geneontology.org/docs/go-citation-policy/
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