Dicer1 - dicer 1 ribonuclease III (Norway rat)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-18
Description
Predicted to enable several functions, including double-stranded RNA binding activity; endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters; and regulatory RNA binding activity. Predicted to contribute to pre-miRNA binding activity. Involved in several processes, including positive regulation of cell population proliferation; positive regulation of collagen biosynthetic process; and positive regulation of endothelial cell-matrix adhesion via fibronectin. Located in dendrite; endoplasmic reticulum-Golgi intermediate compartment; and growth cone. Biomarker of middle cerebral artery infarction. Human ortholog(s) of this gene implicated in DICER1 syndrome; gastrointestinal system cancer (multiple); multinodular goiter; nephroma; and pleuropulmonary blastoma. Orthologous to human DICER1 (dicer 1, ribonuclease III).
- endoribonuclease Dicer
- Dicer1, Dcr-1 homolog
- dicer 1, ribonuclease type III
- NCBI GeneLICENSENCBI Website and Data Usage Policies and Disclaimershttps://www.ncbi.nlm.nih.gov/home/about/policies/
- PubChem
- Alliance of Genome ResourcesLICENSEAll annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).https://www.alliancegenome.org/privacy-warranty-licensing
- NCBI Gene Expression Omnibus (GEO)
- Rat Genome Database (RGD)LICENSECreative Commons Attribution 4.0 International license (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
- Wikidata
CONTENTS