Slc44a4 - solute carrier family 44, member 4 (Norway rat)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-02-02
Description
Please note that currently there is no data available in PubChem associated with Slc44a4 - solute carrier family 44, member 4 (Norway rat). However, annotations from external sources are available.
Predicted to enable choline transmembrane transporter activity and thiamine pyrophosphate transmembrane transporter activity. Predicted to be involved in several processes, including acetylcholine biosynthetic process; choline transport; and otolith formation. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 72. Orthologous to human SLC44A4 (solute carrier family 44 member 4).
- Ng22
- choline transporter-like protein 4
- thiamine pyrophosphate transporter 1
Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (By similarity).
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- STRING: functional protein association networks
- Swiss Institute of Bioinformatics Bgee
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