Glyat - glycine-N-acyltransferase (Norway rat)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2024-12-15
Description
Predicted to enable glycine N-acyltransferase activity and glycine N-benzoyltransferase activity. Predicted to be involved in benzoyl-CoA metabolic process; glycine metabolic process; and monocarboxylic acid metabolic process. Predicted to be active in mitochondrion. Orthologous to human GLYAT (glycine-N-acyltransferase).
- glycine N-acyltransferase
- AAc
- acyl-CoA:glycine N-acyltransferase
- aralkyl acyl-CoA N-acyltransferase
- aralkyl acyl-CoA:amino acid N-acyltransferase
- benzoyl-coenzyme A:glycine N-acyltransferase
- glycine N-benzoyltransferase
- liver regeneration-related protein LRRG067
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate a multitude of substrates to form a variety of N-acylglycines, thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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