Irf8 - interferon regulatory factor 8 (Norway rat)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-18
Description
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to type II interferon and positive regulation of apoptotic process. Predicted to be located in cytoplasm and nucleoplasm. Human ortholog(s) of this gene implicated in Behcet's disease; immunodeficiency 32A; immunodeficiency 32B; multiple myeloma; and systemic lupus erythematosus. Orthologous to human IRF8 (interferon regulatory factor 8).
- ICSBP
- Icsbp1
- interferon consensus sequence binding protein 1
- transcription factor ICSBP
- NCBI GeneLICENSENCBI Website and Data Usage Policies and Disclaimershttps://www.ncbi.nlm.nih.gov/home/about/policies/
- PubChem
- Alliance of Genome ResourcesLICENSEAll annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).https://www.alliancegenome.org/privacy-warranty-licensing
- NCBI Gene Expression Omnibus (GEO)
- Rat Genome Database (RGD)LICENSECreative Commons Attribution 4.0 International license (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
- Wikidata
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