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Pde4c - phosphodiesterase 4C (Norway rat)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-28
Description
Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity and 3',5'-cyclic-GMP phosphodiesterase activity. Involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in cilium. Orthologous to human PDE4C (phosphodiesterase 4C).

1 Names and Identifiers

1.1 Synonyms

  • Dpde1
  • 3',5'-cyclic-AMP phosphodiesterase 4C
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4C
  • cAMP-specific 35-cyclic phosphodiesterase 4C
  • cAMP-specific phosphodiesterase 4C
  • phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)

1.1.1 MeSH Entry Terms

  • Cyclic Nucleotide Phosphodiesterase PDE4 Family
  • Cyclic Nucleotide Phosphodiesterases, Type 4A
  • Cyclic Nucleotide Phosphodiesterases, Type 4A5
  • Cyclic Nucleotide Phosphodiesterases, Type 4B
  • Cyclic Nucleotide Phosphodiesterases, Type 4C
  • Cyclic Nucleotide Phosphodiesterases, Type 4D
  • Cyclic Nucleotide Phosphodiesterases, Type 4D3
  • PDE4 Phosphodiesterases
  • PDE4D3 Phosphodiesterase
  • Phosphodiesterase 4
  • Phosphodiesterase 4A
  • Phosphodiesterase 4B
  • Phosphodiesterase 4C
  • Phosphodiesterase 4D
  • Phosphodiesterase IV
  • Phosphodiesterase-4
  • Type 4 Cyclic Nucleotide Phosphodiesterase
  • cAMP-Specific Phosphodiesterase 4A5

1.2 Other Identifiers

1.2.1 Ensembl ID

1.2.2 Alliance Gene ID

1.2.3 RGD ID

1.2.4 Wikidata

3 Chemicals and Bioactivities

3.1 Tested Compounds

4 BioAssays

4.1 Small-Molecule BioAssays

5 Interactions and Pathways

5.1 Pathways

6 Expression

7 Literature

7.1 Consolidated References

7.2 NLM Curated PubMed Citations

7.3 Gene-Chemical Co-Occurrences in Literature

7.4 Gene-Gene Co-Occurrences in Literature

7.5 Gene-Disease Co-Occurrences in Literature

8 Patents

8.1 Gene-Chemical Co-Occurrences in Patents

8.2 Gene-Gene Co-Occurrences in Patents

8.3 Gene-Disease Co-Occurrences in Patents

9 Classification

9.1 MeSH Tree

9.2 Gene Ontology: Biological Process

9.3 Gene Ontology: Cellular Component

9.4 Gene Ontology: Molecular Function

9.5 ChEMBL Target Tree

9.6 Enzyme Classification

10 Information Sources

  1. NCBI Gene
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. Medical Subject Headings (MeSH)
    LICENSE
    Works produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.
    https://www.nlm.nih.gov/copyright.html
    Cyclic Nucleotide Phosphodiesterases, Type 4
    https://meshb.nlm.nih.gov/record/ui?ui=D054703
  4. Alliance of Genome Resources
    LICENSE
    All annotations and data produced by Alliance members that are accessible from alliancegenome.org are distributed under a CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
    https://www.alliancegenome.org/privacy-warranty-licensing
  5. NCBI Gene Expression Omnibus (GEO)
  6. Rat Genome Database (RGD)
    LICENSE
    Creative Commons Attribution 4.0 International license (CC BY 4.0)
    https://creativecommons.org/licenses/by/4.0/
  7. Wikidata
  8. ChEMBL
    LICENSE
    Access to the web interface of ChEMBL is made under the EBI's Terms of Use (http://www.ebi.ac.uk/Information/termsofuse.html). The ChEMBL data is made available on a Creative Commons Attribution-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-sa/3.0/).
    http://www.ebi.ac.uk/Information/termsofuse.html
  9. Swiss Institute of Bioinformatics ENZYME
    LICENSE
    Copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/).
    https://enzyme.expasy.org/enzyme.get
    Enzyme Classification
    https://enzyme.expasy.org/
  10. Gene Ontology (GO)
    LICENSE
    Gene Ontology Consortium data and data products are licensed under the Creative Commons Attribution 4.0 Unported License (https://creativecommons.org/licenses/by/4.0/legalcode)
    http://geneontology.org/docs/go-citation-policy/
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