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IDH3A - isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha (domestic cattle)

Gene
Symbol
Dates
  • Create:
    2016-09-14
  • Modify:
    2025-01-19

1 Names and Identifiers

1.1 Synonyms

  • BG1
  • isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
  • NAD(+)-specific ICDH subunit alpha
  • isocitrate dehydrogenase (NAD(+)) 3 alpha
  • isocitrate dehydrogenase 3 (NAD(+)) alpha
  • isocitrate dehydrogenase 3 (NAD+) alpha
  • isocitrate dehydrogenase subunits 3/4
  • isocitric dehydrogenase subunit alpha

1.2 Other Identifiers

1.2.1 Ensembl ID

1.2.2 Enzyme Commission (EC) Number

1.2.3 GlyCosmos Gene

3 Proteins

3.1 Protein Function

Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.

3.2 Protein Targets

4 Interactions and Pathways

4.1 Pathways

5 Biochemical Reactions

6 Expression

7 Literature

7.1 Gene-Chemical Co-Occurrences in Literature

7.2 Gene-Gene Co-Occurrences in Literature

7.3 Gene-Disease Co-Occurrences in Literature

8 Patents

8.1 Gene-Chemical Co-Occurrences in Patents

8.2 Gene-Gene Co-Occurrences in Patents

8.3 Gene-Disease Co-Occurrences in Patents

9 Information Sources

  1. NCBI Gene
    LICENSE
    NCBI Website and Data Usage Policies and Disclaimers
    https://www.ncbi.nlm.nih.gov/home/about/policies/
  2. PubChem
  3. GlyCosmos Glycoscience Portal
    LICENSE
    All copyrightable parts of the datasets in GlyCosmos are under the Creative Commons Attribution (CC BY 4.0) License.
    https://glycosmos.org/license
  4. NCBI Gene Expression Omnibus (GEO)
  5. UniProt
    LICENSE
    We have chosen to apply the Creative Commons Attribution (CC BY 4.0, http://creativecommons.org/licenses/by/4.0/) License to all copyrightable parts of our databases.
    https://www.uniprot.org/help/license
  6. Rhea - annotated reactions database
    LICENSE
    Rhea has chosen to apply the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). This means that you are free to copy, distribute, display and make commercial use of the database in all legislations, provided you credit (cite) Rhea.
    https://www.rhea-db.org/help/license-disclaimer
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