Adora2a - adenosine A2a receptor (Norway rat)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-18
Description
Enables G protein-coupled adenosine receptor activity; alpha-actinin binding activity; and type 5 metabotropic glutamate receptor binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; chemical synaptic transmission; and modulation of chemical synaptic transmission. Located in several cellular components, including axolemma; intermediate filament; and presynaptic active zone. Is active in glutamatergic synapse; postsynaptic membrane; and presynaptic membrane. Used to study lung disease. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ADORA2A (adenosine A2a receptor).
- A2ar
- ADENO
- Adora2l1
- adenosine receptor A2a
- Adenosine A2a-receptor
- Adenosine A(2A) Receptor
- Adenosine A2A Receptor
- Adenosine A2A Receptors
Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PMID: 23994616).
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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