Cyp2a1 - cytochrome P450, family 2, subfamily a, polypeptide 1 (Norway rat)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-18
Description
Enables steroid hydroxylase activity. Involved in coumarin metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle.
- RATCYP2A1
- Shdl
- cytochrome P450 2A1
- CYPIIA1
- P450-UT-F
- cytochrome P450 IIA1 (hepatic steroid hydroxylase IIA1)
- cytochrome P450-UT-F
- steroid hormones 7-alpha-hydroxylase
- steroid hydroxylase, hepatic
- testosterone 7-alpha-hydroxylase
Highly active in the 7-alpha-hydroxylation of testosterone, progesterone and androstenedione.
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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