Cd48 - Cd48 molecule (Norway rat)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-17
Description
Predicted to enable receptor ligand activity. Involved in mast cell activation. Part of protein-containing complex. Orthologous to human CD48 (CD48 molecule).
- SLAMF2
- CD48 antigen
- BCM1 surface antigen
- BLAST-1
- MRC OX-45 surface antigen
- SLAM family member 2
- signaling lymphocytic activation molecule 2
- CD48 (human)
- CD48 (black-footed ferret)
- CD48 (European mink)
- CD48 (Oenanthe melanoleuca)
- CD48 (Chinese forest musk deer)
- CD48 (raccoon dog)
- CD48 (Pteronotus mesoamericanus)
- CD48 (California condor)
- CD48 (Macaca thibetana thibetana)
- CD48 (snow leopard)
- CD48 (Loggerhead turtle)
- CD48 (Eurasian river otter)
- CD48 (bobcat)
- CD48 (greater spear-nosed bat)
- CD48 (American black bear)
- CD48 (Ring-tailed lemur)
- CD48 (Komodo dragon)
- CD48 (American mink)
- CD48 (leopard cat)
- CD48 (wapiti)
- CD48 (Arctic fox)
- CD48 (rufous-necked snowfinch)
- CD48 (jaguarundi)
- CD48 (large flying fox)
- CD48 (Reeves's turtle)
- CD48 (striped hyena)
- CD48 (Jamaican fruit-eating bat)
- CD48 (Sturnira hondurensis)
- CD48 (Kuhl's pipistrelle)
- CD48 (Myotis myotis)
- CD48 (Pallas's mastiff bat)
- CD48 (pale spear-nosed bat)
- CD48 (Southern elephant seal)
- CD48 (Francois's langur)
- CD48 (greater horseshoe bat)
- CD48 (vaquita)
- CD48 (silvery gibbon)
- CD48 (Steller sea lion)
- CD48 (California sea lion)
- CD48 (brown bear)
- CD48 (Okarito brown kiwi)
- CD48 (red fox)
- CD48 (puma)
- CD48 (dingo)
- CD48 (gelada)
- CD48 (Yangtze finless porpoise)
- CD48 (common vampire bat)
- CD48 (Ugandan red Colobus)
- CD48 (beluga whale)
- CD48 (Hawaiian monk seal)
- CD48 (zebu cattle)
- CD48 (Australian saltwater crocodile)
- CD48 (leopard)
- CD48 (goat)
- CD48 (black snub-nosed monkey)
- CD48 (Malayan pangolin)
- CD48 (Panamanian white-faced capuchin)
- CD48 (Miniopterus natalensis)
- CD48 (Egyptian rousette)
- CD48 (cheetah)
- CD48 (Common starling)
- CD48 (ass)
- CD48 (gray mouse lemur)
- CD48 (Coquerel's sifaka)
- CD48 (sooty mangabey)
- CD48 (drill)
- CD48 (Colobus angolensis palliatus)
- CD48 (pig-tailed macaque)
- CD48 (large flying fox)
- CD48 (Arabian camel)
- CD48 (Bactrian camel)
- CD48 (Bison bison bison)
- CD48 (golden snub-nosed monkey)
- CD48 (speckled mousebird)
- CD48 (red-throated loon)
- CD48 (polar bear)
- CD48 (Przewalski's horse)
- CD48 (big brown bat)
- CD48 (Philippine tarsier)
- CD48 (green monkey)
- CD48 (platypus)
- CD48 (Yangtze River dolphin)
- CD48 (minke whale)
- CD48 (sperm whale)
- CD48 (tiger)
- CD48 (Green sea turtle)
- CD48 (black flying fox)
- CD48 (Myotis davidii)
- CD48 (Weddell seal)
- CD48 (American alligator)
- CD48 (alpaca)
- CD48 (Wild Bactrian camel)
- CD48 (Chinese tree shrew)
- CD48 (little brown bat)
- CD48 (water buffalo)
- CD48 (Chinese alligator)
- CD48 (wild yak)
- CD48 (Brandt's bat)
- CD48 (crab-eating macaque)
- Cd48 (long-tailed chinchilla)
- CD48 (Collared flycatcher)
- CD48 (domestic ferret)
- CD48 (small Madagascar hedgehog)
- CD48 (European shrew)
- CD48 (American pika)
- CD48 (nine-banded armadillo)
- CD48 (Pacific walrus)
- CD48 (killer whale)
- CD48 (western lowland gorilla)
- CD48 (domestic cat)
- CD48 (Bolivian squirrel monkey)
- CD48 (olive baboon)
- CD48 (pygmy chimpanzee)
- CD48 (small-eared galago)
- CD48 (African savanna elephant)
- CD48 (northern white-cheeked gibbon)
- CD48 (pig)
- CD48 (giant panda)
- CD48 (Sumatran orangutan)
- CD48 (white-tufted-ear marmoset)
- CD48 (rabbit)
- CD48 (horse)
- CD48 (Rhesus monkey)
- CD48 (domestic cattle)
- CD48 (dog)
- CD48 (chimpanzee)
- Cd48 (house mouse)
Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells.
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- PubChem
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- STRING: functional protein association networks
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- Swiss Institute of Bioinformatics Bgee
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