Abcf1 - ATP-binding cassette, sub-family F member 1 (house mouse)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-29
Description
Predicted to enable ATP binding activity; ribosome binding activity; and translation activator activity. Predicted to be involved in positive regulation of translation and translational initiation. Predicted to be located in cytosol; nucleus; and ribosome. Is expressed in several structures, including eye; genitourinary system; hemolymphoid system; lung; and nervous system. Orthologous to human ABCF1 (ATP binding cassette subfamily F member 1).
- Abc50
- D17Wsu166e
- GCN20
- ATP-binding cassette sub-family F member 1
- ATP-binding cassette, sub-family F (GCN20), member 1
Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis (By similarity).
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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