Stx3 - syntaxin 3 (house mouse)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-29
Description
Predicted to enable SNAP receptor activity; SNARE binding activity; and arachidonate binding activity. Involved in exocytic insertion of neurotransmitter receptor to postsynaptic membrane; modulation of chemical synaptic transmission; and vesicle-mediated transport in synapse. Acts upstream of or within exocytosis and long-term synaptic potentiation. Located in several cellular components, including cytoplasmic vesicle; photoreceptor inner segment; and photoreceptor outer segment. Part of SNARE complex. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in congenital diarrhea. Orthologous to human STX3 (syntaxin 3).
- Syn-3
- syntaxin-3
- Qa-SNAREs
- Syntaxin 10
- Syntaxin
- Syntaxin 11 Protein
- Syntaxin 17
- Syntaxin 3B
- Syntaxin 3C Protein
- Syntaxin 18
- Syntaxin 18 Protein
- Syntaxin 1A Homologs
- Syntaxin 10 Protein
- Syntaxin 3B Protein
- Syntaxin 11
- Syntaxin 3 Protein
- Syntaxin 13
- Syntaxin 3D Protein
- Syntaxin 13 Protein
- Syntaxin 17 Protein
- Syntaxin 3
- Syntaxin 3D
- Syntaxin 3A
- Syntaxin 4
- Syntaxin 3A Protein
- Syntaxin 4 Protein
- Syntaxin 3C
- Syntaxin 5 Protein
- Syntaxin 8
- Syntaxin 6
- Syntaxin 8 Protein
- Syntaxin 5
- Syntaxin 6 Protein
- Syntaxin 7
- Syntaxin Proteins
- Syntaxin 7 Protein
- Syntaxin Protein
- Syntaxins
Potentially involved in docking of synaptic vesicles at presynaptic active zones. Apical receptor involved in membrane fusion of apical vesicles (By similarity). Essential for survival of retinal photoreceetors (PMID: 33974130).
Isoform
UniProt ID
RefSeq Accession
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- PubChem
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- STRING: functional protein association networks
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- Swiss Institute of Bioinformatics Bgee
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