Elovl6 - ELOVL fatty acid elongase 6 (house mouse)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-29
Description
Enables acyltransferase activity, transferring groups other than amino-acyl groups. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within fatty acid elongation. Located in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human ELOVL6 (ELOVL fatty acid elongase 6).
- FAE
- LCE
- very long chain fatty acid elongase 6
- 3-keto acyl-CoA synthase Elovl6
- ELOVL FA elongase 6
- ELOVL family member 6, elongation of long chain fatty acids
- elongation of very long chain fatty acids protein 6
- fatty acyl-CoA elongase
- long chain fatty acid elongase
- long chain fatty acyl elongase
- myelin-associated SUR4 protein
- very long chain 3-ketoacyl-CoA synthase 6
- very long chain 3-oxoacyl-CoA synthase 6
- ELOVL6 (human)
- ELOVL6 (black-footed ferret)
- ELOVL6 (European mink)
- ELOVL6 (Ahaetulla prasina)
- ELOVL6 (red-backed fairy wren)
- ELOVL6 (Oenanthe melanoleuca)
- ELOVL6 (Chinese forest musk deer)
- ELOVL6 (raccoon dog)
- ELOVL6 (Leopard gecko)
- ELOVL6 (Pteronotus mesoamericanus)
- ELOVL6 (black-legged kittiwake)
- ELOVL6 (Aeolian wall lizard)
- ELOVL6 (graceful crag lizard)
- ELOVL6 (lesser prairie-chicken)
- ELOVL6 (takin)
- ELOVL6 (yellow-footed antechinus)
- ELOVL6 (California condor)
- ELOVL6 (Macaca thibetana thibetana)
- ELOVL6 (Northern goshawk)
- ELOVL6 (snow leopard)
- ELOVL6 (rock ptarmigan)
- ELOVL6 (Loggerhead turtle)
- ELOVL6 (Sphaerodactylus townsendi)
- ELOVL6 (Eurasian river otter)
- ELOVL6 (bobcat)
- ELOVL6 (greater spear-nosed bat)
- ELOVL6 (American black bear)
- ELOVL6 (Ring-tailed lemur)
- ELOVL6 (Agile Gracile Mouse Opossum)
- ELOVL6 (Komodo dragon)
- ELOVL6 (Asiatic toad)
- ELOVL6 (American mink)
- ELOVL6 (leopard cat)
- ELOVL6 (elk)
- ELOVL6 (fence lizard)
- ELOVL6 (Arctic fox)
- ELOVL6 (rufous-necked snowfinch)
- ELOVL6 (white-rumped snowfinch)
- ELOVL6 (jaguarundi)
- ELOVL6 (common toad)
- ELOVL6 (common frog)
- ELOVL6 (scimitar-horned oryx)
- ELOVL6 (Barn swallow)
- ELOVL6 (Indian flying fox)
- ELOVL6 (Eurasian tree sparrow)
- ELOVL6 (Reeves's turtle)
- ELOVL6 (Tiger rattlesnake)
- ELOVL6 (striped hyena)
- ELOVL6 (leatherback sea turtle)
- ELOVL6 (Iberian mole)
- ELOVL6 (Jamaican fruit-eating bat)
- ELOVL6 (Sturnira hondurensis)
- ELOVL6 (Kuhl's pipistrelle)
- ELOVL6 (Myotis myotis)
- ELOVL6 (Pallas's mastiff bat)
- ELOVL6 (black swan)
- ELOVL6 (common lizard)
- ELOVL6 (Southern elephant seal)
- ELOVL6 (Trachemys scripta elegans)
- ELOVL6 (Pantherophis guttatus)
- ELOVL6 (Gabon caecilian)
- ELOVL6 (Francois's langur)
- ELOVL6 (greater horseshoe bat)
- ELOVL6 (Abingdon island giant tortoise)
- ELOVL6 (vaquita)
- ELOVL6 (tufted duck)
- ELOVL6 (silvery gibbon)
- ELOVL6 (ring-necked pheasant)
- ELOVL6 (Kakapo)
- ELOVL6 (Microcaecilia unicolor)
- ELOVL6 (Aquila chrysaetos chrysaetos)
- ELOVL6 (Common wall lizard)
- ELOVL6 (pale spear-nosed bat)
- ELOVL6 (Steller sea lion)
- ELOVL6 (willow flycatcher)
- ELOVL6 (California sea lion)
- ELOVL6 (burrowing owl)
- ELOVL6 (eastern brown snake)
- ELOVL6 (mainland tiger snake)
- ELOVL6 (brown bear)
- ELOVL6 (emu)
- ELOVL6 (Okarito brown kiwi)
- ELOVL6 (Nothoprocta perdicaria)
- ELOVL6 (red fox)
- ELOVL6 (puma)
- ELOVL6 (dingo)
- ELOVL6 (gelada)
- ELOVL6 (common vampire bat)
- ELOVL6 (blue tit)
- ELOVL6 (Ugandan red Colobus)
- ELOVL6 (beluga whale)
- ELOVL6 (Hawaiian monk seal)
- ELOVL6 (white-rumped munia)
- ELOVL6 (helmeted guineafowl)
- ELOVL6 (koala)
- ELOVL6 (central bearded dragon)
- ELOVL6 (zebu cattle)
- ELOVL6 (great roundleaf bat)
- ELOVL6 (Australian saltwater crocodile)
- ELOVL6 (Gharial)
- ELOVL6 (leopard)
- ELOVL6 (Nanorana parkeri)
- ELOVL6 (black snub-nosed monkey)
- ELOVL6 (Malayan pangolin)
- ELOVL6 (Panamanian white-faced capuchin)
- ELOVL6 (Miniopterus natalensis)
- ELOVL6 (Egyptian rousette)
- ELOVL6 (Japanese quail)
- ELOVL6 (Taiwan habu)
- ELOVL6 (Great Tit)
- ELOVL6 (Gekko japonicus)
- ELOVL6 (cheetah)
- ELOVL6 (Common starling)
- ELOVL6 (ass)
- ELOVL6 (Thamnophis sirtalis)
- ELOVL6 (North Island brown kiwi)
- ELOVL6 (Swan goose)
- ELOVL6 (gray mouse lemur)
- ELOVL6 (Coquerel's sifaka)
- ELOVL6 (sooty mangabey)
- ELOVL6 (drill)
- ELOVL6 (Colobus angolensis palliatus)
- ELOVL6 (pig-tailed macaque)
- ELOVL6 (large flying fox)
- ELOVL6 (Arabian camel)
- ELOVL6 (Bactrian camel)
- ELOVL6 (Bison bison bison)
- ELOVL6 (bald eagle)
- ELOVL6 (Corvus cornix cornix)
- ELOVL6 (golden snub-nosed monkey)
- ELOVL6 (White-tailed tropicbird)
- ELOVL6 (speckled mousebird)
- ELOVL6 (brown roatelo)
- ELOVL6 (chuck-will's-widow)
- ELOVL6 (Buceros rhinoceros silvestris)
- ELOVL6 (Macqueen's bustard)
- ELOVL6 (yellow-throated sandgrouse)
- ELOVL6 (Kea)
- ELOVL6 (chimney swift)
- ELOVL6 (common barn owl)
- ELOVL6 (cuckoo roller)
- ELOVL6 (hoatzin)
- ELOVL6 (white-tailed eagle)
- ELOVL6 (Downy woodpecker)
- ELOVL6 (killdeer)
- ELOVL6 (bar-tailed trogon)
- ELOVL6 (red-throated loon)
- ELOVL6 (Red-legged seriema)
- ELOVL6 (African ostrich)
- ELOVL6 (little egret)
- ELOVL6 (Northern fulmar)
- ELOVL6 (common cuckoo)
- ELOVL6 (Dalmatian pelican)
- ELOVL6 (crested ibis)
- ELOVL6 (Adelie penguin)
- ELOVL6 (emperor penguin)
- ELOVL6 (Common canary)
- ELOVL6 (rifleman)
- ELOVL6 (carmine bee-eater)
- ELOVL6 (polar bear)
- ELOVL6 (American crow)
- ELOVL6 (Sunda flying lemur)
- ELOVL6 (Przewalski's horse)
- ELOVL6 (big brown bat)
- ELOVL6 (Philippine tarsier)
- ELOVL6 (green monkey)
- ELOVL6 (Yangtze River dolphin)
- ELOVL6 (Burmese python)
- ELOVL6 (minke whale)
- ELOVL6 (sperm whale)
- ELOVL6 (tiger)
- ELOVL6 (Green sea turtle)
- ELOVL6 (black flying fox)
- ELOVL6 (Myotis davidii)
- ELOVL6 (Weddell seal)
- ELOVL6 (American alligator)
- ELOVL6 (alpaca)
- ELOVL6 (Wild Bactrian camel)
- ELOVL6 (Chinese tree shrew)
- ELOVL6 (Chinese soft-shelled turtle)
- ELOVL6 (little brown bat)
- ELOVL6 (water buffalo)
- ELOVL6 (Chinese alligator)
- ELOVL6 (coelacanth)
- ELOVL6 (wild yak)
- ELOVL6 (Brandt's bat)
- ELOVL6 (goat)
- ELOVL6 (Tibetan ground-tit)
- ELOVL6 (rock pigeon)
- ELOVL6 (white-throated sparrow)
- ELOVL6 (Saker falcon)
- ELOVL6 (medium ground-finch)
- Elovl6 (long-tailed chinchilla)
- ELOVL6 (western painted turtle)
- ELOVL6 (crab-eating macaque)
- ELOVL6 (peregrine falcon)
- ELOVL6 (Collared flycatcher)
- ELOVL6 (mallard)
- ELOVL6 (domestic ferret)
- ELOVL6 (small Madagascar hedgehog)
- ELOVL6 (European shrew)
- ELOVL6 (American pika)
- ELOVL6 (nine-banded armadillo)
- ELOVL6 (Pacific walrus)
- ELOVL6 (killer whale)
- ELOVL6 (western lowland gorilla)
- ELOVL6 (sheep)
- ELOVL6 (domestic cat)
- ELOVL6 (Bolivian squirrel monkey)
- ELOVL6 (olive baboon)
- ELOVL6 (pygmy chimpanzee)
- ELOVL6 (small-eared galago)
- ELOVL6 (Tasmanian devil)
- ELOVL6 (platypus)
- ELOVL6 (African savanna elephant)
- ELOVL6 (northern white-cheeked gibbon)
- ELOVL6 (turkey)
- ELOVL6 (giant panda)
- ELOVL6 (Sumatran orangutan)
- ELOVL6 (white-tufted-ear marmoset)
- ELOVL6 (rabbit)
- ELOVL6 (pig)
- ELOVL6 (zebra finch)
- ELOVL6 (horse)
- ELOVL6 (Rhesus monkey)
- elovl6 (tropical clawed frog)
- ELOVL6 (domestic cattle)
- ELOVL6 (dog)
- ELOVL6 (chimpanzee)
- ELOVL6 (chicken)
- elovl6 (zebrafish)
- Elovl6 (Norway rat)
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- STRING: functional protein association networks
- Swiss Institute of Bioinformatics Bgee
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