MEI1 - meiotic double-stranded break formation protein 1 (human)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2024-12-24
Description
Predicted to be involved in meiosis I. Predicted to act upstream of or within germ cell development; meiotic nuclear division; and meiotic spindle organization. Implicated in gestational trophoblastic neoplasm.
- HYDM3
- SPATA38
- meiosis inhibitor protein 1
- meiosis defective 1
- meiosis defective protein 1
- meiosis inhibitor 1
- spermatogenesis associated 38
Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes (By similarity).
Isoform
UniProt ID
RefSeq Accession
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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