Ppp1r3a - protein phosphatase 1, regulatory subunit 3A (house mouse)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-02-02
Description
Predicted to enable glycogen binding activity; protein phosphatase 1 binding activity; and protein serine/threonine phosphatase activity. Predicted to be involved in regulation of glycogen biosynthetic process. Predicted to act upstream of or within glycogen metabolic process. Predicted to be located in membrane. Predicted to be part of protein phosphatase type 1 complex. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in hypoglycemia and type 2 diabetes mellitus. Orthologous to human PPP1R3A (protein phosphatase 1 regulatory subunit 3A).
- GM
- RG1
- RGL
- protein phosphatase 1 regulatory subunit 3A
- protein phosphatase 1 glycogen-associated regulatory subunit
- protein phosphatase 1, regulatory (inhibitor) subunit 3A
- protein phosphatase type-1 glycogen targeting subunit
- PPP1R3A (human)
- PPP1R3A (black-footed ferret)
- PPP1R3A (European mink)
- PPP1R3A (Ahaetulla prasina)
- PPP1R3A (red-backed fairy wren)
- PPP1R3A (Oenanthe melanoleuca)
- PPP1R3A (Chinese forest musk deer)
- PPP1R3A (raccoon dog)
- PPP1R3A (Leopard gecko)
- PPP1R3A (Pteronotus mesoamericanus)
- PPP1R3A (black-legged kittiwake)
- PPP1R3A (Aeolian wall lizard)
- PPP1R3A (graceful crag lizard)
- PPP1R3A (lesser prairie-chicken)
- PPP1R3A (takin)
- PPP1R3A (yellow-footed antechinus)
- PPP1R3A (California condor)
- PPP1R3A (Macaca thibetana thibetana)
- PPP1R3A (Northern goshawk)
- PPP1R3A (snow leopard)
- PPP1R3A (rock ptarmigan)
- PPP1R3A (Loggerhead turtle)
- PPP1R3A (Sphaerodactylus townsendi)
- PPP1R3A (Eurasian river otter)
- PPP1R3A (bobcat)
- PPP1R3A (greater spear-nosed bat)
- PPP1R3A (American black bear)
- PPP1R3A (Ring-tailed lemur)
- PPP1R3A (Agile Gracile Mouse Opossum)
- PPP1R3A (Komodo dragon)
- PPP1R3A (Asiatic toad)
- PPP1R3A (American mink)
- PPP1R3A (leopard cat)
- PPP1R3A (elk)
- PPP1R3A (fence lizard)
- PPP1R3A (Arctic fox)
- PPP1R3A (rufous-necked snowfinch)
- PPP1R3A (white-rumped snowfinch)
- PPP1R3A (jaguarundi)
- PPP1R3A (common toad)
- PPP1R3A (common frog)
- PPP1R3A (scimitar-horned oryx)
- PPP1R3A (Barn swallow)
- PPP1R3A (Indian flying fox)
- PPP1R3A (Eurasian tree sparrow)
- PPP1R3A (Reeves's turtle)
- PPP1R3A (striped hyena)
- PPP1R3A (leatherback sea turtle)
- PPP1R3A (Iberian mole)
- PPP1R3A (Jamaican fruit-eating bat)
- PPP1R3A (Sturnira hondurensis)
- PPP1R3A (Kuhl's pipistrelle)
- PPP1R3A (Myotis myotis)
- PPP1R3A (Pallas's mastiff bat)
- PPP1R3A (black swan)
- PPP1R3A (common lizard)
- PPP1R3A (Southern elephant seal)
- PPP1R3A (Trachemys scripta elegans)
- PPP1R3A (Pantherophis guttatus)
- PPP1R3A (Gabon caecilian)
- PPP1R3A (Francois's langur)
- PPP1R3A (greater horseshoe bat)
- PPP1R3A (Abingdon island giant tortoise)
- PPP1R3A (silvery gibbon)
- PPP1R3A (vaquita)
- PPP1R3A (tufted duck)
- PPP1R3A (ring-necked pheasant)
- PPP1R3A (Kakapo)
- PPP1R3A (Microcaecilia unicolor)
- PPP1R3A (Aquila chrysaetos chrysaetos)
- PPP1R3A (Common wall lizard)
- PPP1R3A (pale spear-nosed bat)
- PPP1R3A (Steller sea lion)
- PPP1R3A (willow flycatcher)
- PPP1R3A (California sea lion)
- PPP1R3A (burrowing owl)
- PPP1R3A (eastern brown snake)
- PPP1R3A (mainland tiger snake)
- PPP1R3A (brown bear)
- PPP1R3A (emu)
- PPP1R3A (Okarito brown kiwi)
- PPP1R3A (Nothoprocta perdicaria)
- PPP1R3A (red fox)
- PPP1R3A (puma)
- PPP1R3A (dingo)
- PPP1R3A (gelada)
- PPP1R3A (Yangtze finless porpoise)
- PPP1R3A (common vampire bat)
- PPP1R3A (blue tit)
- PPP1R3A (Ugandan red Colobus)
- PPP1R3A (beluga whale)
- PPP1R3A (Hawaiian monk seal)
- PPP1R3A (white-rumped munia)
- PPP1R3A (helmeted guineafowl)
- PPP1R3A (koala)
- PPP1R3A (central bearded dragon)
- PPP1R3A (zebu cattle)
- PPP1R3A (Australian saltwater crocodile)
- PPP1R3A (Gharial)
- PPP1R3A (leopard)
- PPP1R3A (Nanorana parkeri)
- PPP1R3A (black snub-nosed monkey)
- PPP1R3A (Malayan pangolin)
- PPP1R3A (Panamanian white-faced capuchin)
- PPP1R3A (Miniopterus natalensis)
- PPP1R3A (Egyptian rousette)
- ppp1r3ab (turquoise killifish)
- PPP1R3A (Japanese quail)
- PPP1R3A (Taiwan habu)
- PPP1R3A (Great Tit)
- PPP1R3A (Gekko japonicus)
- PPP1R3A (cheetah)
- PPP1R3A (Common starling)
- PPP1R3A (ass)
- PPP1R3A (Thamnophis sirtalis)
- PPP1R3A (North Island brown kiwi)
- PPP1R3A (Swan goose)
- PPP1R3A (gray mouse lemur)
- PPP1R3A (Coquerel's sifaka)
- PPP1R3A (sooty mangabey)
- PPP1R3A (drill)
- PPP1R3A (Colobus angolensis palliatus)
- PPP1R3A (pig-tailed macaque)
- PPP1R3A (large flying fox)
- PPP1R3A (Arabian camel)
- PPP1R3A (Bactrian camel)
- PPP1R3A (Bison bison bison)
- PPP1R3A (turkey)
- PPP1R3A (bald eagle)
- PPP1R3A (Corvus cornix cornix)
- PPP1R3A (golden snub-nosed monkey)
- PPP1R3A (White-tailed tropicbird)
- PPP1R3A (white-throated tinamou)
- PPP1R3A (speckled mousebird)
- PPP1R3A (brown roatelo)
- PPP1R3A (chuck-will's-widow)
- PPP1R3A (sunbittern)
- PPP1R3A (Buceros rhinoceros silvestris)
- PPP1R3A (Macqueen's bustard)
- PPP1R3A (yellow-throated sandgrouse)
- PPP1R3A (Kea)
- PPP1R3A (chimney swift)
- PPP1R3A (red-crested turaco)
- PPP1R3A (common barn owl)
- PPP1R3A (cuckoo roller)
- PPP1R3A (hoatzin)
- PPP1R3A (white-tailed eagle)
- PPP1R3A (Downy woodpecker)
- PPP1R3A (killdeer)
- PPP1R3A (bar-tailed trogon)
- PPP1R3A (red-throated loon)
- PPP1R3A (Red-legged seriema)
- PPP1R3A (African ostrich)
- PPP1R3A (little egret)
- PPP1R3A (Northern fulmar)
- PPP1R3A (common cuckoo)
- PPP1R3A (great cormorant)
- PPP1R3A (Dalmatian pelican)
- PPP1R3A (crested ibis)
- PPP1R3A (Adelie penguin)
- PPP1R3A (emperor penguin)
- PPP1R3A (Common canary)
- PPP1R3A (rifleman)
- PPP1R3A (carmine bee-eater)
- PPP1R3A (polar bear)
- PPP1R3A (American crow)
- PPP1R3A (Sunda flying lemur)
- PPP1R3A (Przewalski's horse)
- PPP1R3A (big brown bat)
- PPP1R3A (Philippine tarsier)
- PPP1R3A (green monkey)
- PPP1R3A (Yangtze River dolphin)
- PPP1R3A (Burmese python)
- PPP1R3A (minke whale)
- PPP1R3A (sperm whale)
- PPP1R3A (tiger)
- PPP1R3A (Green sea turtle)
- PPP1R3A (black flying fox)
- PPP1R3A (Myotis davidii)
- PPP1R3A (Weddell seal)
- PPP1R3A (American alligator)
- PPP1R3A (alpaca)
- PPP1R3A (Wild Bactrian camel)
- PPP1R3A (Chinese tree shrew)
- PPP1R3A (Chinese soft-shelled turtle)
- PPP1R3A (little brown bat)
- PPP1R3A (water buffalo)
- PPP1R3A (Chinese alligator)
- PPP1R3A (wild yak)
- PPP1R3A (Brandt's bat)
- PPP1R3A (goat)
- PPP1R3A (crab-eating macaque)
- PPP1R3A (Tibetan ground-tit)
- PPP1R3A (rock pigeon)
- PPP1R3A (white-throated sparrow)
- PPP1R3A (Saker falcon)
- PPP1R3A (medium ground-finch)
- Ppp1r3a (long-tailed chinchilla)
- PPP1R3A (western painted turtle)
- PPP1R3A (peregrine falcon)
- PPP1R3A (Collared flycatcher)
- PPP1R3A (mallard)
- PPP1R3A (chicken)
- PPP1R3A (domestic ferret)
- PPP1R3A (small Madagascar hedgehog)
- PPP1R3A (European shrew)
- PPP1R3A (American pika)
- PPP1R3A (nine-banded armadillo)
- PPP1R3A (Pacific walrus)
- PPP1R3A (killer whale)
- PPP1R3A (western lowland gorilla)
- PPP1R3A (sheep)
- PPP1R3A (domestic cat)
- PPP1R3A (Bolivian squirrel monkey)
- PPP1R3A (olive baboon)
- PPP1R3A (pygmy chimpanzee)
- PPP1R3A (small-eared galago)
- PPP1R3A (Tasmanian devil)
- PPP1R3A (African savanna elephant)
- PPP1R3A (northern white-cheeked gibbon)
- PPP1R3A (pig)
- PPP1R3A (giant panda)
- PPP1R3A (Sumatran orangutan)
- PPP1R3A (white-tufted-ear marmoset)
- PPP1R3A (zebra finch)
- PPP1R3A (platypus)
- PPP1R3A (horse)
- ppp1r3a (tropical clawed frog)
- PPP1R3A (gray short-tailed opossum)
- PPP1R3A (rabbit)
- ppp1r3ab (zebrafish)
- PPP1R3A (domestic cattle)
- PPP1R3A (Rhesus monkey)
- Ppp1r3a (Norway rat)
- PPP1R3A (dog)
- PPP1R3A (chimpanzee)
Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- PubChem
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- STRING: functional protein association networks
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- NCBI Gene Expression Omnibus (GEO)
- Swiss Institute of Bioinformatics Bgee
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