Chka - choline kinase alpha (house mouse)
- Create:2016-09-14
- Modify:2025-01-25
- CK
- CK/EK-alpha
- Chetk-alpha
- Chk
- ChoK
- EK
- EtnK-alpha
- choline/ethanolamine kinase alpha
- ethanolamine kinase
- CHKA (human)
- CHKA (black-footed ferret)
- CHKA (European mink)
- CHKA (Ahaetulla prasina)
- CHKA (red-backed fairy wren)
- CHKA (Oenanthe melanoleuca)
- CHKA (Chinese forest musk deer)
- CHKA (raccoon dog)
- CHKA (Leopard gecko)
- CHKA (Pteronotus mesoamericanus)
- CHKA (black-legged kittiwake)
- CHKA (Aeolian wall lizard)
- CHKA (graceful crag lizard)
- CHKA (lesser prairie-chicken)
- CHKA (takin)
- CHKA (yellow-footed antechinus)
- CHKA (California condor)
- CHKA (Macaca thibetana thibetana)
- CHKA (Northern goshawk)
- CHKA (snow leopard)
- CHKA (rock ptarmigan)
- CHKA (Loggerhead turtle)
- CHKA (Sphaerodactylus townsendi)
- CHKA (Eurasian river otter)
- CHKA (bobcat)
- CHKA (greater spear-nosed bat)
- CHKA (American black bear)
- CHKA (Ring-tailed lemur)
- CHKA (Agile Gracile Mouse Opossum)
- CHKA (Komodo dragon)
- CHKA (American mink)
- CHKA (leopard cat)
- CHKA (wapiti)
- CHKA (fence lizard)
- CHKA (Arctic fox)
- CHKA (rufous-necked snowfinch)
- CHKA (white-rumped snowfinch)
- CHKA (jaguarundi)
- CHKA (common toad)
- CHKA (common frog)
- CHKA (scimitar-horned oryx)
- CHKA (Barn swallow)
- CHKA (Indian flying fox)
- CHKA (Eurasian tree sparrow)
- CHKA (Reeves's turtle)
- CHKA (Tiger rattlesnake)
- CHKA (striped hyena)
- CHKA (leatherback sea turtle)
- CHKA (Iberian mole)
- CHKA (Jamaican fruit-eating bat)
- CHKA (Sturnira hondurensis)
- CHKA (Kuhl's pipistrelle)
- CHKA (Myotis myotis)
- CHKA (Pallas's mastiff bat)
- CHKA (black swan)
- CHKA (common lizard)
- CHKA (Southern elephant seal)
- CHKA (Trachemys scripta elegans)
- CHKA (Pantherophis guttatus)
- CHKA (Francois's langur)
- CHKA (greater horseshoe bat)
- CHKA (Abingdon island giant tortoise)
- CHKA (vaquita)
- CHKA (tufted duck)
- CHKA (silvery gibbon)
- CHKA (ring-necked pheasant)
- CHKA (Kakapo)
- CHKA (Aquila chrysaetos chrysaetos)
- CHKA (Common wall lizard)
- CHKA (pale spear-nosed bat)
- CHKA (Steller sea lion)
- CHKA (willow flycatcher)
- CHKA (California sea lion)
- CHKA (burrowing owl)
- CHKA (eastern brown snake)
- CHKA (mainland tiger snake)
- CHKA (brown bear)
- CHKA (emu)
- CHKA (Okarito brown kiwi)
- CHKA (Nothoprocta perdicaria)
- CHKA (red fox)
- CHKA (puma)
- CHKA (dingo)
- CHKA (gelada)
- CHKA (Yangtze finless porpoise)
- CHKA (common vampire bat)
- CHKA (blue tit)
- CHKA (Ugandan red Colobus)
- CHKA (beluga whale)
- CHKA (Hawaiian monk seal)
- CHKA (white-rumped munia)
- CHKA (helmeted guineafowl)
- CHKA (koala)
- CHKA (central bearded dragon)
- CHKA (zebu cattle)
- CHKA (great roundleaf bat)
- CHKA (Australian saltwater crocodile)
- CHKA (Gharial)
- CHKA (leopard)
- CHKA (western lowland gorilla)
- CHKA (Nanorana parkeri)
- CHKA (black snub-nosed monkey)
- CHKA (Malayan pangolin)
- CHKA (Panamanian white-faced capuchin)
- CHKA (Miniopterus natalensis)
- CHKA (Egyptian rousette)
- CHKA (Japanese quail)
- CHKA (Taiwan habu)
- CHKA (Great Tit)
- CHKA (Gekko japonicus)
- CHKA (cheetah)
- CHKA (Common starling)
- CHKA (ass)
- CHKA (Thamnophis sirtalis)
- CHKA (North Island brown kiwi)
- CHKA (Swan goose)
- CHKA (Coquerel's sifaka)
- CHKA (sooty mangabey)
- CHKA (drill)
- CHKA (Colobus angolensis palliatus)
- CHKA (pig-tailed macaque)
- CHKA (large flying fox)
- CHKA (Arabian camel)
- CHKA (Bactrian camel)
- CHKA (Bison bison bison)
- CHKA (bald eagle)
- CHKA (Corvus cornix cornix)
- CHKA (golden snub-nosed monkey)
- CHKA (East African grey crowned-crane)
- CHKA (White-tailed tropicbird)
- CHKA (speckled mousebird)
- CHKA (brown roatelo)
- CHKA (chuck-will's-widow)
- CHKA (sunbittern)
- CHKA (Macqueen's bustard)
- CHKA (yellow-throated sandgrouse)
- CHKA (Kea)
- CHKA (chimney swift)
- CHKA (red-crested turaco)
- CHKA (common barn owl)
- CHKA (cuckoo roller)
- CHKA (hoatzin)
- CHKA (white-tailed eagle)
- CHKA (Downy woodpecker)
- CHKA (killdeer)
- CHKA (bar-tailed trogon)
- CHKA (red-throated loon)
- CHKA (Red-legged seriema)
- CHKA (African ostrich)
- CHKA (little egret)
- CHKA (Northern fulmar)
- CHKA (common cuckoo)
- CHKA (great cormorant)
- CHKA (Dalmatian pelican)
- CHKA (crested ibis)
- CHKA (Adelie penguin)
- CHKA (emperor penguin)
- CHKA (Common canary)
- CHKA (rifleman)
- CHKA (carmine bee-eater)
- CHKA (polar bear)
- CHKA (American crow)
- CHKA (Sunda flying lemur)
- CHKA (Przewalski's horse)
- CHKA (big brown bat)
- CHKA (Philippine tarsier)
- CHKA (green monkey)
- CHKA (Yangtze River dolphin)
- CHKA (Burmese python)
- CHKA (minke whale)
- CHKA (sperm whale)
- CHKA (tiger)
- CHKA (Green sea turtle)
- CHKA (black flying fox)
- CHKA (Myotis davidii)
- CHKA (Weddell seal)
- CHKA (American alligator)
- CHKA (alpaca)
- CHKA (Wild Bactrian camel)
- CHKA (Chinese tree shrew)
- CHKA (Chinese soft-shelled turtle)
- CHKA (little brown bat)
- CHKA (water buffalo)
- CHKA (Chinese alligator)
- CHKA (wild yak)
- CHKA (Brandt's bat)
- CHKA (goat)
- CHKA (crab-eating macaque)
- CHKA (Tibetan ground-tit)
- CHKA (rock pigeon)
- CHKA (white-throated sparrow)
- CHKA (Saker falcon)
- CHKA (medium ground-finch)
- Chka (long-tailed chinchilla)
- CHKA (peregrine falcon)
- CHKA (Collared flycatcher)
- CHKA (mallard)
- CHKA (domestic ferret)
- CHKA (small Madagascar hedgehog)
- CHKA (European shrew)
- CHKA (American pika)
- CHKA (nine-banded armadillo)
- CHKA (Pacific walrus)
- CHKA (killer whale)
- CHKA (sheep)
- CHKA (domestic cat)
- CHKA (Bolivian squirrel monkey)
- CHKA (olive baboon)
- CHKA (pygmy chimpanzee)
- CHKA (small-eared galago)
- CHKA (Tasmanian devil)
- CHKA (African savanna elephant)
- CHKA (northern white-cheeked gibbon)
- CHKA (turkey)
- CHKA (pig)
- CHKA (giant panda)
- CHKA (Sumatran orangutan)
- CHKA (white-tufted-ear marmoset)
- CHKA (zebra finch)
- CHKA (horse)
- CHKA (gray short-tailed opossum)
- CHKA (Rhesus monkey)
- CHKA (domestic cattle)
- CHKA (dog)
- CHKA (chimpanzee)
- CHKA (chicken)
- Chka (Norway rat)
Plays a key role in phospholipid biosynthesis by catalyzing the phosphorylation of free choline to phosphocholine, the first step in phosphatidylcholine biosynthesis. Also phosphorylates ethanolamine, thereby contributing to phosphatidylethanolamine biosynthesis. Has higher activity with choline.
This isoform plays a key role in lipolysis of lipid droplets following glucose deprivation (By similarity). In response to glucose deprivation, phosphorylated by AMPK, promoting localization to lipid droplets (By similarity). Phosphorylation is followed by acetylation by KAT5, leading to dissociation of the homodimer into a monomer (By similarity). Monomeric CHKA isoform 1 is converted into a tyrosine-protein kinase, which phosphorylates lipid droplet structural proteins PLIN2 and PLIN3, leading to lipolysis of lipid droplets (By similarity).
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