Prdx5 - peroxiredoxin 5 (Norway rat)
Gene
Symbol
Taxonomy
Dates
- Create:2016-09-14
- Modify:2025-01-18
Description
Predicted to enable several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; identical protein binding activity; and peroxidase activity. Predicted to be involved in several processes, including NADPH oxidation; cell redox homeostasis; and regulation of apoptotic process. Located in mitochondrion and peroxisome. Orthologous to human PRDX5 (peroxiredoxin 5).
- Aoeb166
- peroxiredoxin-5, mitochondrial
- PLP
- antioxidant enzyme B166
- peroxiredoxin V
- peroxisomal antioxidant enzyme
- prx-V
- thioredoxin peroxidase PMP20
- thioredoxin reductase
- thioredoxin-dependent peroxiredoxin 5
- Alkylhydroperoxide Reductase
- Alkyl Hydroperoxide Reductase
- Alkyl Hydroperoxide Reductase C
- Alkyl Hydroperoxide Reductase D
- Peroxidoxin
- Peroxiredoxin I
- Peroxiredoxin
- Peroxiredoxin 4
- Peroxiredoxin IV
- Peroxiredoxin 5
- Peroxiredoxin II
- Peroxiredoxin V
- Peroxiredoxin-4
- Peroxiredoxin 1
- Peroxiredoxin 2
- Protector Protein (Mixed-Function Oxidase Systems)
- Thiol-Specific Antioxidant Protein
- Thioredoxin Peroxidase
- Thioredoxin-Dependent Peroxide Reductase 1
- Thioredoxin Peroxidase 2
- Thioredoxin Peroxidase 1
- Thioredoxin-Dependent Peroxide Reductase 2
- Thioredoxin Peroxidase PMP20
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Isoform
UniProt ID
RefSeq Accession
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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- PubChem
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