Ext1 - exostosin glycosyltransferase 1 (Chinese hamster)
Gene
Symbol
Dates
- Create:2016-09-14
- Modify:2025-01-17
Description
Please note that currently there is no data available in PubChem associated with Ext1 - exostosin glycosyltransferase 1 (Chinese hamster). However, annotations from external sources are available.
- exostosin-1
- Heparan sulfate copolymerase
- Multiple exostoses protein 1 homolog
- N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
- exostoses (multiple) 1
- exostosin 1
- EXT1 Heparan Sulfate Copolymerase
- Exostosin-1
- Heparan Sulfate Copolymerase EXT1
- Multiple Exostoses Protein 1
- EXT1 (human)
- EXT1 (black-footed ferret)
- EXT1 (European mink)
- EXT1 (Ahaetulla prasina)
- EXT1 (red-backed fairy wren)
- EXT1 (Oenanthe melanoleuca)
- EXT1 (Chinese forest musk deer)
- EXT1 (raccoon dog)
- EXT1 (Leopard gecko)
- EXT1 (Pteronotus mesoamericanus)
- EXT1 (black-legged kittiwake)
- EXT1 (Aeolian wall lizard)
- EXT1 (graceful crag lizard)
- EXT1 (lesser prairie-chicken)
- EXT1 (takin)
- EXT1 (yellow-footed antechinus)
- Ext1 (desert hamster)
- EXT1 (California condor)
- EXT1 (Macaca thibetana thibetana)
- Ext1 (reed vole)
- EXT1 (Northern goshawk)
- EXT1 (snow leopard)
- EXT1 (rock ptarmigan)
- EXT1 (Loggerhead turtle)
- EXT1 (Sphaerodactylus townsendi)
- Ext1 (Pacific pocket mouse)
- EXT1 (Eurasian river otter)
- Ext1 (gray squirrel)
- EXT1 (bobcat)
- EXT1 (greater spear-nosed bat)
- EXT1 (American black bear)
- EXT1 (Ring-tailed lemur)
- EXT1 (Agile Gracile Mouse Opossum)
- EXT1 (Komodo dragon)
- EXT1 (Asiatic toad)
- EXT1 (American mink)
- EXT1 (leopard cat)
- EXT1 (wapiti)
- Ext1 (banner-tailed kangaroo rat)
- EXT1 (fence lizard)
- EXT1 (Arctic fox)
- Ext1 (creeping vole)
- EXT1 (rufous-necked snowfinch)
- EXT1 (white-rumped snowfinch)
- EXT1 (jaguarundi)
- EXT1 (common toad)
- EXT1 (common frog)
- EXT1 (scimitar-horned oryx)
- EXT1 (Barn swallow)
- EXT1 (large flying fox)
- EXT1 (Eurasian tree sparrow)
- EXT1 (Reeves's turtle)
- EXT1 (Tiger rattlesnake)
- EXT1 (striped hyena)
- EXT1 (leatherback sea turtle)
- Ext1 (Eurasian water vole)
- EXT1 (Iberian mole)
- EXT1 (Jamaican fruit-eating bat)
- EXT1 (Sturnira hondurensis)
- EXT1 (Kuhl's pipistrelle)
- EXT1 (Myotis myotis)
- EXT1 (Pallas's mastiff bat)
- EXT1 (black swan)
- EXT1 (common lizard)
- EXT1 (Southern elephant seal)
- EXT1 (Trachemys scripta elegans)
- EXT1 (Pantherophis guttatus)
- EXT1 (Gaboon caecilian)
- EXT1 (Francois's langur)
- EXT1 (greater horseshoe bat)
- EXT1 (Abingdon island giant tortoise)
- EXT1 (silvery gibbon)
- EXT1 (vaquita)
- EXT1 (tufted duck)
- EXT1 (ring-necked pheasant)
- Ext1 (southern multimammate mouse)
- EXT1 (Kakapo)
- EXT1 (Microcaecilia unicolor)
- EXT1 (Aquila chrysaetos chrysaetos)
- Ext1 (white-footed mouse)
- EXT1 (Common wall lizard)
- EXT1 (pale spear-nosed bat)
- EXT1 (Steller sea lion)
- EXT1 (willow flycatcher)
- EXT1 (California sea lion)
- EXT1 (burrowing owl)
- EXT1 (eastern brown snake)
- EXT1 (mainland tiger snake)
- EXT1 (brown bear)
- EXT1 (emu)
- EXT1 (Okarito brown kiwi)
- EXT1 (Nothoprocta perdicaria)
- EXT1 (red fox)
- EXT1 (puma)
- EXT1 (dingo)
- EXT1 (gelada)
- EXT1 (Yangtze finless porpoise)
- EXT1 (common vampire bat)
- EXT1 (blue tit)
- EXT1 (Ugandan red Colobus)
- EXT1 (beluga whale)
- EXT1 (Hawaiian monk seal)
- EXT1 (white-rumped munia)
- EXT1 (helmeted guineafowl)
- Ext1 (shrew mouse)
- Ext1 (Ryukyu mouse)
- EXT1 (koala)
- EXT1 (central bearded dragon)
- EXT1 (zebu cattle)
- EXT1 (Australian saltwater crocodile)
- EXT1 (Gharial)
- EXT1 (leopard)
- EXT1 (western lowland gorilla)
- EXT1 (Nanorana parkeri)
- EXT1 (black snub-nosed monkey)
- EXT1 (Malayan pangolin)
- EXT1 (Panamanian white-faced capuchin)
- EXT1 (chimpanzee)
- EXT1 (Miniopterus natalensis)
- EXT1 (Egyptian rousette)
- EXT1 (Japanese quail)
- EXT1 (Great Tit)
- EXT1 (cheetah)
- EXT1 (Common starling)
- EXT1 (ass)
- EXT1 (North Island brown kiwi)
- EXT1 (Swan goose)
- Ext1 (Ord's kangaroo rat)
- EXT1 (gray mouse lemur)
- EXT1 (Coquerel's sifaka)
- EXT1 (sooty mangabey)
- EXT1 (Colobus angolensis palliatus)
- EXT1 (pig-tailed macaque)
- EXT1 (large flying fox)
- EXT1 (Arabian camel)
- EXT1 (Bactrian camel)
- EXT1 (Bison bison bison)
- EXT1 (bald eagle)
- EXT1 (Corvus cornix cornix)
- EXT1 (golden snub-nosed monkey)
- EXT1 (East African grey crowned-crane)
- EXT1 (white-throated tinamou)
- EXT1 (speckled mousebird)
- EXT1 (sunbittern)
- EXT1 (Buceros rhinoceros silvestris)
- EXT1 (Kea)
- EXT1 (chimney swift)
- EXT1 (common barn owl)
- EXT1 (cuckoo roller)
- EXT1 (hoatzin)
- EXT1 (Downy woodpecker)
- EXT1 (killdeer)
- EXT1 (bar-tailed trogon)
- EXT1 (red-throated loon)
- EXT1 (Red-legged seriema)
- EXT1 (African ostrich)
- EXT1 (Northern fulmar)
- EXT1 (common cuckoo)
- EXT1 (great cormorant)
- EXT1 (crested ibis)
- EXT1 (Adelie penguin)
- EXT1 (emperor penguin)
- EXT1 (Common canary)
- EXT1 (rifleman)
- Ext1 (Upper Galilee mountains blind mole rat)
- EXT1 (polar bear)
- EXT1 (American crow)
- EXT1 (Sunda flying lemur)
- EXT1 (Przewalski's horse)
- EXT1 (big brown bat)
- EXT1 (green monkey)
- EXT1 (Yangtze River dolphin)
- EXT1 (minke whale)
- EXT1 (sperm whale)
- EXT1 (tiger)
- EXT1 (Green sea turtle)
- EXT1 (black flying fox)
- EXT1 (Myotis davidii)
- EXT1 (Weddell seal)
- EXT1 (American alligator)
- EXT1 (alpaca)
- EXT1 (Wild Bactrian camel)
- EXT1 (Chinese tree shrew)
- EXT1 (Chinese soft-shelled turtle)
- EXT1 (little brown bat)
- EXT1 (water buffalo)
- EXT1 (Chinese alligator)
- EXT1 (wild yak)
- EXT1 (Brandt's bat)
- EXT1 (goat)
- EXT1 (Tibetan ground-tit)
- EXT1 (rock pigeon)
- EXT1 (white-throated sparrow)
- EXT1 (Saker falcon)
- Ext1 (long-tailed chinchilla)
- EXT1 (western painted turtle)
- EXT1 (crab-eating macaque)
- EXT1 (peregrine falcon)
- Ext1 (golden hamster)
- EXT1 (Collared flycatcher)
- EXT1 (mallard)
- Ext1 (naked mole-rat)
- EXT1 (domestic ferret)
- EXT1 (small Madagascar hedgehog)
- EXT1 (European shrew)
- EXT1 (American pika)
- EXT1 (nine-banded armadillo)
- EXT1 (Pacific walrus)
- EXT1 (Florida manatee)
- EXT1 (killer whale)
- EXT1 (sheep)
- EXT1 (domestic cat)
- EXT1 (Bolivian squirrel monkey)
- EXT1 (pygmy chimpanzee)
- EXT1 (small-eared galago)
- EXT1 (Tasmanian devil)
- EXT1 (chicken)
- Ext1 (domestic guinea pig)
- EXT1 (African savanna elephant)
- EXT1 (northern white-cheeked gibbon)
- ext1 (green anole)
- EXT1 (turkey)
- EXT1 (giant panda)
- EXT1 (white-tufted-ear marmoset)
- EXT1 (rabbit)
- EXT1 (zebra finch)
- EXT1 (Sumatran orangutan)
- EXT1 (pig)
- EXT1 (olive baboon)
- EXT1 (platypus)
- EXT1 (horse)
- EXT1 (gray short-tailed opossum)
- EXT1 (Rhesus monkey)
- EXT1 (domestic cattle)
- EXT1 (dog)
- ext1 (tropical clawed frog)
- Ext1 (Norway rat)
- Ext1 (house mouse)
Glycosyltransferase forming with EXT2 the heterodimeric heparan sulfate polymerase which catalyzes the elongation of the heparan sulfate glycan backbone. Glycan backbone extension consists in the alternating transfer of (1->4)-beta-D-GlcA and (1->4)-alpha-D-GlcNAc residues from their respective UDP-sugar donors. Both EXT1 and EXT2 are required for the full activity of the polymerase since EXT1 bears the N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity within the complex while EXT2 carries the glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Heparan sulfate proteoglycans are ubiquitous components of the extracellular matrix and play an important role in tissue homeostasis and signaling.
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