Technetium Tc-99m sestamibi
- Technetium Tc-99m sestamibi
- Technetium Tc 99m Sestamibi
- 109581-73-9
- 971Z4W1S09
- 99mTc-sestamibi
- Technetium Tc-99m sestamibi
- Technetium Tc 99m Sestamibi
- 109581-73-9
- 971Z4W1S09
- 99mTc-sestamibi
- Sestamibi
- Technetium (99m Tc) sestamibi
- 99mTc sestamibi
- 99m Tc-sestamibi
- 99m-Tc sestamibi
- 99mTc Hexamibi
- DTXCID501475550
- DTXSID00911248
- TC99M RP-30A
- TC99M-RP-30A
- Tc 99m Methoxy 2 isobutylisonitrile
- Tc 99m Sestamibi
- Tc-99m MIBI
- Tc99m Sestamibi
- Technetium Tc 99m 2 Methoxy 2 methylpropylisonitrile
- Technetium Tc 99m 2-Methoxy-2-methylpropylisonitrile
- Technetium-99m-Hexamibi
- Technetium-99m-Sestamibi
◉ Summary of Use during Lactation
Information in this record refers to the use of technetium Tc 99m sestamibi (Tc 99m-methoxyisobutylisonitrile; Tc 99m MIBI) as a diagnostic agent. A US Nuclear Regulatory Commission subcommittee has recommended that nursing be discontinued for 24 hours after administration of all technetium Tc 99m diagnostic products to simplify guidance recommendations, although this time interval may be longer than necessary. Other experts state that breastfeeding need not be interrupted after administration of technetium Tc 99m sestamibi in doses up to 1000 MBq (27 mCi) to a nursing mother. However, to follow the principle of keeping exposure "as low as reasonably achievable", some experts recommend nursing the infant just before administration of the radiopharmaceutical and interrupting breastfeeding for 3 to 4 hours after the dose, then expressing the milk completely once and discarding it. If the mother has expressed and saved milk prior to the examination, she can feed it to the infant during the period of nursing interruption. Mothers need not refrain from close contact with their infants after usual clinical doses.
Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital. When the radioactivity is at a safe level, she may resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.
For nursing mothers who work with Tc 99m substances in their workplace, there is no need to take any precautions other than those appropriate for general radiation protection.
◉ Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
◉ Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
- PubChem
- ChemIDplusTechnetium Tc 99m sestamibi [USAN:USP:INN:BAN]https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0109581739
- DrugBankLICENSECreative Common's Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/legalcode)https://www.drugbank.ca/legal/terms_of_useTechnetium Tc-99m sestamibihttps://www.drugbank.ca/drugs/DB09161
- EPA DSSToxTechnetium Tc 99m sestamibihttps://comptox.epa.gov/dashboard/DTXSID00911248
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- DailyMedTECHNETIUM TC-99M SESTAMIBIhttps://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=TECHNETIUM+TC-99M+SESTAMIBI
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- Drugs and Lactation Database (LactMed)Technetium Tc 99m Sestamibihttps://www.ncbi.nlm.nih.gov/books/n/lactmed/LM688/
- National Drug Code (NDC) DirectoryLICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linkingTECHNETIUM TC 99M SESTAMIBIhttps://www.fda.gov/drugs/drug-approvals-and-databases/national-drug-code-directory