Antagonist activity at human GPR43 expressed in U2OS cells by BacMam FLIPR/summary (Abse5) assay
- Deposit:2016-05-21
- Modify:2018-10-05
Title: Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
Abstract: The exploration of a diarylsulfonamide series of free fatty acid receptor 4 (FFA4/GPR120) agonists is described. This work led to the identification of selective FFA4 agonist 8 (GSK137647A) and selective FFA4 antagonist 39. The in vitro profile of compounds 8 and 39 is presented herein.
Journal: Bioorg Med Chem Lett
Year: 2014
Volume: 24
Issue: 14
First Page: 3100
Last Page: 3103
DOI: 10.1016/j.bmcl.2014.05.012
Target ChEMBL ID: CHEMBL5493
ChEMBL Target Name: Free fatty acid receptor 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
- PubChem
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