malT - DNA-binding transcriptional activator MalT (Escherichia coli str. K-12 substr. MG1655)
Gene
Symbol
Dates
- Create:2016-09-14
- Modify:2025-01-14
Description
Activated by maltotriose and ATP to form active oligomers. [More information is available at EcoGene: EG10562]. The malT gene is located upstream of and in the opposite direction of the operon malPQ . [More information is available at EcoCyc: EG10562].
- ECK3405
- malA
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides (PMID: 2524384, PMID: 2538630, PMID: 3305511, PMID: 7040340). Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box (5'-GGA[TG]GA-3') (PMID: 2524384, PMID: 2538630). Displays weak ATPase activity, but this activity is not required for promoter binding (PMID: 2524384).
Highly accurate protein structure prediction with AlphaFold. Nature. 2021 Aug;596(7873):583-589. DOI:10.1038/s41586-021-03819-2. PMID:34265844; PMCID:PMC8371605
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