Pregnenolone
- pregnenolone
- 145-13-1
- 3beta-Hydroxypregn-5-en-20-one
- Arthenolone
- Pregnetan
- Create:2005-06-01
- Modify:2025-01-18
- 5 Pregnen 3 beta ol 20 one
- 5-Pregnen-3-beta-ol-20-one
- Pregnenolone
- pregnenolone
- 145-13-1
- 3beta-Hydroxypregn-5-en-20-one
- Arthenolone
- Pregnetan
- Pregneton
- Pregnolon
- Prenolon
- Regnosone
- Skinostelon
- Enelone
- 5-Pregnen-3beta-ol-20-one
- Natolone
- Bina-Skin
- delta5-Pregnenolone
- 5-Pregnen-3-beta-ol-20-one
- (3BETA)-3-HYDROXYPREGN-5-EN-20-ONE
- 5-Pregnenolone
- 3-beta-Hydroxypregn-5-en-20-one
- NSC 1616
- Prestwick_859
- 3beta-Hydroxy-5-pregnen-20-one
- Pregn-5-en-20-one, 3-hydroxy-, (3beta)-
- Prestwick3_000546
- Pregnenolone (JAN/INN)
- Pregn-5-en-20-one, 3beta-hydroxy-
- 1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
- DTXSID1036541
- Pregn-5-ene-3beta-ol-20-one
- CHEBI:16581
- 73R90F7MQ8
- 3.beta.-Hydroxypregn-5-en-20-one
- MFCD00003628
- Pregnenolone (3beta-Hydroxypregn-5-en-20-one)
- 5-Pregnen-3beta;-ol-20-one
- DTXCID9016541
- Pregnenolonum
- Pregnenolone [INN:BAN]
- Pregnenolonum [INN-Latin]
- Pregnenolona [INN-Spanish]
- PLO
- SMR000112161
- .DELTA.5-Pregnenolone
- SR-05000002128
- EINECS 205-647-4
- 5-Pregnen-3.beta.-ol-20-one
- Pregnolone
- NSC-1616
- UNII-73R90F7MQ8
- NSC-18158
- Pregn-5-en-20-one, 3-hydroxy-, (3b)-
- Pregn-5-en-20-one, 3-hydroxy-, (3-beta)-
- NCGC00163125-02
- Pregn-5-en-20-one, 3.beta.-hydroxy-
- CAS-145-13-1
- Pregn-5-en-20-one, 3-beta-hydroxy-
- Pregnenolone (Standard)
- Prestwick0_000546
- Prestwick1_000546
- Prestwick2_000546
- Spectrum5_002057
- PREGNENOLONE [MI]
- PREGNENOLONE [INN]
- PREGNENOLONE [JAN]
- bmse000476
- 5-Pregnen-3b-ol-20-one
- PREGNENOLONE [VANDF]
- BIDD:PXR0019
- BSPBio_000591
- MLS002153868
- MLS002207138
- Pregn-5-en-3b-ol-20-one
- PREGNENOLONE [WHO-DD]
- SCHEMBL129572
- Pregn-5-ene-3b-ol-20-one
- SPBio_002512
- 3-Hydroxy-5-pregnen-20-one
- 3b-Hydroxypregn-5-en-20-one
- BPBio1_000651
- CHEMBL253363
- GTPL2376
- Pregn-5-en-3beta-ol-20-one
- HY-B0151R
- delta5-Pregnen-3beta-ol-20-one
- 3beta-Hydroxy-5-pregenen-20-one
- 3beta-Hydroxy-5-pregnene-20-one
- 3beta-hydroxypregn-5-ene-20-one
- HMS1569N13
- HMS2090J15
- HMS2096N13
- HMS2268A04
- HMS3713N13
- HMS3884G16
- Delta5-Pregenen-3beta-ol-20-one
- Delta5-Pregnene-3beta-ol-20-one
- 1-[(3S,8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-hydroxy-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
- BCP23361
- HY-B0151
- Tox21_112011
- Tox21_302141
- BDBM50375319
- CMC_13393
- LMST02030088
- Pregnenolone (progesterone precursor)
- s1914
- 3beta-Hydroxy-delta5-pregnen-20-one
- AKOS015841076
- AKOS015895418
- Tox21_112011_1
- (3b)-3-hydroxy-Pregn-5-en-20-one
- CCG-220546
- CS-1970
- DB02789
- DS-7794
- Pregnenolone 0.1 mg/ml in Acetonitrile
- .DELTA.5-Pregnen-3.beta.-ol-20-one
- 5-Pregnen-3beta-ol-20-one, >=98%
- NCGC00163125-03
- NCGC00163125-04
- NCGC00163125-06
- NCGC00255436-01
- AC-12806
- AC-32630
- BCP0726000217
- 3-Hydroxypregn-5-en-20-one, (3.beta.)-
- 3.beta.-Hydroxy-.DELTA.5-pregnen-20-one
- NS00014904
- P0786
- (3alpha,8alpha)-3-hydroxypregn-5-en-20-one
- C01953
- D00143
- 17beta-[1-Ketoethyl]-Delta5-androsten-3beta-ol
- EN300-7388669
- Pregn-5-en-20-one, 3-hydroxy-, (3.beta.)-
- Q412158
- J-008059
- SR-05000002128-4
- SR-05000002128-5
- .DELTA. SUP(5)-PREGNEN-3.BETA.-OL-20-ONE
- BRD-K43880410-001-14-4
- 0F6367C4-E1FA-4AEC-9846-7BCC5ADA3417
- Z2235801892
- PREGN-5-EN-20-ONE, 3-(3-CARBOXY-, (3.BETA.)-
- 17.BETA.-(1-KETOETHYL)-.DELTA. SUP(5)-ANDROSTEN-3.BETA.-OL
- 1-((3S,8S,10R,13S,17S)-3-Hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-ethanone
- 1-((3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one
- 1-[(1S,3aS,3bS,7S,9aR,9bS,11aS)-7-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]ethan-1-one
- 1-[(3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)]ethanone
172.95 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
178.26 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
180.92 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
174.28 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
171.8 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
175.44 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
216.16 Ų [M+Na]+ [CCS Type: DT; Method: stepped-field]
177.25 Ų [M+H]+ [CCS Type: DT; Method: stepped-field]
182.86 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
174 Ų [M+H]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
176.1 Ų [M+H]+
214.8 Ų [M+Na]+
316.0 99.99
283.0 76
231.0 71.30
213.0 39.10
187.0 39
316 99.99
283 76
231 71.30
213 39.10
187 39
- Prasterone; pregnenolone; progesterone (component of)
- Prasterone; pregnenolone; progesterone; testosterone (component of)
- Adrenal Cortex
- Adrenal Gland
- Brain
- Kidney
- Neuron
- Ovary
- Placenta
- Testis
- Cytoplasm
- Endoplasmic reticulum
- Extracellular
- Membrane
- Mitochondria
- 11-beta-hydroxylase deficiency (CYP11B1)
- 17-alpha-hydroxylase deficiency (CYP17)
- 21-hydroxylase deficiency (CYP21)
- 3-Beta-Hydroxysteroid Dehydrogenase Deficiency
- Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia due to 21-hydroxylase Deficiency
- Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia due to 17 Alpha-hydroxylase Deficiency
- Apparent mineralocorticoid excess syndrome
- Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH
- Corticosterone methyl oxidase I deficiency (CMO I)
- Corticosterone methyl oxidase II deficiency - CMO II
- Total 11 pathways, visit the HMDB page for details
H302 (87%): Harmful if swallowed [Warning Acute toxicity, oral]
H312 (87%): Harmful in contact with skin [Warning Acute toxicity, dermal]
H332 (87%): Harmful if inhaled [Warning Acute toxicity, inhalation]
H351 (87%): Suspected of causing cancer [Warning Carcinogenicity]
H361 (87%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
P203, P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P318, P321, P330, P362+P364, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)
Aggregated GHS information provided per 23 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Reported as not meeting GHS hazard criteria per 3 of 23 reports by companies. For more detailed information, please visit ECHA C&L website.
There are 2 notifications provided by 20 of 23 reports by companies with hazard statement code(s).
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.
Acute Tox. 4 (87%)
Acute Tox. 4 (87%)
Acute Tox. 4 (87%)
Carc. 2 (87%)
Repr. 2 (87%)
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=ORNBQBCIOKFOEO-QGVNFLHTSA-N
- CAS Common ChemistryLICENSEThe data from CAS Common Chemistry is provided under a CC-BY-NC 4.0 license, unless otherwise stated.https://creativecommons.org/licenses/by-nc/4.0/
- ChemIDplusPregnenolone [INN:BAN]https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0000145131ChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
- DrugBankLICENSECreative Common's Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/legalcode)https://www.drugbank.ca/legal/terms_of_usePregnenolonehttps://www.drugbank.ca/drugs/DB02789
- EPA DSSToxPregnenolonehttps://comptox.epa.gov/dashboard/DTXSID1036541CompTox Chemicals Dashboard Chemical Listshttps://comptox.epa.gov/dashboard/chemical-lists/
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- CCSbaseCCSbase Classificationhttps://ccsbase.net/
- NORMAN Suspect List ExchangeLICENSEData: CC-BY 4.0; Code (hosted by ECI, LCSB): Artistic-2.0https://creativecommons.org/licenses/by/4.0/PregnenoloneNORMAN Suspect List Exchange Classificationhttps://www.norman-network.com/nds/SLE/
- ChEBI
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- Therapeutic Target Database (TTD)Pregnenolonehttps://idrblab.net/ttd/data/drug/details/D0B4RU
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- ECI Group, LCSB, University of LuxembourgPregnenolone
- Natural Product Activity and Species Source (NPASS)
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- SpectraBasePregnenolonehttps://spectrabase.com/spectrum/CYlhRSzCgthPregnenolonehttps://spectrabase.com/spectrum/AIDVqRR4gBAPregnenolonehttps://spectrabase.com/spectrum/pet7gubcsRPregnenolonehttps://spectrabase.com/spectrum/Acleg1GWeXiPregnenolonehttps://spectrabase.com/spectrum/JCUBKiO90UYPregnenolonehttps://spectrabase.com/spectrum/rzp6bYDXCYPregnenolonehttps://spectrabase.com/spectrum/L3h0LyPQc8JPregnenolonehttps://spectrabase.com/spectrum/MIf9IyAR2OPregnenolonehttps://spectrabase.com/spectrum/Jj0vCXjhnkWPregnenolonehttps://spectrabase.com/spectrum/KoUDSQDiFBQ
- Japan Chemical Substance Dictionary (Nikkaji)
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- Metabolomics Workbench
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- Springer Nature
- SpringerMaterials1-((3S,8S,10R,13S,17S)-3-Hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-ethanonehttps://materials.springer.com/substanceprofile/docs/smsid_atjubwkftxcqmvrf
- The Cambridge Structural Database
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- Wikidatapregnenolonehttps://www.wikidata.org/wiki/Q412158
- WikipediaTetraamminecopper(II) sulfatehttps://en.wikipedia.org/wiki/Tetraamminecopper(II)_sulfatePregnenolonehttps://en.wikipedia.org/wiki/Pregnenolone
- Wiley
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- PubChem
- GHS Classification (UNECE)GHS Classification Treehttp://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html
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- PATENTSCOPE (WIPO)SID 403421534https://pubchem.ncbi.nlm.nih.gov/substance/403421534