Chloroquine Phosphate
- Chloroquine diphosphate
- Chloroquine phosphate
- 50-63-5
- Resochin
- Arechin
- Create:2005-06-24
- Modify:2025-01-25
- arechin
- chingamin phosphate
- chloroquine bis(dihydrogenphosphate) dihydrate
- chloroquine diphosphate
- chloroquine diphosphate, (+)-isomer
- chloroquine diphosphate, (+-)-isomer
- chloroquine diphosphate, (-)-isomer
- chloroquine phosphate
- delagil
- khingamin phosphate
- N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine, phosphate (1:2)
- Resochin
- unspecified phosphate of chloroquine diphosphate
- Chloroquine diphosphate
- Chloroquine phosphate
- 50-63-5
- Resochin
- Arechin
- Chloroquine diphosphate salt
- Avloclor
- Tanakan
- Aralen phosphate
- Quingamine
- Delagil
- Miniquine
- Tanakene
- Chloroquine bis(phosphate)
- Chlorochin diphosphate
- Chloroquine (phosphate)
- Chingamin phosphate
- dl-Chloroquine diphosphate
- Khingamin
- Ipsen 225
- NSC 14050
- Aralen diphosphate
- CCRIS 1554
- Unikinon
- Gontochin phosphate
- Chloroquin diphosphate
- EINECS 200-055-2
- MFCD00069852
- N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine bis(phosphate)
- Chloroquine dihydrogen phosphate (1:2)
- UNII-6E17K3343P
- AI3-14952
- NSC-14050
- 6E17K3343P
- SN-7618
- WR-1522
- N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt
- DTXSID7044681
- Chloroquine phosphate [USP:BAN]
- 3377 RP
- Chloroquine (phosphate) (Standard)
- 50-63-5 (DIPHOSPHATE)
- SN 7,618
- 7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline phosphate (1:2)
- 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, phosphate (1:2)
- N(4)-(7-Chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine, phosphate (1:2)
- 1,4-Pentanediamine, N(sup 4)-(7-chloro-4-quinolinyl)-N(sup 1),N(sup 1)-diethyl-, phosphate (1:2)
- Chingaminum
- Alermine
- H-Stadur
- 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N',N'-diethyl-, (+-)-, phosphate (1:2)
- Quinoline, 7-chloro-4-((4-(diethylamino)-1-methylbutyl)amino)-, phosphate (1:2)
- DTXCID5024681
- Chloroquine phosphate (USP:BAN)
- Tanakan (antimalarial)
- CHLOROQUINE PHOSPHATE (MART.)
- CHLOROQUINE PHOSPHATE [MART.]
- CHLOROQUINE PHOSPHATE (USP-RS)
- CHLOROQUINE PHOSPHATE [USP-RS]
- 7-CHLORO-4-((4-(DIETHYLAMINO)-1-METHYLBUTYL)AMINO)QUINOLINE PHOSPHATE (1:2).
- CHLOROQUINE PHOSPHATE (EP MONOGRAPH)
- CHLOROQUINE PHOSPHATE [EP MONOGRAPH]
- Chloroquinediphosphate
- NSC14050
- CHLOROQUINE PHOSPHATE (USP MONOGRAPH)
- CHLOROQUINE PHOSPHATE [USP MONOGRAPH]
- SR-01000075548
- WR 1522
- Chloroquindiphosphat
- Chloroquinum Phos.
- Chloroquini phosphas
- Prestwick_867
- Aralen (TN)
- CAS-50-63-5
- NCGC00015256-01
- 7-Chlor-4-(4-(diaethylamino)-1-methylbutylamino)-chinolindiphosphat [German]
- Chloroquine diphosphate,(S)
- 1,4-diamine bis(phosphate)
- Chloroquine phosphate (USP)
- SCHEMBL40827
- CHEMBL58510
- SPECTRUM1500179
- C18H26ClN3?2H3PO4
- HMS501E06
- QKICWELGRMTQCR-UHFFFAOYSA-N
- HMS1569N17
- HMS1920O05
- HMS2091C16
- HMS2096N17
- HMS3260L14
- HMS3713N17
- BCP31956
- CHLOROQUINE DIPHOSPHATE [MI]
- Tox21_110115
- Tox21_202838
- Tox21_500296
- 7-Chlor-4-(4-(diaethylamino)-1-methylbutylamino)-chinolindiphosphat
- CCG-39643
- CHLOROQUINE PHOSPHATE [VANDF]
- HB5073
- HY-17589R
- s4157
- AKOS004910410
- CHLOROQUINE PHOSPHATE [WHO-DD]
- CHLOROQUINE PHOSPHATE [WHO-IP]
- N4-(7-chloro-4-quinolyl)-N1,N1-diethyl-pentane-1,4-diamine; phosphoric acid
- Quinoline, 7-chloro-4-(4-diethylamino-1-methyl-butylamino)-, diphosphate
- Tox21_110115_1
- CS-3811
- DT-0015
- LP00296
- NCGC00015256-12
- NCGC00093746-01
- NCGC00093746-02
- NCGC00093746-03
- NCGC00260384-01
- NCGC00260981-01
- AC-12463
- CHLOROQUINE PHOSPHATE [GREEN BOOK]
- HY-17589
- SY021941
- CHLOROQUINE PHOSPHATE [ORANGE BOOK]
- CHLOROQUINI PHOSPHAS [WHO-IP LATIN]
- DB-051808
- C2301
- Chloroquine diphosphate salt, solid, >=98%
- CS-0695021
- EU-0100296
- NS00078674
- C 6628
- D02125
- D70732
- EN300-100253
- N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-
- SR-01000075548-1
- SR-01000075548-3
- SR-01000075548-5
- Q27264629
- F2173-1139
- Z1541662176
- 7-Chloro-4-[4-(diethylamino)-1-methylbutylamino]quinoline Bis(phosphate)
- 7-Chloro-4-[4-(diethylamino)-1-methylbutylamino]quinoline Diphosphate
- Chloroquine phosphate, United States Pharmacopeia (USP) Reference Standard
- N4-(7-Chloro-4-quinolyl)-N1,N1-diethyl-1,4-pentanediamine Diphosphate
- 7-CHLORO-N-[5-(DIETHYLAMINO)PENTAN-2-YL]QUINOLIN-4-AMINE; BIS(PHOSPHORIC ACID)
- Chloroquine phosphate, Pharmaceutical Secondary Standard; Certified Reference Material
- Chloroquine phosphate;Aralen phosphate;7-chloro-4-((4 inverted exclamation mark -diethylamino-1-methylbutyl)amino)quinolinediphosphate
- Chloroquine (has active moiety)
- Chloroquine phosphate; primaquine phosphate (component of)
- Chloroquine Phosphate; Embutramide; Lidocaine (component of)
Information on 1 consumer products that contain Chloroquine phosphate in the following categories is provided:
• Pet Care
H302 (98.7%): Harmful if swallowed [Warning Acute toxicity, oral]
H360 (32.5%): May damage fertility or the unborn child [Danger Reproductive toxicity]
H373 (32.5%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
P203, P260, P264, P270, P280, P301+P317, P318, P319, P330, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)
Aggregated GHS information provided per 77 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.
Acute Tox. 4 (98.7%)
Repr. 1A (32.5%)
STOT RE 2 (32.5%)
IMAP assessments - 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, phosphate (1:2): Environment tier I assessment
IMAP assessments - 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, phosphate (1:2): Human health tier I assessment
◉ Summary of Use during Lactation
Very small amounts of chloroquine are excreted in breast milk; when given once weekly, the amount of drug is not sufficient to harm the infant nor is the quantity sufficient to protect the child from malaria. United Kingdom malaria treatment guidelines recommend that weekly chloroquine 500 mg be given until breastfeeding is completed and primaquine can be given. Breastfeeding infants should receive the recommended dosages of chloroquine for malaria prophylaxis.In HIV-infected women, elevated viral HIV loads in milk were decreased after treatment with chloroquine to a greater extent than other women who were treated with the combination of sulfadoxine and pyrimethamine. Because no information is available on the daily use of chloroquine during breastfeeding, hydroxychloroquine or another agent may be preferred in this situation, especially while nursing a newborn or preterm infant.
◉ Effects in Breastfed Infants
Several authors have pointed out that malaria prophylaxis in nursing mothers with chloroquine is common in endemic areas. As of the revision date, no reports of adverse reactions in breastfed infants have been published.
◉ Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=QKICWELGRMTQCR-UHFFFAOYSA-N
- Australian Industrial Chemicals Introduction Scheme (AICIS)1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, phosphate (1:2)https://services.industrialchemicals.gov.au/search-assessments/
- ChemIDplusChloroquine phosphate [USP:BAN]https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0000050635ChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
- EPA DSSToxChloroquine bis(phosphate)https://comptox.epa.gov/dashboard/DTXSID7044681CompTox Chemicals Dashboard Chemical Listshttps://comptox.epa.gov/dashboard/chemical-lists/
- European Chemicals Agency (ECHA)LICENSEUse of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.https://echa.europa.eu/web/guest/legal-noticeChloroquine bis(phosphate)https://echa.europa.eu/substance-information/-/substanceinfo/100.000.051Chloroquine bis(phosphate) (EC: 200-055-2)https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/75212
- FDA Global Substance Registration System (GSRS)LICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linkingCHLOROQUINE PHOSPHATEhttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/6E17K3343P
- CCSbaseCCSbase Classificationhttps://ccsbase.net/
- ChEMBLLICENSEAccess to the web interface of ChEMBL is made under the EBI's Terms of Use (http://www.ebi.ac.uk/Information/termsofuse.html). The ChEMBL data is made available on a Creative Commons Attribution-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-sa/3.0/).http://www.ebi.ac.uk/Information/termsofuse.htmlChEMBL Protein Target Treehttps://www.ebi.ac.uk/chembl/g/#browse/targets
- ClinicalTrials.govLICENSEThe ClinicalTrials.gov data carry an international copyright outside the United States and its Territories or Possessions. Some ClinicalTrials.gov data may be subject to the copyright of third parties; you should consult these entities for any additional terms of use.https://clinicaltrials.gov/ct2/about-site/terms-conditions#Use
- Comparative Toxicogenomics Database (CTD)LICENSEIt is to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of NC State University.http://ctdbase.org/about/legal.jspchloroquine diphosphatehttps://ctdbase.org/detail.go?type=chem&acc=C023676Ginkgo biloba extracthttps://ctdbase.org/detail.go?type=chem&acc=C063170
- Open TargetsLICENSEDatasets generated by the Open Targets Platform are freely available for download.https://platform-docs.opentargets.org/licenceCHLOROQUINE PHOSPHATEhttps://platform.opentargets.org/drug/CHEMBL58510
- Consumer Product Information Database (CPID)LICENSECopyright (c) 2024 DeLima Associates. All rights reserved. Unless otherwise indicated, all materials from CPID are copyrighted by DeLima Associates. No part of these materials, either text or image may be used for any purpose other than for personal use. Therefore, reproduction, modification, storage in a retrieval system or retransmission, in any form or by any means, electronic, mechanical or otherwise, for reasons other than personal use, is strictly prohibited without prior written permission.https://www.whatsinproducts.com/contents/view/1/6Chloroquine phosphatehttps://www.whatsinproducts.com/chemicals/view/1/6339/000050-63-5Consumer Products Category Classificationhttps://www.whatsinproducts.com/
- DailyMedCHLOROQUINE PHOSPHATEhttps://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=CHLOROQUINE+PHOSPHATECHLOROQUINE DIPHOSPHATEhttps://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=CHLOROQUINE+DIPHOSPHATE
- Drugs and Lactation Database (LactMed)
- Drugs@FDALICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linkingCHLOROQUINE PHOSPHATEhttps://www.accessdata.fda.gov/scripts/cder/daf/
- EU Clinical Trials Register
- FDA Approved Animal Drug Products (Green Book)LICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linking
- FDA Orange BookLICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linking
- KEGGLICENSEAcademic users may freely use the KEGG website. Non-academic use of KEGG generally requires a commercial licensehttps://www.kegg.jp/kegg/legal.htmlUSP drug classificationhttp://www.genome.jp/kegg-bin/get_htext?br08302.kegAnatomical Therapeutic Chemical (ATC) classificationhttp://www.genome.jp/kegg-bin/get_htext?br08303.kegAntiinfectiveshttp://www.genome.jp/kegg-bin/get_htext?br08307.keg
- National Drug Code (NDC) DirectoryLICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linkingCHLOROQUINE PHOSPHATEhttps://www.fda.gov/drugs/drug-approvals-and-databases/national-drug-code-directory
- Natural Product Activity and Species Source (NPASS)
- NCI Thesaurus (NCIt)LICENSEUnless otherwise indicated, all text within NCI products is free of copyright and may be reused without our permission. Credit the National Cancer Institute as the source.https://www.cancer.gov/policies/copyright-reuseNCI Thesaurushttps://ncit.nci.nih.gov
- NLM RxNorm TerminologyLICENSEThe RxNorm Terminology is created by the National Library of Medicine (NLM) and is in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from NLM. Credit to the U.S. National Library of Medicine as the source is appreciated but not required. The full RxNorm dataset requires a free license.https://www.nlm.nih.gov/research/umls/rxnorm/docs/termsofservice.htmlchloroquine phosphatehttps://rxnav.nlm.nih.gov/id/rxnorm/20863
- SpectraBaseChloroquine Phosphatehttps://spectrabase.com/spectrum/EJmaD6YsP2XChloroquine diphosphate salthttps://spectrabase.com/spectrum/84254Z22qLpChloroquine phosphatehttps://spectrabase.com/spectrum/LReEHHjmHR6
- Springer Nature
- Wikidatachloroquine phosphatehttps://www.wikidata.org/wiki/Q27264629
- PubChem
- Medical Subject Headings (MeSH)LICENSEWorks produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.https://www.nlm.nih.gov/copyright.htmlchloroquine diphosphatehttps://www.ncbi.nlm.nih.gov/mesh/67023676Anti-Inflammatory Agents, Non-Steroidalhttps://www.ncbi.nlm.nih.gov/mesh/68000894Antimalarialshttps://www.ncbi.nlm.nih.gov/mesh/68000962Filaricideshttps://www.ncbi.nlm.nih.gov/mesh/68005369
- GHS Classification (UNECE)GHS Classification Treehttp://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html
- NORMAN Suspect List ExchangeLICENSEData: CC-BY 4.0; Code (hosted by ECI, LCSB): Artistic-2.0https://creativecommons.org/licenses/by/4.0/NORMAN Suspect List Exchange Classificationhttps://www.norman-network.com/nds/SLE/
- EPA Substance Registry ServicesEPA SRS List Classificationhttps://sor.epa.gov/sor_internet/registry/substreg/LandingPage.do
- MolGenieMolGenie Organic Chemistry Ontologyhttps://github.com/MolGenie/ontology/
- PATENTSCOPE (WIPO)SID 388556100https://pubchem.ncbi.nlm.nih.gov/substance/388556100
- NCBI