Emideltide;Delta Sleep Inducing Peptide
PubChem CID
3623358
Structure
Molecular Formula
Synonyms
- DSIP
- Emideltide;Delta Sleep Inducing Peptide
- SCHEMBL5523007
- DTXSID50866936
- AS-83056
Molecular Weight
848.8 g/mol
Computed by PubChem 2.1 (PubChem release 2021.05.07)
Dates
- Create:2005-09-09
- Modify:2025-01-18
Description
A nonapeptide that is found in neurons, peripheral organs, and plasma. This neuropeptide induces mainly delta sleep in mammals. In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal.
Chemical Structure Depiction
Conformer generation is disallowed since too many atoms, too flexible, too many undefined stereo centers
SVG Image
IUPAC Condensed
H-DL-Trp-DL-Ala-Gly-Gly-DL-Asp-DL-Ala-DL-Ser-Gly-DL-Glu-OH
Sequence
WAGGDASGE
PLN
H-WAGGDASGE-OH
HELM
PEPTIDE1{(W,[dW]).(A,[dA]).G.G.(D,[dD]).(A,[dA]).(S,[dS]).G.(E,[dE])}$$$$V2.0
IUPAC
DL-tryptophyl-DL-alanyl-glycyl-glycyl-DL-alpha-aspartyl-DL-alanyl-DL-seryl-glycyl-DL-glutamic acid
2-[[2-[[2-[2-[[2-[[2-[[2-[2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoylamino]acetyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]propanoylamino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanedioic acid
Computed by Lexichem TK 2.7.0 (PubChem release 2021.05.07)
InChI=1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)
Computed by InChI 1.0.6 (PubChem release 2021.05.07)
ZRZROXNBKJAOKB-UHFFFAOYSA-N
Computed by InChI 1.0.6 (PubChem release 2021.05.07)
CC(C(=O)NCC(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CO)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)N
Computed by OEChem 2.3.0 (PubChem release 2024.12.12)
C35H48N10O15
Computed by PubChem 2.1 (PubChem release 2021.05.07)
- Delta Sleep Inducing Peptide
- Delta Sleep Peptide
- Delta Sleep-Inducing Peptide
- Delta-Sleep Peptide
- Delta-Sleep-Inducing Peptide
- Delta-Sleep-Inducing-Peptide
- DSIP
- Peptide, Delta Sleep-Inducing
- Peptide, Delta-Sleep
- Peptide, Delta-Sleep-Inducing
- Sleep-Inducing Peptide, Delta
- Trp Ala Gly Gly Asp Ala Ser Gly Glu
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
- DSIP
- Emideltide;Delta Sleep Inducing Peptide
- SCHEMBL5523007
- DTXSID50866936
- AS-83056
- G77864
- Tryptophylalanylglycylglycyl-alpha-aspartylalanylserylglycylglutamic acid
- 2-[[2-[[2-[2-[[2-[[2-[[2-[2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoylamino]acetyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]propanoylamino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanedioic acid
Property Name
Property Value
Reference
Property Name
Molecular Weight
Property Value
848.8 g/mol
Reference
Computed by PubChem 2.1 (PubChem release 2021.05.07)
Property Name
XLogP3
Property Value
-7.1
Reference
Computed by XLogP3 3.0 (PubChem release 2021.05.07)
Property Name
Hydrogen Bond Donor Count
Property Value
14
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.05.07)
Property Name
Hydrogen Bond Acceptor Count
Property Value
16
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.05.07)
Property Name
Rotatable Bond Count
Property Value
25
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.05.07)
Property Name
Exact Mass
Property Value
848.33006086 Da
Reference
Computed by PubChem 2.1 (PubChem release 2021.05.07)
Property Name
Monoisotopic Mass
Property Value
848.33006086 Da
Reference
Computed by PubChem 2.1 (PubChem release 2021.05.07)
Property Name
Topological Polar Surface Area
Property Value
407 Ų
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.05.07)
Property Name
Heavy Atom Count
Property Value
60
Reference
Computed by PubChem
Property Name
Formal Charge
Property Value
0
Reference
Computed by PubChem
Property Name
Complexity
Property Value
1610
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.05.07)
Property Name
Isotope Atom Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Atom Stereocenter Count
Property Value
6
Reference
Computed by PubChem
Property Name
Defined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Covalently-Bonded Unit Count
Property Value
1
Reference
Computed by PubChem
Property Name
Compound Is Canonicalized
Property Value
Yes
Reference
Computed by PubChem (release 2019.01.04)
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Same Connectivity Count
Same Isotope Count
Same Parent, Connectivity Count
Same Parent, Isotope Count
Similar Compounds (2D)
Similar Conformers (3D)
Same Count
Neurotransmitter Agents
Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. (See all compounds classified as Neurotransmitter Agents.)
- EPA DSSToxTryptophylalanylglycylglycyl-alpha-aspartylalanylserylglycylglutamic acidhttps://comptox.epa.gov/dashboard/DTXSID50866936
- Human Metabolome Database (HMDB)LICENSEHMDB is offered to the public as a freely available resource. Use and re-distribution of the data, in whole or in part, for commercial purposes requires explicit permission of the authors and explicit acknowledgment of the source material (HMDB) and the original publication (see the HMDB citing page). We ask that users who download significant portions of the database cite the HMDB paper in any resulting publications.http://www.hmdb.ca/citing
- Medical Subject Headings (MeSH)LICENSEWorks produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.https://www.nlm.nih.gov/copyright.htmlDelta Sleep-Inducing Peptidehttps://www.ncbi.nlm.nih.gov/mesh/68003701Neurotransmitter Agentshttps://www.ncbi.nlm.nih.gov/mesh/68018377
- PubChem
CONTENTS