Toremifene Citrate
- TOREMIFENE CITRATE
- 89778-27-8
- Fareston
- FC 1157a
- Toremifene citrate [USAN]
- Create:2005-03-26
- Modify:2025-01-18
- Citrate, Toremifene
- Fareston
- FC 1157a
- FC-1157a
- FC1157a
- Toremifene
- Toremifene Citrate
- Toremifene Citrate (1:1)
- Toremifene, (E)-Isomer
- TOREMIFENE CITRATE
- 89778-27-8
- Fareston
- FC 1157a
- Toremifene citrate [USAN]
- Toremifene (Citrate)
- NK 622
- CCRIS 6719
- NSC 613680
- FC-1157a
- NSC-613680
- DTXSID2021367
- UNII-2498Y783QT
- 89778-27-8 (citrate)
- NSC613680
- 2498Y783QT
- DTXCID301367
- Citrate, Toremifene
- (Z)-4-Chloro-1,2-diphenyl-1-(4-(2-(N,N-dimethylamino)ethoxy)phenyl)-1-butene citrate (1:1)
- 2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine citrate (1:1)
- Ethanamine, 2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
- (2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine; 2-hydroxypropane-1,2,3-tricarboxylic acid
- (Z)-2-(4-(4-chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethan-1-amine 2-hydroxypropane-1,2,3-tricarboxylate
- TOREMIFENE CITRATE (MART.)
- TOREMIFENE CITRATE [MART.]
- 2-[p-[(Z)-4-Chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethylamine citrate (1:1)
- 2-({4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenyl}oxy)-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt)
- 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid
- CAS-89778-27-8
- Toremifene Citrate (1:1)
- MFCD01729016
- CPD000469213
- SCHEMBL4564
- MLS001306432
- MLS006011608
- CHEBI:9636
- TOREMIFENE CITRATE [MI]
- CHEMBL1200675
- Toremifene citrate (JAN/USAN)
- TOREMIFENE CITRATE [JAN]
- HY-B0005R
- Toremifene (citrate) (Standard)
- HMS2052C03
- HMS2230P09
- HMS3264L11
- Pharmakon1600-01505682
- TOREMIFENE CITRATE [VANDF]
- HY-B0005
- TOREMIFENE CITRATE [WHO-DD]
- Tox21_111877
- Tox21_301740
- NSC759190
- s1776
- AKOS015888270
- AC-1985
- CCG-101072
- CS-1272
- KS-5242
- NC00322
- NSC-759190
- 2-[4-[(Z)-4-chloro-1,2-diphenyl-but-1-enyl]phenoxy]-N,N-dimethyl-ethanamine; citric acid
- TOREMIFENE CITRATE [ORANGE BOOK]
- NCGC00255310-01
- Toremifene Citrate (Fareston, Acapodene)
- 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine; 2-hydroxypropane-1,2,3-tricarboxylic acid
- SMR004703372
- Toremifene citrate salt, >=98% (HPLC)
- "Toremifene Citrate (Fareston, Acapodene)"
- SW197702-3
- T2832
- D00967
- A843307
- SR-01000763502-3
- Q27253831
- 2-[p-[(Z)-4-chloro-1,N- dimethylethylamine citrate (1:1)
- (Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine Citrate
- (Z)-2-[4-(4-chloro-1,N- dimethylethanamine, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
- (Z)-4-Chloro-1-(4-dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene Citrate
- 2-(4-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine monocitrate
- 2-(p-((Z)-4-chloro-1,2-diphenyl-1-butenyl)-phenoxy)-N,N-dimethylethylamine citrate (1:1)
- (Z)-2-(4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine 2-Hydroxy-1,2,3-propanetricarboxylate (1:1)
- (Z)-2-(4-(4-chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate
- (Z)-2-(4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate
- 2-[4-[(Z)-4-chloranyl-1,2-diphenyl-but-1-enyl]phenoxy]-N,N-dimethyl-ethanamine; 2-oxidanylpropane-1,2,3-tricarboxylic acid
406.194641 100
408.191315 31.78
407.196716 29.54
409.193878 6.30
205.099274 1.32
Acapodene
Fareston
Toremifene citrate is approved to treat:
• Breast cancer that has spread to other parts of the body. It is used in postmenopausal women whose cancer is estrogen receptor positive (ER+) or when it is not known if the cancer is ER+ or estrogen receptor negative (ER-).
H302 (97.6%): Harmful if swallowed [Warning Acute toxicity, oral]
H318 (92.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
H400 (92.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
H410 (92.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
P264, P264+P265, P270, P273, P280, P301+P317, P305+P354+P338, P317, P330, P391, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)
Aggregated GHS information provided per 41 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.
Acute Tox. 4 (97.6%)
Eye Dam. 1 (92.7%)
Aquatic Acute 1 (92.7%)
Aquatic Chronic 1 (92.7%)
- Burnham Center for Chemical Genomics
- CAS Common ChemistryLICENSEThe data from CAS Common Chemistry is provided under a CC-BY-NC 4.0 license, unless otherwise stated.https://creativecommons.org/licenses/by-nc/4.0/Toremifene citratehttps://commonchemistry.cas.org/detail?cas_rn=89778-27-8
- ChemIDplusToremifene citrate [USAN]https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0089778278ChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
- DTP/NCILICENSEUnless otherwise indicated, all text within NCI products is free of copyright and may be reused without our permission. Credit the National Cancer Institute as the source.https://www.cancer.gov/policies/copyright-reuse
- EPA DSSToxToremifene citratehttps://comptox.epa.gov/dashboard/DTXSID2021367CompTox Chemicals Dashboard Chemical Listshttps://comptox.epa.gov/dashboard/chemical-lists/
- European Chemicals Agency (ECHA)LICENSEUse of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.https://echa.europa.eu/web/guest/legal-notice(Z)-1,2-diphenyl-1-[4-[2-(dimethylamino)etoxy]phenyl]-4-chloro-1-butencitratehttps://echa.europa.eu/substance-information/-/substanceinfo/100.189.661(Z)-1,2-diphenyl-1-[4-[2-(dimethylamino)etoxy]phenyl]-4-chloro-1-butencitrate (EC: 663-344-6)https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/194584
- FDA Global Substance Registration System (GSRS)LICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linkingTOREMIFENE CITRATEhttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/2498Y783QT
- CCSbaseCCSbase Classificationhttps://ccsbase.net/
- ChEBIToremifene citratehttps://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:9636
- NCI Thesaurus (NCIt)LICENSEUnless otherwise indicated, all text within NCI products is free of copyright and may be reused without our permission. Credit the National Cancer Institute as the source.https://www.cancer.gov/policies/copyright-reuseNCI Thesaurushttps://ncit.nci.nih.gov
- Open TargetsLICENSEDatasets generated by the Open Targets Platform are freely available for download.https://platform-docs.opentargets.org/licenceTOREMIFENE CITRATEhttps://platform.opentargets.org/drug/CHEMBL1200675
- ChEMBLLICENSEAccess to the web interface of ChEMBL is made under the EBI's Terms of Use (http://www.ebi.ac.uk/Information/termsofuse.html). The ChEMBL data is made available on a Creative Commons Attribution-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-sa/3.0/).http://www.ebi.ac.uk/Information/termsofuse.htmlChEMBL Protein Target Treehttps://www.ebi.ac.uk/chembl/g/#browse/targets
- ClinicalTrials.govLICENSEThe ClinicalTrials.gov data carry an international copyright outside the United States and its Territories or Possessions. Some ClinicalTrials.gov data may be subject to the copyright of third parties; you should consult these entities for any additional terms of use.https://clinicaltrials.gov/ct2/about-site/terms-conditions#Use
- Comparative Toxicogenomics Database (CTD)LICENSEIt is to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of NC State University.http://ctdbase.org/about/legal.jsp
- DailyMed
- Drugs@FDALICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linkingTOREMIFENE CITRATEhttps://www.accessdata.fda.gov/scripts/cder/daf/
- European Medicines Agency (EMA)LICENSEInformation on the European Medicines Agency's (EMA) website is subject to a disclaimer and copyright and limited reproduction notices.https://www.ema.europa.eu/en/about-us/legal-noticeFareston (EMEA/H/C/000091)https://www.ema.europa.eu/en/medicines/human/EPAR/fareston
- EU Clinical Trials Register
- FDA Orange BookLICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linking
- KEGGLICENSEAcademic users may freely use the KEGG website. Non-academic use of KEGG generally requires a commercial licensehttps://www.kegg.jp/kegg/legal.htmlTherapeutic category of drugs in Japanhttp://www.genome.jp/kegg-bin/get_htext?br08301.kegUSP drug classificationhttp://www.genome.jp/kegg-bin/get_htext?br08302.kegAnatomical Therapeutic Chemical (ATC) classificationhttp://www.genome.jp/kegg-bin/get_htext?br08303.kegTarget-based classification of drugshttp://www.genome.jp/kegg-bin/get_htext?br08310.keg
- MassBank of North America (MoNA)LICENSEThe content of the MoNA database is licensed under CC BY 4.0.https://mona.fiehnlab.ucdavis.edu/documentation/license"Toremifene Citrate (Fareston, Acapodene)"https://mona.fiehnlab.ucdavis.edu/spectra/browse?query=exists(compound.metaData.name:%27InChIKey%27%20and%20compound.metaData.value:%27IWEQQRMGNVVKQW-OQKDUQJOSA-N%27)
- National Drug Code (NDC) DirectoryLICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linking
- NCI Cancer DrugsFareston (Toremifene)https://www.cancer.gov/about-cancer/treatment/drugs/toremifene
- NLM RxNorm TerminologyLICENSEThe RxNorm Terminology is created by the National Library of Medicine (NLM) and is in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from NLM. Credit to the U.S. National Library of Medicine as the source is appreciated but not required. The full RxNorm dataset requires a free license.https://www.nlm.nih.gov/research/umls/rxnorm/docs/termsofservice.htmltoremifene citratehttps://rxnav.nlm.nih.gov/id/rxnorm/49953
- Wikidatatoremifene citratehttps://www.wikidata.org/wiki/Q27253831
- Medical Subject Headings (MeSH)LICENSEWorks produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.https://www.nlm.nih.gov/copyright.htmlAntineoplastic Agents, Hormonalhttps://www.ncbi.nlm.nih.gov/mesh/68018931Bone Density Conservation Agentshttps://www.ncbi.nlm.nih.gov/mesh/68050071Selective Estrogen Receptor Modulatorshttps://www.ncbi.nlm.nih.gov/mesh/68020845
- PubChem
- GHS Classification (UNECE)GHS Classification Treehttp://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html
- MolGenieMolGenie Organic Chemistry Ontologyhttps://github.com/MolGenie/ontology/
- NCBI