An official website of the United States government

Sodium Lauroyl Sarcosinate

PubChem CID
23668817
Structure
Sodium Lauroyl Sarcosinate_small.png
Sodium Lauroyl Sarcosinate_3D_Structure.png
Molecular Formula
Synonyms
  • 137-16-6
  • N-Lauroylsarcosine sodium salt
  • Sodium lauroylsarcosinate
  • Sodium N-lauroylsarcosinate
  • Sarkosyl NL
Molecular Weight
293.38 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Dates
  • Create:
    2008-02-05
  • Modify:
    2025-01-18
Description
Sodium lauroyl sarcosinate is an sodium salt of an acyl derivative of sarcosine, which is a natural amino acid found in muscles and other body tissues. Acyl sarcosines are considered modifiŽed fatty acids in which the hydrocarbon chains are interrupted by an amidomethyl group in the alpha position. They are used as hair-conditioning agents and surfactant-cleansing agents in cosmetics, as well as to improve wetting and penetration of topical pharmaceutical products. Acyl sarcosines and their sodium salts are also used in the metal finishing and processing industries for their crystal modifying, anti-rust, and anti-corrosion properties. (L1892, A2881)
A2881: Lanigan RS: Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate. Int J Toxicol. 2001;20 Suppl 1:1-14. PMID:11358107
L1892: Wikipedia. Sarcosine. Last Updated 16 October 2009. http://en.wikipedia.org/wiki/Sarcosine

1 Structures

1.1 2D Structure

Chemical Structure Depiction
Sodium Lauroyl Sarcosinate.png

1.2 3D Conformer

3D Conformer of Parent

2 Biologic Description

SVG Image
SVG Image
IUPAC Condensed
lauroyl-Sar-OH.Na+
Sequence
G
IUPAC
N-lauroyl-sarcosine sodium salt

3 Names and Identifiers

3.1 Computed Descriptors

3.1.1 IUPAC Name

sodium;2-[dodecanoyl(methyl)amino]acetate
Computed by Lexichem TK 2.7.0 (PubChem release 2021.10.14)

3.1.2 InChI

InChI=1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1
Computed by InChI 1.0.6 (PubChem release 2021.10.14)

3.1.3 InChIKey

KSAVQLQVUXSOCR-UHFFFAOYSA-M
Computed by InChI 1.0.6 (PubChem release 2021.10.14)

3.1.4 SMILES

CCCCCCCCCCCC(=O)N(C)CC(=O)[O-].[Na+]
Computed by OEChem 2.3.0 (PubChem release 2024.12.12)

3.2 Molecular Formula

C15H28NNaO3
Computed by PubChem 2.2 (PubChem release 2021.10.14)

3.3 Other Identifiers

3.3.1 CAS

137-16-6

3.3.2 Deprecated CAS

1322-85-6, 75195-12-9, 76724-33-9, 912455-41-5
1322-85-6, 76724-33-9, 912455-41-5

3.3.3 European Community (EC) Number

3.3.4 UNII

3.3.5 ChEMBL ID

3.3.6 DSSTox Substance ID

3.3.7 Nikkaji Number

3.3.8 RXCUI

3.3.9 Wikidata

3.3.10 Wikipedia

3.4 Synonyms

3.4.1 MeSH Entry Terms

  • Gardol
  • lauroyl sarcosine
  • N-dodecanoyl-N-methylglycine
  • N-lauroyl sarcosinate
  • N-lauroyl sarcosine
  • N-lauroyl-N-methylaminoacetic acid
  • N-lauroylsarcosinate
  • N-lauroylsarcosine
  • N-lauroylsarcosine sodium salt
  • N-methyl-N-(1-oxododecyl)glycine sodium salt (1:1)
  • sarcosyl NL
  • sarkosyl
  • sarkosyl L
  • sarkosyl NL
  • sarkosyl NL 30
  • sarkosyl, ammonium salt
  • sarkosyl, potassium salt
  • sodium lauroyl sarcosinate
  • sodium N-lauroyl sarcosinate
  • sodium N-lauroylsarcosinate
  • sodium N-laurylsarcosinate

3.4.2 Depositor-Supplied Synonyms

4 Chemical and Physical Properties

4.1 Computed Properties

Property Name
Molecular Weight
Property Value
293.38 g/mol
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Hydrogen Bond Donor Count
Property Value
0
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Hydrogen Bond Acceptor Count
Property Value
3
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Rotatable Bond Count
Property Value
12
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Exact Mass
Property Value
293.19668804 Da
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Monoisotopic Mass
Property Value
293.19668804 Da
Reference
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Property Name
Topological Polar Surface Area
Property Value
60.4 Ų
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Heavy Atom Count
Property Value
20
Reference
Computed by PubChem
Property Name
Formal Charge
Property Value
0
Reference
Computed by PubChem
Property Name
Complexity
Property Value
260
Reference
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Property Name
Isotope Atom Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Atom Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Defined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Undefined Bond Stereocenter Count
Property Value
0
Reference
Computed by PubChem
Property Name
Covalently-Bonded Unit Count
Property Value
2
Reference
Computed by PubChem
Property Name
Compound Is Canonicalized
Property Value
Yes
Reference
Computed by PubChem (release 2021.10.14)

4.2 Experimental Properties

4.2.1 Physical Description

Dry Powder, Liquid; Liquid
White powder; [Sigma-Aldrich MSDS]

4.2.2 Vapor Pressure

0.02 [mmHg]

4.3 Chemical Classes

Other Uses -> Emulsifiers/Surfactants

4.3.1 Cosmetics

Cosmetic ingredients (Sodium Lauroyl Sarcosinate) -> CIR (Cosmetic Ingredient Review)
Surfactant; Antistatic; Hair conditioning; Cleansing; Viscosity controlling; Emulsifying; Skin conditioning; Foaming
S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118

5 Spectral Information

5.1 1D NMR Spectra

5.1.1 1H NMR Spectra

Instrument Name
Varian A-60
Copyright
Copyright © 2009-2024 John Wiley & Sons, Inc. All Rights Reserved.
Thumbnail
Thumbnail

5.2 IR Spectra

5.2.1 FTIR Spectra

1 of 2
Technique
FILM
Source of Sample
Alrose Chemical Company, Providence, Rhode Island
Copyright
Copyright © 1980, 1981-2024 John Wiley & Sons, Inc. All Rights Reserved.
Thumbnail
Thumbnail
2 of 2
Technique
Dried, KBr
Source of Sample
Hoechst AG, Frankfurt/Main, Germany
Copyright
Copyright © 1989, 1990-2024 Wiley-VCH Verlag GmbH & Co. KGaA. All Rights Reserved.
Thumbnail
Thumbnail

7 Chemical Vendors

8 Drug and Medication Information

8.1 Clinical Trials

8.1.1 EU Clinical Trials Register

9 Pharmacology and Biochemistry

9.1 MeSH Pharmacological Classification

Detergents
Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties. (See all compounds classified as Detergents.)

9.2 Metabolism / Metabolites

Acyl sarcosines can be absorbed following oral or dermal contact, while nitrosamines can enter the body via ingestion, inhalation, or dermal contact. Once in the body, nitrosamines are metabolized by cytochrome P-450 enzymes, which essentially activates them into carcinogens. Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase. (A2878, A2879, L1892)
A2878: Oyama T, Sugio K, Uramoto H, Iwata T, Onitsuka T, Isse T, Nozoe T, Kagawa N, Yasumoto K, Kawamoto T: Increased cytochrome P450 and aryl hydrocarbon receptor in bronchial epithelium of heavy smokers with non-small cell lung carcinoma carries a poor prognosis. Front Biosci. 2007 May 1;12:4497-503. PMID:17485391
A2879: Sasaki S, Sata F, Katoh S, Saijo Y, Nakajima S, Washino N, Konishi K, Ban S, Ishizuka M, Kishi R: Adverse birth outcomes associated with maternal smoking and polymorphisms in the N-Nitrosamine-metabolizing enzyme genes NQO1 and CYP2E1. Am J Epidemiol. 2008 Mar 15;167(6):719-26. doi: 10.1093/aje/kwm360. Epub 2008 Jan 23. PMID:18218609
L1892: Wikipedia. Sarcosine. Last Updated 16 October 2009. http://en.wikipedia.org/wiki/Sarcosine

10 Use and Manufacturing

10.1 Uses

Cosmetic Ingredient Review Link
EPA CPDat Chemical and Product Categories
The Chemical and Products Database, a resource for exposure-relevant data on chemicals in consumer products, Scientific Data, volume 5, Article number: 180125 (2018), DOI:10.1038/sdata.2018.125
Sources/Uses
Used as a detergent, foaming agent, and antienzyme for dentifrices; [Merck Index] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]
Merck Index - O'Neil MJ, Heckelman PE, Dobbelaar PH, Roman KJ (eds). The Merck Index, An Encyclopedia of Chemicals, Drugs, and Biologicals, 15th Ed. Cambridge, UK: The Royal Society of Chemistry, 2013.
Acyl sarcosines are used as hair-conditioning agents and surfactant-cleansing agents in cosmetics, as well as to improve wetting and penetration of topical pharmaceutical products. Acyl sarcosines and their sodium salts are also used in the metal finishing and processing industries for their crystal modifying, anti-rust, and anti-corrosion properties. (A2881)
A2881: Lanigan RS: Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate. Int J Toxicol. 2001;20 Suppl 1:1-14. PMID:11358107

10.1.1 Use Classification

EPA Safer Chemical Functional Use Classes -> Surfactants
Safer Chemical Classes -> Green circle Green circle - The chemical has been verified to be of low concern
Cosmetics -> Surfactant; Antistatic; Hair conditioning; Cleansing; Viscosity controlling; Emulsifying; Skin conditioning; Foaming
S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118

10.1.2 Industry Uses

  • Lubricating agent
  • Surfactant (surface active agent)
  • Surface active agents
  • Corrosion inhibitor
  • Lubricants and lubricant additives

10.1.3 Consumer Uses

  • Lubricating agent
  • Surfactant (surface active agent)
  • Surface active agents

10.1.4 Household Products

Household & Commercial/Institutional Products

Information on 186 consumer products that contain Sodium lauroyl sarcosinate in the following categories is provided:

• Auto Products

• Commercial / Institutional

• Inside the Home

• Landscaping/Yard

• Personal Care

10.2 U.S. Production

Aggregated Product Volume

2019: 1,000,000 - <10,000,000 lb

2018: 1,000,000 - <10,000,000 lb

2017: 1,000,000 - <10,000,000 lb

2016: 1,000,000 - <10,000,000 lb

10.3 General Manufacturing Information

Industry Processing Sectors
  • Soap, Cleaning Compound, and Toilet Preparation Manufacturing
  • Not Known or Reasonably Ascertainable
  • Petroleum Lubricating Oil and Grease Manufacturing
  • Miscellaneous Manufacturing
  • Wholesale and Retail Trade
EPA TSCA Commercial Activity Status
Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1): ACTIVE

11 Safety and Hazards

11.1 Hazards Identification

11.1.1 GHS Classification

Note
Pictograms displayed are for 95.2% (669 of 703) of reports that indicate hazard statements. This chemical does not meet GHS hazard criteria for 4.8% (34 of 703) of reports.
Pictogram(s)
Corrosive
Acute Toxic
Irritant
Signal
Danger
GHS Hazard Statements

H315 (83.2%): Causes skin irritation [Warning Skin corrosion/irritation]

H318 (81.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

H319 (13.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H330 (81.4%): Fatal if inhaled [Danger Acute toxicity, inhalation]

Precautionary Statement Codes

P260, P264, P264+P265, P271, P280, P284, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P320, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

(The corresponding statement to each P-code can be found at the GHS Classification page.)

ECHA C&L Notifications Summary

Aggregated GHS information provided per 703 reports by companies from 21 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 34 of 703 reports by companies. For more detailed information, please visit ECHA C&L website.

There are 20 notifications provided by 669 of 703 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

11.1.2 Hazard Classes and Categories

Skin Irrit. 2 (83.2%)

Eye Dam. 1 (81.7%)

Eye Irrit. 2 (13.4%)

Acute Tox. 2 (81.4%)

11.1.3 EPA Safer Chemical

Chemical: Gardol

Green circle Green circle - The chemical has been verified to be of low concern based on experimental and modeled data.

11.1.4 Hazards Summary

An irritant that may cause serious eye injury; Highly toxic by inhalation; Not a skin sensitizer in guinea pig maximization test; [Sigma-Aldrich MSDS]

11.2 Regulatory Information

The Australian Inventory of Industrial Chemicals
Chemical: Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt
REACH Registered Substance
New Zealand EPA Inventory of Chemical Status
Sodium lauroyl sarcosinate: Does not have an individual approval but may be used under an appropriate group standard

12 Toxicity

12.1 Toxicological Information

12.1.1 Toxicity Summary

While acyl sarcosines themselves are not toxic, they are nitrosating agents. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are produced from secondary amines and amides in the presence of nitrite ions and are believed to be carcinogenic. The particular nitrosamine produced by acyl sarcosines is N-nitrososarcosine. Once in the body, nitrosamines are activated by cytochrome P-450 enzymes. They are then believed to induce their carcinogenic effects by forming DNA adducts at the N- and O-atoms. (L1889, L1890, A2878, A2879, A2880, A2881)
A2878: Oyama T, Sugio K, Uramoto H, Iwata T, Onitsuka T, Isse T, Nozoe T, Kagawa N, Yasumoto K, Kawamoto T: Increased cytochrome P450 and aryl hydrocarbon receptor in bronchial epithelium of heavy smokers with non-small cell lung carcinoma carries a poor prognosis. Front Biosci. 2007 May 1;12:4497-503. PMID:17485391
A2879: Sasaki S, Sata F, Katoh S, Saijo Y, Nakajima S, Washino N, Konishi K, Ban S, Ishizuka M, Kishi R: Adverse birth outcomes associated with maternal smoking and polymorphisms in the N-Nitrosamine-metabolizing enzyme genes NQO1 and CYP2E1. Am J Epidemiol. 2008 Mar 15;167(6):719-26. doi: 10.1093/aje/kwm360. Epub 2008 Jan 23. PMID:18218609
A2880: Drablos F, Feyzi E, Aas PA, Vaagbo CB, Kavli B, Bratlie MS, Pena-Diaz J, Otterlei M, Slupphaug G, Krokan HE: Alkylation damage in DNA and RNA--repair mechanisms and medical significance. DNA Repair (Amst). 2004 Nov 2;3(11):1389-407. PMID:15380096
A2881: Lanigan RS: Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate. Int J Toxicol. 2001;20 Suppl 1:1-14. PMID:11358107
L1889: Wikipedia. Nitrosamine. Last Updated 16 November 2009. http://en.wikipedia.org/wiki/Nitrosamine
L1890: Organic Natural Health (1998). Cancer Causing Toxic Chemical Ingredients in Cosmetic and Skin Care Products. http://www.health-report.co.uk/ingredients-directory.htm

12.1.2 Carcinogen Classification

Carcinogen Classification
No indication of carcinogenicity (not listed by IARC). (L135)

12.1.3 Health Effects

Acyl sarcosines may cause irritation to the skin and eyes. They may also react to produce N-nitrososarcosine, which is believed to be carcinogenic. (A2881)
A2881: Lanigan RS: Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate. Int J Toxicol. 2001;20 Suppl 1:1-14. PMID:11358107

12.1.4 Exposure Routes

Oral (A2881) ; inhalation (A2881) ; dermal (A2881)
A2881: Lanigan RS: Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate. Int J Toxicol. 2001;20 Suppl 1:1-14. PMID:11358107

12.1.5 Symptoms

Acyl sarcosines may cause irritation to the skin and eyes. (A2881)
A2881: Lanigan RS: Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate. Int J Toxicol. 2001;20 Suppl 1:1-14. PMID:11358107

12.1.6 Toxicity Data

LC50 (rat) = 50-500 mg/m3/4hr
LD50: 175 mg/kg (Intravenous, Rat) (A2881) LD50: 2.1 g/kg (Oral, Mouse) (A2881)
A2881: Lanigan RS: Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate. Int J Toxicol. 2001;20 Suppl 1:1-14. PMID:11358107

13 Literature

13.1 Consolidated References

13.2 NLM Curated PubMed Citations

13.3 Springer Nature References

13.4 Chemical Co-Occurrences in Literature

13.5 Chemical-Gene Co-Occurrences in Literature

13.6 Chemical-Disease Co-Occurrences in Literature

14 Patents

14.1 Depositor-Supplied Patent Identifiers

14.2 WIPO PATENTSCOPE

14.3 Chemical Co-Occurrences in Patents

14.4 Chemical-Disease Co-Occurrences in Patents

14.5 Chemical-Gene Co-Occurrences in Patents

15 Interactions and Pathways

15.1 Chemical-Target Interactions

16 Biological Test Results

16.1 BioAssay Results

17 Classification

17.1 MeSH Tree

17.2 EPA Safer Choice

17.3 ChemIDplus

17.4 UN GHS Classification

17.5 EPA CPDat Classification

17.6 NORMAN Suspect List Exchange Classification

17.7 EPA DSSTox Classification

17.8 Consumer Product Information Database Classification

17.9 EPA TSCA and CDR Classification

17.10 EPA Substance Registry Services Tree

17.11 MolGenie Organic Chemistry Ontology

18 Information Sources

  1. Australian Industrial Chemicals Introduction Scheme (AICIS)
    Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt
    https://services.industrialchemicals.gov.au/search-inventory/
  2. ChemIDplus
    ChemIDplus Chemical Information Classification
    https://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
  3. EPA Chemical Data Reporting (CDR)
    LICENSE
    The U.S. Government retains a nonexclusive, royalty-free license to publish or reproduce these documents, or allow others to do so, for U.S. Government purposes. These documents may be freely distributed and used for non-commercial, scientific and educational purposes.
    https://www.epa.gov/web-policies-and-procedures/epa-disclaimers#copyright
    Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1)
    https://www.epa.gov/chemical-data-reporting
  4. EPA Chemicals under the TSCA
    Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1)
    https://www.epa.gov/chemicals-under-tsca
    EPA TSCA Classification
    https://www.epa.gov/tsca-inventory
  5. EPA DSSTox
    Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt
    https://comptox.epa.gov/dashboard/DTXSID0027066
    CompTox Chemicals Dashboard Chemical Lists
    https://comptox.epa.gov/dashboard/chemical-lists/
  6. European Chemicals Agency (ECHA)
    LICENSE
    Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.
    https://echa.europa.eu/web/guest/legal-notice
    Sodium N-lauroylsarcosinate
    https://chem.echa.europa.eu/100.004.801
  7. FDA Global Substance Registration System (GSRS)
    LICENSE
    Unless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.
    https://www.fda.gov/about-fda/about-website/website-policies#linking
  8. New Zealand Environmental Protection Authority (EPA)
    LICENSE
    This work is licensed under the Creative Commons Attribution-ShareAlike 4.0 International licence.
    https://www.epa.govt.nz/about-this-site/general-copyright-statement/
  9. ChEMBL
    LICENSE
    Access to the web interface of ChEMBL is made under the EBI's Terms of Use (http://www.ebi.ac.uk/Information/termsofuse.html). The ChEMBL data is made available on a Creative Commons Attribution-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-sa/3.0/).
    http://www.ebi.ac.uk/Information/termsofuse.html
  10. Consumer Product Information Database (CPID)
    LICENSE
    Copyright (c) 2024 DeLima Associates. All rights reserved. Unless otherwise indicated, all materials from CPID are copyrighted by DeLima Associates. No part of these materials, either text or image may be used for any purpose other than for personal use. Therefore, reproduction, modification, storage in a retrieval system or retransmission, in any form or by any means, electronic, mechanical or otherwise, for reasons other than personal use, is strictly prohibited without prior written permission.
    https://www.whatsinproducts.com/contents/view/1/6
    Consumer Products Category Classification
    https://www.whatsinproducts.com/
  11. Cosmetic Ingredient Review (CIR)
  12. EPA Chemical and Products Database (CPDat)
  13. Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
    LICENSE
    Copyright (c) 2022 Haz-Map(R). All rights reserved. Unless otherwise indicated, all materials from Haz-Map are copyrighted by Haz-Map(R). No part of these materials, either text or image may be used for any purpose other than for personal use. Therefore, reproduction, modification, storage in a retrieval system or retransmission, in any form or by any means, electronic, mechanical or otherwise, for reasons other than personal use, is strictly prohibited without prior written permission.
    https://haz-map.com/About
    Sodium lauroylsarcosinate
    https://haz-map.com/Agents/17592
  14. Toxin and Toxin Target Database (T3DB)
    LICENSE
    T3DB is offered to the public as a freely available resource. Use and re-distribution of the data, in whole or in part, for commercial purposes requires explicit permission of the authors and explicit acknowledgment of the source material (T3DB) and the original publication.
    http://www.t3db.ca/downloads
    Sodium lauroyl sarcosinate
    http://www.t3db.ca/toxins/T3D3624
  15. NORMAN Suspect List Exchange
    LICENSE
    Data: CC-BY 4.0; Code (hosted by ECI, LCSB): Artistic-2.0
    https://creativecommons.org/licenses/by/4.0/
    NORMAN Suspect List Exchange Classification
    https://www.norman-network.com/nds/SLE/
  16. EPA Safer Choice
    EPA Safer Chemical Ingredients Classification
    https://www.epa.gov/saferchoice
  17. EU Clinical Trials Register
  18. Japan Chemical Substance Dictionary (Nikkaji)
  19. NLM RxNorm Terminology
    LICENSE
    The RxNorm Terminology is created by the National Library of Medicine (NLM) and is in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from NLM. Credit to the U.S. National Library of Medicine as the source is appreciated but not required. The full RxNorm dataset requires a free license.
    https://www.nlm.nih.gov/research/umls/rxnorm/docs/termsofservice.html
  20. SpectraBase
    N-lauroylsarcosine, sodium salt
    https://spectrabase.com/spectrum/GY52EbmgbJl
    N-LAUROYLSARCOSINE, SODIUM SALT
    https://spectrabase.com/spectrum/ucaDHKIh9l
    Na-Fatty Acid-sarcoside (basis lauric acid); lauric acid-sarcoside, Na salt; sarcoside lauric acid, Na salt
    https://spectrabase.com/spectrum/Le1VaJv9SSN
  21. Springer Nature
  22. Wikidata
    sodium lauroyl sarcosinate
    https://www.wikidata.org/wiki/Q309660
  23. Wikipedia
  24. PubChem
  25. Medical Subject Headings (MeSH)
    LICENSE
    Works produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.
    https://www.nlm.nih.gov/copyright.html
  26. GHS Classification (UNECE)
  27. EPA Substance Registry Services
  28. MolGenie
    MolGenie Organic Chemistry Ontology
    https://github.com/MolGenie/ontology/
  29. PATENTSCOPE (WIPO)
CONTENTS