Clevidipine
- Clevidipine
- 167221-71-8
- Clevidipine butyrate
- Cleviprex
- Clevelox
- Create:2005-08-08
- Modify:2025-01-11
- butyroxymethyl methyl 4-(2',3'-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- clevidipine
- Cleviprex
- Clevidipine
- 167221-71-8
- Clevidipine butyrate
- Cleviprex
- Clevelox
- rac-Clevidipine
- Clevidepine
- Clevidepine butyrate
- 166432-28-6
- 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3-methyl 5-[(1-oxobutoxy)methyl] ester
- UNII-19O2GP3B7Q
- 19O2GP3B7Q
- 5-O-(butanoyloxymethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- DTXSID6057661
- H 324/38
- 3-((butyryloxy)methyl) 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- Methyl (1-oxobutoxy)methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
- DTXCID7031450
- H324/38
- H-324/38
- 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, methyl (1-oxobutoxy)methyl ester
- CLEVIDIPINE (MART.)
- CLEVIDIPINE [MART.]
- (Butanoyloxy)methyl methyl (4RS)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- butyroxymethyl methyl 4-(2',3'-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- METHYL 5-{[(BUTANOYLOXY)METHOXY]CARBONYL}-4-(2,3-DICHLOROPHENYL)-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE-3-CARBOXYLATE
- SR-01000945183
- Clevidipine [USAN:INN]
- clevidipinum
- clevipidine
- Clevidipino
- Cleviprex?
- Methyl (1-oxobutoxy)methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dime thyl-3,5-pyridinedicarboxylate
- Cleviprex (TN)
- 3,5-PYRIDINEDICARBOXYLIC ACID, 4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-, 3-METHYL 5-((1-OXOBUTOXY)METHYL) ESTER
- 3-[(Butyryloxy)methyl] 5-Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid 3-Methyl 5-[(1-Oxobutoxy)methyl] Ester; Clevelox; Cleviprex; H 324/38; rac-Clevidipine;
- Clevidipine [INN]
- MFCD00940070
- Clevidipine (Standard)
- Cleviprex (Clevidipine)
- CLEVIDIPINE [MI]
- Clevidipine (USAN/INN)
- CLEVIDIPINE [USAN]
- CLEVIDEPINE [VANDF]
- CLEVIDIPINE [VANDF]
- CLEVIDIPINE [WHO-DD]
- 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid 3-Methyl 5-[(1-Oxobutoxy)methyl] Ester
- SCHEMBL115522
- GTPL7468
- Clevidipine Butyrate;Clevidipine
- CHEMBL1237132
- C08CA16
- CLEVIDIPINE [ORANGE BOOK]
- CHEBI:135738
- KPBZROQVTHLCDU-UHFFFAOYSA-N
- GLXC-10277
- HMS3604H21
- HMS3651G10
- HMS3884L03
- BCP22676
- BCP22687
- EX-A2898
- CLEVIDEPINE BUTYRATE [VANDF]
- CLEVIDIPINE BUTYRATE [VANDF]
- Tox21_113923
- BDBM50088387
- HY-17436R
- s2080
- AKOS015896325
- CCG-269294
- CS-1427
- DB04920
- NCGC00262928-01
- AC-24370
- AS-19935
- CLEVIDIPINE BUTYRATE [ORANGE BOOK]
- HY-17436
- DB-064636
- C3503
- CAS-167221-71-8
- NS00040661
- SW220087-1
- A12130
- D08892
- EN300-119519
- AB01566888_01
- J-520103
- Q5132338
- SR-01000945183-1
- SR-01000945183-2
- BRD-A01563671-001-02-7
- Z1521553844
- 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic Aicd 3-[(Butyryloxy)methyl] 5-Methyl Ester
- Butyroxymethyl methyl 4-(2',3'-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylat
- O3-(butanoyloxymethyl) O5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
478.078644 100
480.07605 62.23
360.014923 30.64
479.081482 29.49
362.011383 19.83
338.03421 100
340.031372 62.81
339.038147 16.85
302.056549 9.70
341.03421 8.52
478.078644 100
480.076050 62.23
360.014923 30.64
479.081482 29.49
362.011383 19.83
338.034210 100
340.031372 62.81
339.038147 16.85
302.056549 9.70
341.034210 8.52
H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
H371 (50%): May cause damage to organs [Warning Specific target organ toxicity, single exposure]
P203, P260, P264, P270, P280, P308+P316, P318, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.
Repr. 2 (100%)
STOT SE 2 (50%)
M Chen, V Vijay, Q Shi, Z Liu, H Fang, W Tong. FDA-Approved Drug Labeling for the Study of Drug-Induced Liver Injury, Drug Discovery Today, 16(15-16):697-703, 2011. PMID:21624500 DOI:10.1016/j.drudis.2011.05.007
M Chen, A Suzuki, S Thakkar, K Yu, C Hu, W Tong. DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug Discov Today 2016, 21(4): 648-653. PMID:26948801 DOI:10.1016/j.drudis.2016.02.015
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=KPBZROQVTHLCDU-UHFFFAOYSA-N
- CAS Common ChemistryLICENSEThe data from CAS Common Chemistry is provided under a CC-BY-NC 4.0 license, unless otherwise stated.https://creativecommons.org/licenses/by-nc/4.0/3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3-methyl 5-[(1-oxobutoxy)methyl] esterhttps://commonchemistry.cas.org/detail?cas_rn=167221-71-8
- DrugBankLICENSECreative Common's Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/legalcode)https://www.drugbank.ca/legal/terms_of_useClevidipinehttps://www.drugbank.ca/drugs/DB04920
- EPA DSSToxCompTox Chemicals Dashboard Chemical Listshttps://comptox.epa.gov/dashboard/chemical-lists/
- European Chemicals Agency (ECHA)LICENSEUse of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.https://echa.europa.eu/web/guest/legal-notice3-((butyryloxy)methyl)-5-methyl-4(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylatehttps://echa.europa.eu/substance-information/-/substanceinfo/100.208.1175-O-(butanoyloxymethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylatehttps://echa.europa.eu/substance-information/-/substanceinfo/100.246.0763-((butyryloxy)methyl)-5-methyl-4(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (EC: 682-702-2)https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/2131055-O-(butanoyloxymethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (EC: 814-032-5)https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/254111
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- ChEBI
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- ChemIDplusClevidipine [USAN:INN]https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0167221718ChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
- ClinicalTrials.govLICENSEThe ClinicalTrials.gov data carry an international copyright outside the United States and its Territories or Possessions. Some ClinicalTrials.gov data may be subject to the copyright of third parties; you should consult these entities for any additional terms of use.https://clinicaltrials.gov/ct2/about-site/terms-conditions#Use
- Comparative Toxicogenomics Database (CTD)LICENSEIt is to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of NC State University.http://ctdbase.org/about/legal.jsp
- Drug Gene Interaction database (DGIdb)LICENSEThe data used in DGIdb is all open access and where possible made available as raw data dumps in the downloads section.http://www.dgidb.org/downloadsCLEVIDIPINEhttps://www.dgidb.org/drugs/rxcui:233603
- Therapeutic Target Database (TTD)Clevidipine butyratehttps://idrblab.net/ttd/data/drug/details/D09ELP
- DailyMed
- Drug Induced Liver Injury Rank (DILIrank) DatasetLICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linking
- European Medicines Agency (EMA)LICENSEInformation on the European Medicines Agency's (EMA) website is subject to a disclaimer and copyright and limited reproduction notices.https://www.ema.europa.eu/en/about-us/legal-noticeClevidipine butyrate (P/0009/2014)https://www.ema.europa.eu/en/medicines/human/paediatric-investigation-plans/emea-000282-pip01-08-m02
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- EU Clinical Trials Register
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- Japan Chemical Substance Dictionary (Nikkaji)
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- Metabolomics Workbench
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- Springer Nature
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- Wikidataclevidipinehttps://www.wikidata.org/wiki/Q5132338
- WikipediaClevidipinehttps://en.wikipedia.org/wiki/Clevidipine
- Wiley
- PubChem
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- GHS Classification (UNECE)GHS Classification Treehttp://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html
- MolGenieMolGenie Organic Chemistry Ontologyhttps://github.com/MolGenie/ontology/
- PATENTSCOPE (WIPO)SID 389127566https://pubchem.ncbi.nlm.nih.gov/substance/389127566
- NCBI