2,3,3,3-Tetrafluoro-2-(heptafluoropropoxy)propanoic acid
- C3F7OCF(CF3)COOH
- C6HF11O3
- 13252-13-6
- PERFLUORO(2-METHYL-3-OXAHEXANOIC) ACID
- 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid
- GenX
- Perfluoro-2-methyl-3-oxahexanoic acid
- Create:2005-03-26
- Modify:2025-01-04
- 2,2,3-trifluoro-3-(trifluoromethyl)oxirane
- 2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3,heptafluoropropoxy)propanoic acid
- 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acid
- 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate
- 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid
- 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid
- ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate
- ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate
- ammonium 2-(perfluoropropoxy)perfluoropropionate
- ammonium perfluoro(2-methyl-3-oxahexanoic) acid
- ammonium perfluoro-2-methyl-3-oxahexanoate
- azanium;2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoate
- C6HF11O3.H3N
- GenX ammonium perfluoro-2-methyl-3-oxahexanoate
- GenX perfluoro(2-propoxypropanoate)
- GenX perfluoro-2-methyl-3-oxahexanoic acid
- GenX potassium salt
- GenX-K
- GenX-Na
- hexafluoroepoxypropane
- hexafluoropropene oxide
- hexafluoropropylene oxide
- hexafluoropropylene oxide dimer acid
- hexafluoropropylene oxide tetramer acid
- hexafluoropropylene oxide trimer acid
- HFPO hexafluoropropylene oxide
- HFPO-DA
- HFPO-DA hexafluoropropylene oxide dimer acid
- HFPO-TA
- HFPO-TA hexafluoropropylene oxide trimer acid
- HFPO-TeA
- HFPO-TeA hexafluoropropylene oxide tetramer acid
- HFPO-TrA
- HFPO-TrA hexafluoropropylene oxide trimer acid
- HFPO2 compound
- per- and polyfluoroalkyl ether acids
- perfluoro(2-propoxypropanoate)
- perfluoro-2-(propyloxy)propionic acid
- perfluoro-2-methyl-3-oxahexanoic acid
- perfluoro-2-propoxypropanoic acid
- perfluoro-2-propoxypropionic acid
- PFEA per- and polyfluoroalkyl ether acids
- potassium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate
- propanoic acid, 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-, potassium salt (1:1)
- propanoic acid, 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-, sodium salt (1:1)
- sodium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate
- 13252-13-6
- PERFLUORO(2-METHYL-3-OXAHEXANOIC) ACID
- 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid
- GenX
- Perfluoro-2-methyl-3-oxahexanoic acid
- HFPO-DA
- 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acid
- hexafluoropropylene oxide dimer acid
- UNDECAFLUORO-2-METHYL-3-OXAHEXANOIC ACID
- Perfluoro(2-methyl-3-oxahexanoic)acid
- R8C5T5N5HN
- perfluoro-2-propoxypropionic acid
- DTXSID70880215
- 2,3,3,3-tetrafluoro-2-(perfluoropropoxy)propanoic acid
- 2,3,3,3-Tetrafluoro-2-(heptafluoropropoxy)propionic acid
- 2-(Heptafluoropropoxy)-2,3,3,3-tetrafluoropropionic acid
- NSC676909
- 2,3,3,3-Tetrafluoro-2-(heptafluoropropoxy)-propanoic acid
- 2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3,heptafluoropropoxy)propanoic Acid (~90%)
- EINECS 236-236-8
- HFPO-DA (GenX)
- HFPO-DA (Gen X)
- UNII-R8C5T5N5HN
- OPFLCA_i n=3 (GenX)
- OPFLCA_i, n=3 (GenX)
- SCHEMBL2887903
- CHEMBL2008338
- DTXSID5040839
- perfluoro-2-propoxypropanoic acid
- FRD-903
- CHEBI:143205
- DTXSID301028719
- Perfluoro-alpha-propoxypropionic acid
- BBL102039
- MFCD00236734
- STL555838
- perfluoro-2-(propyloxy)propionic acid
- 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propionic acid
- AKOS016016018
- Propanoic acid, 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-
- (+)-Perfluoro(2-propoxypropionic) acid
- (-)-Perfluoro(2-propoxypropionic) acid
- MS-20355
- NCI60_027327
- Hexafluoropropylene oxide dimer acid (Gen X)
- NS00011372
- Perfluoro(2-propoxypropionic) acid, (+/-)-
- Perfluoro-2-propoxypropanoic acid (PFPrOPrA)
- G72649
- (+/-)-PERFLUORO(2-PROPOXYPROPIONIC) ACID
- EN300-18553200
- Q29387971
- Undecafluoro-2-methyl-3-oxahexanoic acid, 50 ug/ml in methanol
- PROPANOIC ACID, 2,3,3,3-TETRAFLUORO-2-(HEPTAFLUOROPROPOXY)-
- PROPIONIC ACID, 2,3,3,3-TETRAFLUORO-2-(HEPTAFLUOROPROPOXY)-
- Perfluoro-2-propoxypropanoic acid (PFPrOPrA ) 100 microg/mL in Methanol:Water
- 2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acid compound with N,N,N-triethylamine (1:1)
- 75579-39-4
- 75579-40-7
126.89 Ų [M-H-CO2]-
198.61 Ų [2M-H]-
PFAS -> Perfluoroethercarboxylic acids
PFAS -> Negative ionization
• Processing aid [Ref: DEP. 2011. Consent Order Issued under the Water Pollution Control Act to E. .I Du Pont de Nemours and Company.]
• All other basic organic chemical manufacturing - processing aid [Ref: USEPA]
- Processing aids, not otherwise listed
- Intermediates
2019: <1,000,000 lb
2018: <1,000,000 lb
2017: <1,000,000 lb
2016: <1,000,000 lb
H302 (68.7%): Harmful if swallowed [Warning Acute toxicity, oral]
H314 (72.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H318 (67.9%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
H335 (68.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P363, P403+P233, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)
Aggregated GHS information provided per 134 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Reported as not meeting GHS hazard criteria per 37 of 134 reports by companies. For more detailed information, please visit ECHA C&L website.
There are 4 notifications provided by 97 of 134 reports by companies with hazard statement code(s).
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.
Acute Tox. 4 (68.7%)
Skin Corr. 1B (72.4%)
Eye Dam. 1 (67.9%)
STOT SE 3 (68.7%)
Hazard Traits - Toxicity Undefined
Authoritative List - CECBP - Priority Chemicals
Report - if used as a fragrance or flavor ingredient
Substance: 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid
EC: 236-236-8
Date of inclusion: >16-Jul-2019
Reason for inclusion: Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health); Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)
Patents are available for this chemical structure:
https://patentscope.wipo.int/search/en/result.jsf?inchikey=CSEBNABAWMZWIF-UHFFFAOYSA-N
- Baker Lab, Chemistry Department, The University of North Carolina at Chapel HillHFPO-DA (GenX)CCS Classification - Baker Labhttps://tarheels.live/bakerlab/
- NORMAN Suspect List ExchangeLICENSEData: CC-BY 4.0; Code (hosted by ECI, LCSB): Artistic-2.0https://creativecommons.org/licenses/by/4.0/Hexafluoropropylene oxide dimer acidNORMAN Suspect List Exchange Classificationhttps://www.norman-network.com/nds/SLE/
- USGS Health-Based Screening Levels for Evaluating Water-Quality DataLICENSEhttps://www.usgs.gov/legalHexafluoropropylene oxide dimer acid (HFPO-DA)https://water.usgs.gov/water-resources/hbsl/index.html
- California Safe Cosmetics Program (CSCP) Product DatabasePerfluoro-2-methyl-3-oxahexanoic acid (GenX)https://www.cdph.ca.gov/Programs/CCDPHP/DEODC/OHB/CSCP/Pages/About-CSCP.aspx
- European Chemicals Agency (ECHA)LICENSEUse of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source: European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.https://echa.europa.eu/web/guest/legal-notice2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acidhttps://echa.europa.eu/substance-information/-/substanceinfo/100.032.9282,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid (EC: 236-236-8)https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/58242
- CAS Common ChemistryLICENSEThe data from CAS Common Chemistry is provided under a CC-BY-NC 4.0 license, unless otherwise stated.https://creativecommons.org/licenses/by-nc/4.0/2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acidhttps://commonchemistry.cas.org/detail?cas_rn=13252-13-6
- ChemIDplusChemIDplus Chemical Information Classificationhttps://pubchem.ncbi.nlm.nih.gov/source/ChemIDplus
- EPA Chemical Data Reporting (CDR)LICENSEThe U.S. Government retains a nonexclusive, royalty-free license to publish or reproduce these documents, or allow others to do so, for U.S. Government purposes. These documents may be freely distributed and used for non-commercial, scientific and educational purposes.https://www.epa.gov/web-policies-and-procedures/epa-disclaimers#copyrightPropanoic acid, 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-https://www.epa.gov/chemical-data-reporting
- EPA Chemicals under the TSCAPropanoic acid, 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-https://www.epa.gov/chemicals-under-tscaEPA TSCA Classificationhttps://www.epa.gov/tsca-inventory
- EPA DSSTox(-)-Perfluoro(2-propoxypropionic) acidhttps://comptox.epa.gov/dashboard/DTXSID301028719(+)-Perfluoro(2-propoxypropionic) acidhttps://comptox.epa.gov/dashboard/DTXSID5040839Perfluoro-2-methyl-3-oxahexanoic acidhttps://comptox.epa.gov/dashboard/DTXSID70880215CompTox Chemicals Dashboard Chemical Listshttps://comptox.epa.gov/dashboard/chemical-lists/
- FDA Global Substance Registration System (GSRS)LICENSEUnless otherwise noted, the contents of the FDA website (www.fda.gov), both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Credit to the U.S. Food and Drug Administration as the source is appreciated but not required.https://www.fda.gov/about-fda/about-website/website-policies#linkingPerfluoro(2-propoxypropionic) acid, (±)-https://gsrs.ncats.nih.gov/ginas/app/beta/substances/R8C5T5N5HN
- Risk Assessment Information System (RAIS)LICENSEThis work has been sponsored by the U.S. Department of Energy (DOE), Office of Environmental Management, Oak Ridge Operations (ORO) Office through a joint collaboration between United Cleanup Oak Ridge LLC (UCOR), Oak Ridge National Laboratory (ORNL), and The University of Tennessee, Ecology and Evolutionary Biology, The Institute for Environmental Modeling (TIEM). All rights reserved.https://rais.ornl.gov/Hexafluoropropylene oxide dimer acid (HFPO-DA)https://rais.ornl.gov/cgi-bin/tools/TOX_search
- ChEBI2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acidhttps://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:143205
- ChEMBLLICENSEAccess to the web interface of ChEMBL is made under the EBI's Terms of Use (http://www.ebi.ac.uk/Information/termsofuse.html). The ChEMBL data is made available on a Creative Commons Attribution-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-sa/3.0/).http://www.ebi.ac.uk/Information/termsofuse.html
- EPA Regional Screening Levels for Chemical Contaminants at Superfund SitesHexafluoropropylene oxide dimer acid (HFPO-DA)https://epa-prgs.ornl.gov/cgi-bin/chemicals/csl_searchHexafluoropropylene oxide dimer acid (HFPO-DA)https://epa-prgs.ornl.gov/cgi-bin/chemicals/csl_search?tool=rml
- Japan Chemical Substance Dictionary (Nikkaji)
- Suuberg Lab, School of Engineering, Brown University
- Springer Nature
- Wikidata2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acidhttps://www.wikidata.org/wiki/Q29387971
- Wikipedia
- PubChemPFAS and Fluorinated Compounds in PubChemhttps://gitlab.com/uniluxembourg/lcsb/eci/pubchem-docs/-/raw/main/pfas-tree/PFAS_Tree.pdf?inline=false
- Medical Subject Headings (MeSH)LICENSEWorks produced by the U.S. government are not subject to copyright protection in the United States. Any such works found on National Library of Medicine (NLM) Web sites may be freely used or reproduced without permission in the U.S.https://www.nlm.nih.gov/copyright.htmlammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoatehttps://www.ncbi.nlm.nih.gov/mesh/2015972
- GHS Classification (UNECE)GHS Classification Treehttp://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html
- EPA Substance Registry ServicesEPA SRS List Classificationhttps://sor.epa.gov/sor_internet/registry/substreg/LandingPage.do
- MolGenieMolGenie Organic Chemistry Ontologyhttps://github.com/MolGenie/ontology/
- PATENTSCOPE (WIPO)SID 403385290https://pubchem.ncbi.nlm.nih.gov/substance/403385290