ximelagatran - Compound Summary (CID 9574101) Also known as: Exanta, Exarta, H 376/95, Exanta (TN), H 376-95, H 37695, Ximelagatran [USAN:INN], Ximelagatran (JAN/USAN/INN), UNII-49HFB70472 Molecular Formula: C 24H 35N 5O 5 Molecular Weight: 473.5652 InChIKey: ZXIBCJHYVWYIKI-PZJWPPBQSA-N Ximelagatran (Exanta® or Exarta®, H 376/95) is an anticoagulant that has been investigated extensively as a replacement for warfarin that would overcome the problematic dietary, drug interaction, and monitoring issues associated with warfarin therapy. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries where the drug had been approved. From: DrugBank |
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