Amsacrine - Compound Summary (CID 88124) Also known as: Amsacrine lactate, m-AMSA lactate, NSC 141549, Methanesulfon-m-anisidide, 4'-(9-acridinylamino)-, compd. with lactic acid Molecular Formula: C 24H 25N 3O 6S Molecular Weight: 483.5368 InChIKey: NYGZSXVEKMITFN-UHFFFAOYSA-N Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects. From: MeSH |
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