tolcapone - PubChem

tolcapone - Compound Summary (CID 4659569) Also known as: Tasmar, 134308-13-7, Ro 40-7592, Ro-40-7592, 3,4-Dihydroxy-4'-methyl-5-nitrobenzophenone Molecular Formula: C₁₄H₁₁NO₅ Molecular Weight: 273.24084 InChIKey: MIQPIUSUKVNLNT-UHFFFAOYSA-N Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity. [Wikipedia] From: DrugBank View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 3D ASN.1 Text: Display 3D ASN.1 Text: Save 3D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 3D XML: Display 3D XML: Save 2D SDF: Display 2D SDF: Save 3D SDF: Display 3D SDF: Save BioActivity, this compound BioActivity, with similar compounds BioActivity, with similar conformers
Show subcontent titlesHide subcontent titlesTable of Contents Identification Depositor-Supplied Synonyms Compound Information Related Records Related Compounds with Annotation Related Compounds Related Substances Use and Manufacturing Medication Information Patents Pharmacology Pharmacological Action Literature Depositor Provided PubMed Citations NLM Curated PubMed Citations Patents Depositor-Supplied Patent Identifiers Biomolecular Interactions and Pathways Protein Bound 3-D Structures Interactions Target Enzyme Action General Function Specific Function Gene Name GenBank Gene GenBank Protein References Biological Test Results BioAssay Results Classification Ontologies Substance Categorization Classification Chemical and Physical Properties Computed Properties Default display	2D Structure 3D Conformer
Identification Help top of page Related Records Help top of page show first sub-section only Use and Manufacturing Help top of page show first sub-section only Pharmacology Help top of page Literature Help top of page show first sub-section only Patents Help top of page Biomolecular Interactions and Pathways Help top of page show first sub-section only Biological Test Results Help top of page Data Analysis Data Download BioActivity Summary: This Compound with Similar Compounds with Similar Conformers Classification Help top of page show first sub-section only Chemical and Physical Properties Help top of page

_

_