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Compound Summary for: CID 14982

Glycyrrhizic Acid

Also known as: Glycyrrhizinic acid; glycyrrhizin; Glycyron; glyzyrrhizin; Glycyrrizin; Glycyrrhetinic acid glycoside; 18-beta-Glycyrrhizic acid; 1405-86-3
Molecular Formula: C42H62O16   Molecular Weight: 822.93208   InChIKey: LPLVUJXQOOQHMX-QWBHMCJMSA-N
A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.   From: MeSH
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