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Compound Summary for: CID 126941

Methotrexate

Also known as: Amethopterin; Rheumatrex; Abitrexate; Mexate; Trexall; 59-05-2; Methylaminopterin; Ledertrexate; Antifolan
Molecular Formula: C20H22N8O5   Molecular Weight: 454.43928   InChIKey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.   From: MeSH
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