998816
1
2
3
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5
6
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9
10
11
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17
18
19
20
21
22
23
24
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26
27
28
29
30
31
32
33
34
35
36
37
38
17
16
9
9
9
9
8
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
4
5
6
7
8
8
8
9
10
10
10
11
11
12
12
12
13
13
14
14
14
15
15
16
17
19
20
20
22
22
23
23
24
24
25
25
26
21
17
17
19
19
18
9
13
14
16
11
18
32
21
33
20
21
34
15
17
18
27
28
16
29
19
30
31
22
23
24
35
25
36
26
37
26
38
1
2
1
1
1
1
2
1
1
1
2
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
2
1
1
1
2
1
2
1
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
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26
27
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38
-7.6368
-2.9179
1.2184
0.3084
6.9283
6.3671
1.9059
2.8933
4.1598
-0.0911
-0.857
-2.4428
2.5906
1.9839
3.7543
4.6861
1.2539
1.2825
6.1017
-3.6893
-2.0904
-3.7086
-4.8577
-4.9354
-6.0843
-6.1233
1.2849
2.5736
3.9052
0.9435
6.401
-0.579
-0.4851
-1.6496
-2.789
-4.9059
-4.9504
-7.0025
1.9963
-3.2658
3.0007
1.043
0.5758
-0.6249
-2.5744
0.1357
-0.2749
-1.5667
-2.4514
-0.769
1.2649
-0.6415
1.6306
0.6468
1.8872
-1.7081
0.552
-0.1053
-2.0915
1.2638
-0.842
1.9169
-0.1888
1.1906
0.0462
-1.1237
2.4859
2.186
1.3677
-0.9064
-3.3889
-0.1595
1.8386
-1.9151
2.9923
-0.7684
-0.2836
1.3336
0.7252
0.4431
-0.5045
1.2228
-0.1631
-0.7468
-0.6219
-0.7837
-0.0618
0.2195
-0.0607
-1.5814
0.5708
0.1891
-0.0636
-0.7734
0.5827
0.0986
0.4688
-0.1026
0.1849
-0.2212
0.0661
-0.1369
-2.0657
-2.369
1.2139
-1.0687
1.2469
-1.3796
0.0512
0.0332
-0.1693
0.2782
-0.3791
0.1202
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
000F3DA000000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
52.8071
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
42.181
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10674148 151 18260546737378258714
11646440 116 17989215870848720081
11719270 70 18272086067975677046
12107183 9 18260257530732661946
12596602 18 15141257558881589173
12633257 1 17603866745075289863
12778500 126 17458620073487504304
12838862 33 18270101461966605433
13402501 40 18412545409853929749
14466204 15 18410855490557118330
14681490 219 18131067079322857625
14790565 3 17259619774085383648
15183329 4 18410575067663012937
15238133 3 18260274066050465062
15351339 4 18197772203533179441
15537594 2 12613026236468954496
18608769 82 18411421756979685803
20567600 254 18261385638436856055
20715895 44 18412546500675142801
21033648 29 18058999713916969602
21279426 13 18268433442739418894
21298829 104 18201724999126591489
21315763 129 18339924947588180895
21774942 28 17417256411786096889
23227448 37 18271807964949363607
23559900 14 18342731958025128761
2838139 119 18342733053019456967
335352 9 18412545422902069932
3680242 22 18336830788269809970
4073 2 18188492500923172240
4093350 32 17131557128918523949
4325135 7 18130784595202405815
508706 21 18336547218008525911
5385378 56 18262237707802756587
5969126 39 18126281077148492863
59755656 215 18412546483268504812
59755656 520 18113892780463078707
6328613 192 18262524818251339372
9981440 41 18260835908314605947
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
480.92
17.61
3.13
0.97
2.49
1.48
-0.05
-9.26
1.28
2.52
0.71
-0.61
0.33
1.35
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
994.812
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
279
Conformer
RMSD
7
2009.12.11
1
Diverse Conformer
ID List
6
2012.02.08
1
28
18
79
15
77
22
8
73
68
67
52
49
32
58
47
24
16
64
56
27
19
54
20
40
57
43
71
11
72
39
17
48
76
13
29
6
63
25
70
50
37
38
41
34
59
12
45
7
46
55
78
23
26
31
53
60
9
44
65
62
5
35
61
51
2
74
14
21
69
75
3
33
4
10
36
42
66
30
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
34
1 -0.18
10 -0.43
11 -0.43
12 -0.55
13 -0.33
14 0.32
15 -0.15
16 0.11
17 0.86
18 0.57
19 0.86
2 -0.38
20 0.12
21 0.5
22 -0.15
23 -0.15
24 -0.15
25 -0.15
26 0.18
29 0.15
3 -0.34
32 0.37
33 0.37
34 0.37
35 0.15
36 0.15
37 0.15
38 0.15
4 -0.34
5 -0.34
6 -0.34
7 -0.57
8 0.31
9 -0.71
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
9
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
8
1 10 donor
1 11 donor
1 12 donor
1 2 acceptor
1 7 acceptor
1 9 acceptor
5 8 9 13 15 16 rings
6 20 22 23 24 25 26 rings
26
0
0
0
0
0
0
0
1
6