9937660 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 17 16 8 8 8 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 3 3 5 5 6 6 6 7 7 7 8 8 9 9 10 10 10 11 11 11 12 12 13 13 14 14 14 15 16 16 17 17 18 19 19 20 20 21 21 22 22 23 24 26 26 27 28 28 29 29 30 30 32 33 33 33 34 34 35 35 36 36 37 37 38 38 39 31 4 12 13 15 17 30 33 10 11 14 25 26 55 23 27 25 27 12 42 43 13 40 41 46 47 44 45 15 48 49 16 18 50 18 19 51 20 22 21 52 23 25 24 53 24 54 28 29 56 31 57 32 58 31 32 59 34 60 61 35 36 37 62 38 63 39 64 39 65 66 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2 1 1 2 1 1 1 2 1 2 1 1 1 2 1 1 1 1 2 1 2 1 1 1 1 1 2 1 1 1 2 1 2 1 1 1 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 12.106 2.5878 6.0148 2 13.8495 3.7634 10.4088 10.4204 11.3264 4.1701 2.7688 3.5823 2.181 4.3511 5.3457 5.8457 6.9283 6.8238 7.7944 8.6604 9.5264 7.7944 9.5264 8.6604 10.4204 11.269 11.3264 11.2574 12.1407 12.9894 12.1176 13.0009 14.7213 15.5815 15.5699 16.4532 16.4301 17.3134 17.3018 2.9397 2.2116 4.6008 4.6841 1.7504 1.667 3.4114 4.1396 4.522 3.7939 5.5935 7.2846 8.6604 7.2574 8.6604 9.8683 11.8622 10.7169 12.1479 13.5414 15.1253 14.3283 15.0294 16.4604 16.4229 17.8539 17.8352 -2.7695 -1.374 1.6916 -2.183 -1.7896 0.244 0.2503 3.3196 1.7641 -0.6695 0.3485 -1.4786 -0.4605 1.053 0.9485 0.0825 1.2849 0.2904 1.7849 1.2849 1.7849 2.7849 2.7849 3.2849 1.2502 -0.2597 2.8057 -1.2596 0.2303 -1.2796 -1.7696 -0.2797 -1.2997 -1.8096 -2.8096 -1.3197 -3.3196 -1.8297 -2.8296 0.9445 0.6203 -1.1155 -0.3228 -0.0145 -0.8072 -2.0745 -1.7504 1.649 1.3248 -0.4839 -0.1245 0.6649 3.0949 3.9049 -0.0535 3.1178 -1.5634 0.8502 0.0241 -0.8294 -0.8201 -3.1134 -0.6997 -3.9395 -1.5259 -3.1458 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 3 3 8 8 9 9 15 16 17 19 19 20 21 21 22 23 26 26 28 29 30 30 34 34 35 36 37 38 15 17 23 27 25 27 16 18 18 20 22 21 23 25 24 24 28 29 31 32 31 32 35 36 37 38 39 39 0 Compound Canonicalized 5 2010.07.16 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 794 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 8 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 1 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 8 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371E07BB0004400000000000000000000000001200000003C78C1020000000000B1FC00001E06100000000C0EE5DE26B5F6F7C8144AA803A6736440C288293527F009D821BE6FD88E2EF3C5FFFB873D28ECD013F8E9A7B8D9F39E08400200020208001080040004041000000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 N-(4-benzyloxy-3-chloro-phenyl)-6-[5-[(1-oxo-1,4-thiazinan-4-yl)methyl]-2-furyl]quinazolin-4-amine IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 N-(3-chloro-4-phenylmethoxyphenyl)-6-[5-[(1-oxo-1,4-thiazinan-4-yl)methyl]-2-furanyl]-4-quinazolinamine IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 N-(3-chloro-4-phenylmethoxyphenyl)-6-[5-[(1-oxo-1,4-thiazinan-4-yl)methyl]furan-2-yl]quinazolin-4-amine IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 N-(3-chloranyl-4-phenylmethoxy-phenyl)-6-[5-[(1-oxidanylidene-1,4-thiazinan-4-yl)methyl]furan-2-yl]quinazolin-4-amine IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 (4-benzoxy-3-chloro-phenyl)-[6-[5-[(1-keto-1,4-thiazinan-4-yl)methyl]-2-furyl]quinazolin-4-yl]amine InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C30H27ClN4O3S/c31-26-17-23(7-10-29(26)37-19-21-4-2-1-3-5-21)34-30-25-16-22(6-9-27(25)32-20-33-30)28-11-8-24(38-28)18-35-12-14-39(36)15-13-35/h1-11,16-17,20H,12-15,18-19H2,(H,32,33,34) InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 BDCAOKLPNVNFEL-UHFFFAOYSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 4.9 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 558.149239 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C30H27ClN4O3S Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 559.07838 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 C1CS(=O)CCN1CC2=CC=C(O2)C3=CC4=C(C=C3)N=CN=C4NC5=CC(=C(C=C5)OCC6=CC=CC=C6)Cl SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 C1CS(=O)CCN1CC2=CC=C(O2)C3=CC4=C(C=C3)N=CN=C4NC5=CC(=C(C=C5)OCC6=CC=CC=C6)Cl Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 99.7 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 558.149239 39 0 0 0 0 0 0 0 1 3