9916949 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 17 16 8 8 8 8 8 8 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 3 4 4 5 6 6 7 7 8 9 9 10 10 10 11 11 11 12 12 12 12 13 13 13 14 14 14 15 15 15 16 16 16 17 17 18 18 18 19 19 19 20 21 23 23 24 25 25 26 26 28 28 29 29 30 31 32 32 33 33 33 35 35 36 36 37 38 40 40 40 41 41 41 42 42 42 34 20 22 24 40 31 41 27 37 42 39 73 39 21 22 22 27 58 26 28 33 13 14 18 43 16 44 45 15 46 47 17 50 51 17 48 49 52 53 19 54 55 20 56 57 21 23 24 25 32 31 59 27 30 29 35 30 36 60 34 34 61 39 62 63 38 64 37 65 38 66 67 68 69 70 71 72 74 75 76 1 1 1 1 1 1 1 2 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2 2 1 1 1 2 2 1 1 1 1 2 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 14.2688 10.0817 10.8237 14.4779 8.4939 2.866 6.3638 5.0746 10.0817 8.4939 6.4103 12.5463 13.4598 12.4417 13.2508 14.2688 14.1643 11.7373 11.8418 11.0328 11.0328 9.4939 11.8418 11.7373 12.7553 6.9939 7.9939 5.4641 5.4641 6.4103 13.5644 12.5463 6.721 13.4598 4.5981 4.5981 3.732 3.732 6.0531 10.7192 15.2869 2 11.9799 13.1131 13.9058 12.17 11.8458 14.5406 14.8648 13.5975 12.8048 14.7828 14.3143 11.4655 11.1413 12.1136 12.4378 8.1839 12.8201 6.6029 12.4815 7.2679 7.1035 4.5981 4.5981 3.1951 10.1026 10.6544 11.3358 14.9225 15.7885 15.6513 5.9497 2.31 1.4631 1.69 -3.4981 0.162 -3.136 -1.5091 1.085 -0.781 3.6691 2.5124 -1.456 -0.647 1.0238 2.0231 1.6164 3.0176 3.6054 2.2041 3.1987 1.4353 0.4408 -0.147 -1.147 -0.647 -1.7348 -2.7293 -1.328 0.219 0.219 0.719 -0.281 -0.5857 -1.9158 -3.3171 1.9743 -2.9104 1.219 -0.781 -0.281 0.719 2.7186 -4.1306 -2.0969 -0.281 2.2753 1.1024 1.1857 3.5749 2.8467 1.6469 2.375 4.1194 4.0361 3.1554 3.8002 1.9926 1.2644 -0.1165 0.6117 -1.1839 -0.7114 -1.175 -3.9337 1.6823 2.4622 1.839 -1.401 1.029 -4.0658 -4.7472 -4.1954 -2.5985 -2.4613 -1.5953 4.1306 0.256 0.029 -0.8179 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 2 2 9 9 11 11 20 23 23 24 25 26 28 28 29 29 31 32 35 36 37 20 22 21 22 26 28 21 24 25 32 31 30 29 35 30 36 34 34 38 37 38 0 Compound Canonicalized 5 2010.07.16 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 912 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 8 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 2 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 11 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371F07B3800440000000000000000000000000162C000003060C000000000005801FC00001E06100800000D0EC1DE2633DFF3CC1608AC0325F27C0082F8A9672F7909D835BE6FD88E66F3E5BFBB9431286EC113D8E9A7F8D9F39E05400101000A08000A80020200141000000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 2-[2-[[4-(4-chloro-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)thiazol-2-yl]carbamoyl]-5-methoxy-indol-1-yl]acetic acid IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 2-[2-[[[4-(4-chloro-2,5-dimethoxyphenyl)-5-(2-cyclohexylethyl)-2-thiazolyl]amino]-oxomethyl]-5-methoxy-1-indolyl]acetic acid IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 2-[2-[[4-(4-chloro-2,5-dimethoxyphenyl)-5-(2-cyclohexylethyl)-1,3-thiazol-2-yl]carbamoyl]-5-methoxyindol-1-yl]acetic acid IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 2-[2-[[4-(4-chloranyl-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)-1,3-thiazol-2-yl]carbamoyl]-5-methoxy-indol-1-yl]ethanoic acid IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 2-[2-[[4-(4-chloro-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)thiazol-2-yl]carbamoyl]-5-methoxy-indol-1-yl]acetic acid InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C31H34ClN3O6S/c1-39-20-10-11-23-19(13-20)14-24(35(23)17-28(36)37)30(38)34-31-33-29(21-15-26(41-3)22(32)16-25(21)40-2)27(42-31)12-9-18-7-5-4-6-8-18/h10-11,13-16,18H,4-9,12,17H2,1-3H3,(H,36,37)(H,33,34,38) InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 HYGJUCCSZDXPRF-UHFFFAOYSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 7.8 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 611.185685 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C31H34ClN3O6S Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 612.13616 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 COC1=CC2=C(C=C1)N(C(=C2)C(=O)NC3=NC(=C(S3)CCC4CCCCC4)C5=CC(=C(C=C5OC)Cl)OC)CC(=O)O SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 COC1=CC2=C(C=C1)N(C(=C2)C(=O)NC3=NC(=C(S3)CCC4CCCCC4)C5=CC(=C(C=C5OC)Cl)OC)CC(=O)O Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 140 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 611.185685 42 0 0 0 0 0 0 0 1 3