9871754 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 9 9 9 9 9 9 8 8 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 4 5 6 7 8 9 9 9 10 10 10 11 11 12 12 13 13 14 14 15 15 15 17 17 18 19 19 21 21 21 22 22 23 23 23 24 24 25 25 26 26 27 27 28 28 29 29 30 31 31 32 32 32 33 34 35 38 38 38 36 36 36 37 37 37 16 20 12 20 21 15 16 23 18 35 13 16 14 17 18 22 19 39 40 26 27 20 24 25 41 42 43 31 44 47 48 49 28 45 29 46 33 50 34 51 30 37 30 36 52 35 53 33 34 38 54 55 56 57 58 59 1 1 1 1 1 1 2 2 1 1 1 1 1 1 1 2 2 1 1 1 2 1 1 1 1 2 1 1 2 1 1 1 1 2 1 1 1 1 1 1 2 1 1 1 2 1 2 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 -3.2048 -5.2328 -3.8166 -3.965 -4.3889 -5.7907 0.8384 5.8761 3.5743 0.3548 6.1641 2.4329 2.4717 3.7859 -0.9329 1.134 1.2497 4.9241 -2.0642 4.841 3.4772 3.9611 0.774 -2.7098 -2.4548 0.8991 0.4586 -3.7608 -3.5059 -4.1588 5.2187 -1.0644 -0.2629 -0.7036 6.2794 -3.9314 -4.4592 -2.3073 -0.9051 -1.0858 2.8168 3.0797 4.4514 3.1273 -2.3981 -1.9442 0.0338 1.7519 0.814 1.5141 0.7362 -4.9778 5.3588 -0.5319 -1.3193 7.2792 -2.5483 -2.1792 -3.1618 -0.9656 -0.8935 -2.3289 1.9061 -0.2156 1.2317 1.1041 1.9371 1.679 2.13 -0.3697 0.8789 -0.3346 -0.8028 2.6871 1.3772 -1.1331 -0.0255 1.7414 1.2831 2.9784 -2.0331 2.4138 1.79 0.8266 -2.0334 -0.9785 0.9115 -0.052 -0.0096 -2.4243 -2.6451 -2.7929 -1.7379 -1.5635 -1.037 0.957 -3.4564 2.9078 3.6504 3.6316 2.84 3.4681 -2.711 2.5133 0.7987 2.0097 2.0173 3.5009 -2.1586 -0.2948 -0.6949 -3.3755 -3.4951 -1.6179 -1.8193 -4.0022 -4.1928 -2.8188 3.3219 2.5564 1.7421 -3.2355 -3.0833 -2.2655 2.3472 0.4851 0.8316 0.3134 -0.7193 0.6709 0.0624 -0.4417 0.7065 1.1858 -0.0806 -0.2921 0.4236 0.3742 1.496 -1.0879 -1.057 -0.8064 1.3943 0.9169 -1.2115 -1.0693 1.1314 -0.1004 -1.5422 -0.351 0.781 -1.3473 -1.3351 2.1674 -2.3864 -0.4956 1.7812 0.2046 0.918 2.5061 1.579 -1.2514 -1.5551 2.3529 -1.7521 -1.3274 -1.1822 1.8046 -2.0083 -0.3056 -2.0428 1.5656 -2.2347 -1.6689 0.4222 -1.2959 -0.7406 Conformer ID 11 2.1 PubChem ncbi.nlm.nih.gov 2009.12.11 0096A18A00000001 Energy MMFF94 NoEstat 7 1.7.2 Szybki openeye.com 2012.11.26 103.4699 Feature Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 35.563 Fingerprint Shape 2 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 10076449 9 18057631818948021758 11513181 2 17557709053710410670 11578080 2 17024314016035846331 12422481 6 18200051640648465738 12788726 201 16342885165124664576 13383661 66 17194580319321771367 13402501 40 18338532883883249787 13583140 156 17967808357864890714 14040221 97 18046634674829156108 14068700 675 15625356005846886637 14294032 229 16515686590585320173 14747281 78 18048590422826527965 15324884 4 18189606302082001097 15484559 13 16038051853576270745 15781502 13 13756354558005816045 16067689 68 15194162605204087806 17349148 13 17274832307475491042 17492 54 18267846338544098119 20511986 3 14056992823918580085 20775438 99 16982600941190137359 21033648 144 18201999971247892142 21033648 29 18260261958200092685 21033650 10 16733557026187419648 22182313 1 18335140912049674600 22393880 68 18198321984504687941 2818148 4 18051149269276781503 4015057 19 18060134362619530888 4112364 45 13697257775724679189 460360 51 18260255353015606466 469060 322 17969498406649368415 508706 21 18262520277922268156 550186 7 16951394439130536045 563151 248 16486711190174443479 6086070 43 18339346514325552494 Shape Multipoles 8 1.8.3 OEShape openeye.com 2012.11.26 711.7 12.7 3.57 2.5 7.39 0.57 0.35 0.85 3.82 1.55 -0.28 -5.15 -0.08 3.05 Shape Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 1570.853 Shape Volume 7 1.8.3 OEShape openeye.com 2012.11.26 386.1 Conformer RMSD 7 2009.12.11 1 Diverse Conformer ID List 6 2012.02.08 1 23 24 16 19 14 25 22 26 12 18 20 13 5 9 2 6 10 11 27 28 17 7 15 21 4 29 3 8 Charge MMFF94 Partial 2 1.7.6 OEChem openeye.com 2012.02.08 48 1 -0.34 10 -0.66 11 -0.62 12 0.12 13 -0.06 14 0.03 15 0.44 16 0.62 17 0.03 18 0.4 19 -0.14 2 -0.34 20 0.54 21 0.3 22 -0.15 23 0.3 24 -0.15 25 -0.15 26 -0.15 27 -0.15 28 -0.14 29 -0.14 3 -0.34 30 -0.15 31 -0.15 32 -0.14 33 -0.15 34 -0.15 35 0.16 36 1.16 37 1.16 38 0.14 4 -0.34 44 0.15 45 0.15 46 0.15 5 -0.34 50 0.15 51 0.15 52 0.15 53 0.15 54 0.15 55 0.15 56 0.15 6 -0.34 7 -0.57 8 -0.57 9 -0.47 Count Effective Rotor 7 1.7.6 OEChem ncbi.nlm.nih.gov 2012.01.18 7 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.1 OEShape openeye.com 2012.02.08 7 1 11 acceptor 1 7 acceptor 1 8 acceptor 6 11 14 18 22 31 35 rings 6 17 26 27 32 33 34 rings 6 19 24 25 28 29 30 rings 6 9 12 13 14 18 20 rings 38 0 0 0 0 0 0 0 1 1