9808719 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 17 16 8 8 8 8 8 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 3 4 5 5 6 6 7 8 8 9 9 9 10 10 10 11 11 11 11 12 12 12 13 13 13 14 14 14 15 15 15 16 16 17 17 17 18 18 18 19 20 22 22 23 24 24 25 25 27 27 28 28 29 30 31 31 32 32 32 33 33 34 34 36 36 37 39 39 39 40 40 40 41 41 41 35 19 21 23 40 26 30 41 38 75 38 20 21 21 26 57 25 27 32 12 13 17 42 15 43 44 14 45 46 16 49 50 16 47 48 51 52 18 53 54 19 55 56 20 22 23 24 31 30 58 26 29 28 34 29 33 59 35 35 62 38 60 61 36 63 37 64 37 39 65 66 67 68 69 70 71 72 73 74 1 1 1 1 1 2 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2 2 1 1 1 2 2 1 1 1 1 2 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 13.4028 9.2157 9.9577 7.6279 13.6119 5.4978 4.2086 9.2157 7.6279 5.5443 11.6803 12.5938 11.5757 12.3847 13.4028 13.2983 10.8712 10.9758 10.1667 10.1667 8.6279 10.9758 10.8712 11.8893 6.1279 7.1279 4.5981 4.5981 5.5443 12.6983 11.6803 5.855 3.732 3.732 12.5938 2.866 2.866 5.1871 2 9.8532 14.4209 11.1139 12.2471 13.0398 11.3039 10.9797 13.6746 13.9988 12.7314 11.9388 13.9168 13.4483 10.5994 10.2753 11.2476 11.5717 7.3179 11.9541 5.7369 6.4019 6.2375 11.6154 3.732 3.732 2.3291 1.69 1.4631 2.31 9.2366 9.7884 10.4698 14.0565 14.9225 14.7853 5.0837 -3.4981 0.162 -3.136 1.085 -1.5091 3.6691 2.5124 -1.456 -0.647 1.0238 2.0231 1.6164 3.0176 3.6054 2.2041 3.1987 1.4353 0.4408 -0.147 -1.147 -0.647 -1.7348 -2.7293 -1.328 0.219 0.219 0.719 -0.281 -0.5857 -1.9158 -3.3171 1.9743 -0.781 1.219 -2.9104 -0.281 0.719 2.7186 -0.781 -4.1306 -2.0969 2.2753 1.1024 1.1857 3.5749 2.8467 1.6469 2.375 4.1194 4.0361 3.1554 3.8002 1.9926 1.2644 -0.1165 0.6117 -1.1839 -0.7114 -1.175 1.6823 2.4622 -3.9337 -1.401 1.839 1.029 -0.244 -1.091 -1.3179 -4.0658 -4.7472 -4.1954 -2.5985 -2.4613 -1.5953 4.1306 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 2 2 8 8 10 10 19 22 22 23 24 25 27 27 28 28 30 31 33 34 36 19 21 20 21 25 27 20 23 24 31 30 29 28 34 29 33 35 35 36 37 37 0 Compound Canonicalized 5 2010.07.16 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 894 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 7 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 2 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 10 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371F07B3800440000000000000000000000000162C000003060C000000000005801FC00001E06100800000D0EC1DE2633DFF3CC1608AC0325F27C0082F8A9672F7909D835BE6FD88E66F3E5BFBB9431286EC113D8E9A7F8C9F09E0D000301000A08001A00060200141000000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 2-[2-[[4-(4-chloro-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)thiazol-2-yl]carbamoyl]-5-methyl-indol-1-yl]acetic acid IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 2-[2-[[[4-(4-chloro-2,5-dimethoxyphenyl)-5-(2-cyclohexylethyl)-2-thiazolyl]amino]-oxomethyl]-5-methyl-1-indolyl]acetic acid IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 2-[2-[[4-(4-chloro-2,5-dimethoxyphenyl)-5-(2-cyclohexylethyl)-1,3-thiazol-2-yl]carbamoyl]-5-methylindol-1-yl]acetic acid IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 2-[2-[[4-(4-chloranyl-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)-1,3-thiazol-2-yl]carbamoyl]-5-methyl-indol-1-yl]ethanoic acid IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 2-[2-[[4-(4-chloro-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)thiazol-2-yl]carbamoyl]-5-methyl-indol-1-yl]acetic acid InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C31H34ClN3O5S/c1-18-9-11-23-20(13-18)14-24(35(23)17-28(36)37)30(38)34-31-33-29(21-15-26(40-3)22(32)16-25(21)39-2)27(41-31)12-10-19-7-5-4-6-8-19/h9,11,13-16,19H,4-8,10,12,17H2,1-3H3,(H,36,37)(H,33,34,38) InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 ITSFURYNWBMEFN-UHFFFAOYSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 8.2 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 595.19077 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C31H34ClN3O5S Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 596.13676 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 CC1=CC2=C(C=C1)N(C(=C2)C(=O)NC3=NC(=C(S3)CCC4CCCCC4)C5=CC(=C(C=C5OC)Cl)OC)CC(=O)O SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 CC1=CC2=C(C=C1)N(C(=C2)C(=O)NC3=NC(=C(S3)CCC4CCCCC4)C5=CC(=C(C=C5OC)Cl)OC)CC(=O)O Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 131 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 595.19077 41 0 0 0 0 0 0 0 1 3