9614472
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
8
8
8
8
8
7
7
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
3
-1
9
1
1
1
2
3
4
5
6
6
6
7
7
7
8
9
10
10
11
11
12
12
13
13
14
15
15
15
16
17
17
18
19
19
20
20
21
21
21
22
24
25
25
26
26
27
27
28
29
29
29
30
30
30
32
32
32
33
33
34
34
35
36
22
32
23
9
9
31
8
13
40
19
23
44
20
14
11
24
31
52
35
36
14
17
16
16
18
21
37
18
38
39
22
25
23
24
41
42
43
26
29
27
45
28
46
28
47
48
49
50
51
31
33
34
53
54
55
35
56
36
57
58
59
1
1
2
1
2
2
1
1
1
1
1
1
2
1
1
2
1
1
2
1
2
1
1
2
1
1
1
2
1
1
1
2
1
1
1
1
1
2
1
1
1
1
1
2
1
1
1
1
1
1
2
1
1
1
1
1
1
2
1
1
1
8
-1
6
20
24
23
2
1
10
-1
11
24
29
20
2
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
1.5571
1.1862
4.9489
5.0517
-4.1135
1.7943
1.1349
0.456
4.6298
-2.2806
-3.615
-8.6415
2.3739
3.7577
3.4763
4.3089
1.5414
2.0925
1.9216
-0.0151
4.0651
2.1175
0.8568
-1.5148
2.5041
2.8964
3.2829
3.4792
-2.1025
-5.9174
-4.469
2.3255
-6.8571
-6.3383
-8.1947
-7.6992
5.388
0.4591
1.4334
2.4061
3.4189
5.0354
4.2021
0.7378
2.3972
3.0532
3.7373
4.0856
-2.4839
-1.3402
-2.9004
-3.9338
3.2426
2.5722
1.7282
-6.5698
-5.6598
-8.9671
-8.0799
-3.3313
-1.4568
0.7184
1.2583
1.4489
1.1808
-2.0234
1.0511
1.4557
0.0005
-0.1245
0.1304
2.4133
2.5551
4.8844
3.7908
3.5072
4.7428
-3.1942
-0.1139
6.2057
-3.8264
-1.2978
-0.2125
-3.7169
-4.9811
-4.8717
-5.5037
-0.6076
0.4655
0.6438
-2.3865
0.7055
0.0581
0.5252
-0.0933
3.9041
3.4386
5.5871
0.3937
7.0298
6.3516
6.2706
-1.6976
-3.2821
-5.4796
-5.2798
-6.4029
-1.6313
-0.5685
0.0795
-0.7788
-2.8515
-1.5151
-2.0536
1.0207
-0.1169
0.6982
-0.4021
2.3692
-2.3891
0.6295
-1.4958
1.4931
-0.5381
-0.0888
-0.6036
-0.3323
0.0565
-0.1304
-0.175
-0.1978
-0.0951
0.4813
0.2443
0.039
0.3787
0.0015
-0.9234
0.8445
1.2293
-1.2261
-0.9673
-1.1531
1.3026
-1.0798
0.148
-2.2893
0.3549
0.6366
3.1106
1.3513
-0.9062
1.0384
-1.1182
0.3268
-0.031
0.5626
-0.7131
0.5232
0.3577
1.9284
0.7898
-2.1373
2.2554
-1.9781
0.2051
-2.2375
-3.0731
-2.5859
-0.8346
3.486
2.4957
3.9639
2.3487
-1.7331
1.7807
-2.0863
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0092B48800000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
132.9549
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
76.217
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10675989 125 18271810176472918300
11297750 10 18043245735152250253
11505856 67 16818289012870713405
12166972 35 18199468754106021107
12788726 201 17326635599854165618
13533116 47 18334582296419764115
14150023 79 18409732901974907535
14565420 104 18339359785668644857
15198563 99 9264747205074718234
15878777 1 12217690319478880494
16096371 109 18409455807944311153
16114785 44 17692811901328596538
19319366 153 18200311142847081861
21049683 118 18053363672805128336
21344244 78 18198049292466792866
21703447 108 18261388902438284809
22311459 1 18411421717354594492
23845131 108 18191868035743065619
249999 5 18409730668692263611
27425 322 18127411365783262644
3627633 1 17618787959714645254
6371380 46 18267313200180652996
6697151 62 18047728435748196575
86090 222 17386016026734792307
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
676.65
17.06
8.79
1.89
53.38
0.33
-0.55
7.41
-2.22
-23.97
-2.75
-0.23
-1.82
-0.86
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1446.292
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
371.2
Conformer
RMSD
7
2009.12.11
1.2
Diverse Conformer
ID List
6
2012.02.08
1
7
13
30
44
18
9
54
22
61
12
48
43
31
29
47
27
71
3
63
68
21
11
28
33
15
14
10
20
32
56
8
38
46
65
62
6
41
34
26
40
42
35
39
2
49
55
45
53
70
50
4
57
52
66
23
64
37
51
25
5
36
17
24
19
16
60
69
67
58
59
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
50
1 -0.36
10 -0.51
11 -0.37
12 -0.62
13 0.1
14 0.13
15 -0.14
16 -0.15
17 -0.15
18 -0.15
19 0.12
2 -0.57
20 0.45
21 0.14
22 0.08
23 0.63
24 0.39
25 -0.15
26 -0.15
27 -0.15
28 -0.15
29 0.06
3 -0.52
30 0.09
31 0.54
32 0.28
33 -0.15
34 -0.15
35 0.16
36 0.16
37 0.15
38 0.15
39 0.15
4 -0.52
40 0.4
44 0.37
45 0.15
46 0.15
47 0.15
48 0.15
5 -0.57
52 0.37
56 0.15
57 0.15
58 0.15
59 0.15
6 -0.46
7 -0.55
8 -0.49
9 0.91
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
11
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
15
1 1 acceptor
1 10 acceptor
1 11 donor
1 12 acceptor
1 2 acceptor
1 3 acceptor
1 3 anion
1 4 acceptor
1 5 acceptor
1 6 donor
1 7 donor
1 8 acceptor
6 12 30 33 34 35 36 rings
6 13 14 15 16 17 18 rings
6 19 22 25 26 27 28 rings
36
0
0
0
2
2
0
0
1
6