Bookmark and Share

Compound Summary for: CID 9565

glymidine

Also known as: Glidiazine, Glycodiazine, Glymidinum, Glycodiazin [German], Glycodiazin, AC1L1TBP, EINECS 206-426-5, UNII-4C5I4BQZ8F
Molecular Formula: C13H15N3O4S   Molecular Weight: 309.3409   InChIKey: QFWPJPIVLCBXFJ-UHFFFAOYSA-N
Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral tissues to insulin. Glycodiazine likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Membrane depolarization stimulates calcium ion influx through voltage-sensitive calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin. It is used for the concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus.   From: DrugBank
Show subcontent titlesTable of Contents
Identification
Related Records
show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)
Biomedical Effects and Toxicity
Literature
Patents
Biomolecular Interactions and Pathways
Biological Test Results
Classification
Chemical and Physical Properties
_ _