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Compound Summary for: CID 853

Thyroxine

Also known as: DL-Thyroxine; Thyroxine, dl-; CHEBI:30660; 2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
Molecular Formula: C15H11I4NO4   Molecular Weight: 776.87002   InChIKey: XUIIKFGFIJCVMT-UHFFFAOYSA-N
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.   From: MeSH
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